Blue warning of severe convective weather

　　The Central Meteorological Observatory continued to issue a blue warning of severe convective weather at 06: 00 on April 5:

　　It is estimated that there will be short-term heavy precipitation in some areas of southern Anhui, northwestern Jiangxi, southeastern Hubei, northeastern and southwestern Hunan, southern Guizhou and northwestern Guangxi from 08: 00 on April 5 to 08: 00 on April 6. It is estimated that the hourly rainfall intensity can reach 30-50 mm, and the local area will reach more than 50 mm. There are hail or thunderstorms and strong winds in parts of southern Anhui, southeastern Hubei, northwestern Jiangxi, southern Hunan, south-central Guizhou and northwestern Guangxi.

　　　　Defense guide:

　　　　1. The government and relevant departments shall, in accordance with their duties, prepare for short-term rainstorm prevention, lightning protection and gale prevention, and the meteorological department shall prepare for artificial hail suppression;

　　　　2. Outdoor pedestrians and staff should reduce outdoor activities and pay attention to stay away from structures such as scaffolding billboards;

　　　　3. Drive poultry and livestock into places with roofs, and close doors and windows to reinforce sheds;

　　　　4. The water operations in relevant waters and passing ships shall take active measures such as returning to Hong Kong to avoid or detour navigation, pay attention to covering building materials at the construction site, and properly arrange outdoor items susceptible to heavy rain, wind and hail;

　　　　5. Check the drainage system of cities, farmland and fish ponds, and prepare for drainage and defense against disasters such as mountain torrents, landslides and mudslides.　　

　　Typhoon blue warning

　　The Central Meteorological Observatory issued a typhoon blue warning at 06: 00 on April 5:

　　This year’s No.4 typhoon "Mesak" (English name: Maysak；; Name source: Cambodia; Meaning of the name: a tree) was formed in the Pacific Northwest on March 28th, strengthened to super typhoon level on March 31st, and then weakened continuously. Today (5th) at 5 o’clock in the morning, its center is located on the northwest Pacific Ocean about 270 kilometers north-east of Manila, Philippines, which is 16.0 degrees north latitude and 123.0 degrees east longitude. The maximum wind force near the center is 9 (tropical storm level, 23 m/s), the lowest pressure in the center is 988 hectopascals, and the radius of the 7-level wind circle is 50-200 kilometers.

　　It is estimated that "Mesak" will move to the northwest at a speed of 20-25 kilometers per hour, and its intensity will gradually weaken. It will land in the coastal area of northeastern Luzon Island in the Philippines (8-9, 20-23 m/s), then pass through the northern part of Luzon Island, and will move into the northeastern South China Sea (7-8, 16-20 m/s) around the evening of the 5th.

　　From 08: 00 on the 5th to 08: 00 on the 6th, there will be strong winds of magnitude 7-8 in bashi channel and the northeastern part of the South China Sea, with gusts of magnitude 9 in some sea areas.

　　Defense guide:

　　1. The government and relevant departments shall, in accordance with their duties, do a good job in typhoon prevention and emergency rescue;

　　2. Take active measures for water operations and passing ships in relevant waters, strengthen port facilities, and prevent ships from anchoring, grounding and collision.

　　(Editor: Su Jessie)

On August 23, Hunan police announced a major case of cross-border telecom fraud using cryptocurrency. The case involved renting communication tools to overseas fraud gangs, involving more than 4 million yuan. The Ouyi wallet address of Xia Mou, the leader of the criminal gang, shows that the encrypted currency used to settle the fraudulent commission is as high as 9 million yuan, nearly 10 million yuan. The gang members mainly trade through the virtual currency USDT to avoid traditional financial supervision.

Wen Jie, deputy head of the new crime investigation brigade of telecommunication network of Linwu County Public Security Bureau, revealed that criminal gangs provide services to overseas fraudsters through "mobile phone port" and "PC terminal". "Mobile phone port" refers to renting a mobile phone number to make fraudulent calls, while "PC side" refers to renting a micro signal for fraud. It is worth noting that the gang members are generally younger, many of them are minors under the age of 18, and they are tempted by high salaries to participate in criminal activities.

The police found detailed records in the suspect’s computer, including the contact information of the merchant, the QQ of the crime, the time and the transaction method. The case involved 86 cities in 18 provinces, and 62 suspects were arrested. The police reminded that criminals use cryptocurrency to evade supervision, and the public should be vigilant and beware of new financial fraud.

Qin Yongcheng’s "First Oil Well" in Daqing Oilfield. Pictures are data pictures.

Qin Yongcheng (right) is with oil workers in Panjin Oilfield. Pictures are data pictures.

　　[Great motherland, unforgettable songs].

　　"Splendid rivers and mountains are picturesque, and the motherland is building a cross-horse. It’s a great honor for me to be an oil worker and travel around the world wearing an aluminum helmet … …” This heroic ode to oil workers is not only a clarion call to encourage oil workers from generation to generation to join in the construction of the motherland, but also an overall portrayal of the outstanding heroes of the working class in China. Although it was written more than half a century ago, it is still so exciting and exciting to sing today.

　　The composer Qin Yongcheng (1933— 2015) is the first generation composer trained in New China. During more than half a century’s creative career, he has created a large number of musical works with high artistic achievements and wide social influence, such as the song "I offer oil for the motherland", "Chairman Mao travels all over the motherland", My People，My Country, vocal concerto "Haiyan", symphonic poem "Two Little Cowboys" and movie music "Entrepreneurship" and "Marshal and Soldiers". He made great contributions to the music, art and education in our country all his life.

　　Three days with the "Iron Man"

　　In 1964, a notice brought Qin Yongcheng into close contact with Li Jiefu, a famous composer and president of Shenyang Conservatory of Music. It was this notice that made him have an indissoluble bond with oil workers all his life. In March this year, China Musicians Association organized some composers to experience life in Daqing Oilfield and created a batch of works reflecting oil workers. Dean Hijacking also received a notice, asking him to report to Sarthou, Heilongjiang Province on March 20th. After receiving the notice, the dean of the robbery immediately made preparations for leaving. Due to physical reasons, the college is going to find a young man to accompany the dean of the robbery to "go north". At the suggestion of the dean of the robbery, Qin Yongcheng will accompany him. Unfortunately, Qin Yongcheng was suffering from a high fever and had been in bed for three days. Upon hearing this, Dean Hijacking personally visited Qin Yongcheng’s home and told him to rest at ease for illness. In the face of this rare opportunity, Qin Yongcheng looked forward to his early recovery. Although his fever had gone down the next day, he was still very weak, and insisted on accompanying Dean Jiefu.

　　On the evening of 19th, Qin Yongcheng got his wish and boarded the train to the north. In the car, Qin Yongcheng finally put forward the question that was hidden in his heart: "Where are we going to Sarthou?" Dean Hijacking told him quietly: "Sarthou is a big oil field, called Daqing Oilfield, and it is still confidential." After moving to Daqing, Qin Yongcheng lived with many famous musicians such as Lv Ji, Qu Wei, Wang Xin, Zhang Lu and Jiefu in the guest house of Daqing Petroleum Command.

　　Since the next day, the oil field has arranged courses for musicians to introduce oil-related knowledge, from exploration and drilling to oil production and refining for ten days, with one content per day. Ten days later, the oilfield arranged for them to experience life in the first line. Qin Yongcheng, Jiefu and Wang Xin (songwriters of "Singing the Motherland") were assigned to the "1205 Hero Drilling Team" with Wang Jinxi, the "Iron Man", and lived together with the "Iron Man" for three days. During this period, Wang Jinxi told Qin Yongcheng that when he held a People’s Congress in Beijing in 1959, he saw that the buses in Beijing were in a heavy mood because of lack of oil and carrying gas bags. He also listened to him tell the story of the Daqing Petroleum Congress. In the spring of 1960, Wang Jinxi’s drilling team was in Yumen Oilfield. When it was heard that a large oil field had been discovered in the north, the whole country was going to hold a general meeting there, and immediately asked the superior to fight. They said goodbye to their relatives and boarded the train going north in their light clothes. Faced with the harsh climate, hard living and working environment, and poor equipment, oil workers shouted the loud slogan of "if you have the conditions, you should go if you don’t have the conditions" in order to get rid of the label of "poor oil" as soon as possible and break the economic blockade of western hostile forces. "When the oil workers roar, the earth will shake three times."Qin Yongcheng’s soul was strongly shocked and greatly impacted by his earth-shattering fearless revolutionary heroism. Especially in the days spent with Wang Jinxi and his heroic drilling crew, Qin Yongcheng’s understanding of oil workers has been greatly sublimated, and he has a strong emotional resonance. He is determined to create works that can reflect the spirit of oil workers to express his high respect for them.

　　A masterpiece completed in the canteen of the hostel.

　　After three days of experience, Qin Yongcheng returned to the guest house, and the Propaganda Department of the Party Committee of the Oilfield prepared a batch of lyrics reflecting the work and life of Daqing Oilfield and oil workers for them, hoping that composers would compose music for them. After the old composers had chosen the lyrics, Qin Yongcheng also chose them. At this time, a lyric jumped into his eyes, which was written by oil worker Xue Zhuguo, "I offer oil for my motherland." This first-person lyric is vivid and vivid, which vividly depicts the heroic and optimistic mood of oil workers and the fearless revolutionary spirit of fighting against the world. The more Qin Yongcheng watched it, the more he liked it. The more he watched it, the more excited he became. At this moment, he was inspired and full of thoughts. In the canteen of the hostel, he finished writing this work in just 20 minutes.

　　Inspired by the artistic conception of the lyrics, the prelude of the song adopts a fast speed, a lively and elastic rhythm, and a fluctuating melody line, like a train full of oil workers galloping in the splendid rivers and mountains of the motherland, from the northwest of the motherland to the northeast thousands of miles away. Then, the heroic song of the oil workers was introduced: "The beautiful rivers and mountains are picturesque, and the motherland is building a beautiful horse. I am honored to be an oil worker and wear an aluminum helmet to travel all over the world." The melody of the song is broad, fresh and smooth, which vividly depicts the bold spirit of oil workers and the revolutionary optimism full of pride and self-confidence. On the word "kua" of "kua steed", the melody absorbs the elements of rap music and adopts a sliding tone, which is not only in line with the rhyme of Chinese four tones but also forceful, and can better highlight the bold and hearty character of oil workers. These four sentences are lyrical paragraphs, which vividly depict the heroic fighting spirit and optimistic spirit of oil workers moving to the north and south and being at home all over the world.

　　In order to show the dauntless heroism spirit and heroic spirit of oil workers, who are "fearless of heaven, fearless of earth, and fearless of storm, thunder and lightning", Qin Yongcheng treated these two lyrics into short and powerful eight-point dotted notes and syncopated rhythm, which made the music more powerful and dynamic. At the same time, it not only forms a sharp contrast with the previous lyric paragraphs, but also lays a good foundation for the climax of the whole song that appears later.

　　The climax of the song is in the last two phrases, "I contribute oil to my motherland, where there is oil, my home is there". In order to make the climax of the song more prominent and infectious, Qin Yongcheng ingeniously treated the first beat at the beginning of this sentence as a rest, and started the word "I am" from the weak beat to highlight the word "ancestor" in the next section. Then, on the word "oil" for "offering oil", the melody adopts a circuitous upward movement, forming a large-span 10-degree interval in the range. In the last four bars of the song, Qin Yongcheng skillfully used the drawl of China’s traditional opera music for reference. It is worth mentioning that in the first draft of the work, the last four sections are not like this, but after Qin Yongcheng returned to school, he sang the work to friends and students, listened to and adopted everyone’s suggestions, and changed the original last simple melody into the current one-stop drawl. In this way, the music is more infectious and dynamic, which not only depicts the free and easy character of oil workers, but also makes the whole song end in an atmosphere full of optimism and pride. The revised work was published in the journal "Music Life" of Liaoning Branch of China Music Association, which soon became a hero’s ode to oil workers in the north and south of the motherland and inside and outside the Great Wall.

　　The only "composer of oil workers"

　　The first singer of this song, Liu Bingyi, a famous baritone singer of the former Central Orchestra, also played an important role in the promotion of this song. He and Qin Yongcheng also became attached to this song, and it was sung for 50 years. And Qin Yongcheng also started from this song, and successively created a number of excellent works reflecting oil workers. In 1973, as a key project of the Ministry of Culture, Changying filmed a feature film "Entrepreneurship" reflecting the Daqing Petroleum Congress, and specially invited Qin Yongcheng to create music for this film. Qin Yongcheng lived up to expectations, and created a number of well-known songs in his film music, such as Looking at Beijing with deep feelings, Entrepreneurial songs, and The Fragrance of Oil in Tianya Wan Li. Because of Qin Yongcheng’s outstanding contribution to the creation of oil-related music, the vast number of oil workers are familiar with the name Qin Yongcheng and affectionately call him "the composer of oil workers". In 1994, China Petroleum and Natural Gas Corporation (formerly the Ministry of Petroleum Industry) awarded Qin Yongcheng the honorary title of "composer of oil workers", and he was the only composer in China to win this honor. In 1996, China Records Corporation awarded Qin Yongcheng the "Golden Record Award" for this work, which was later included in the 20th century Chinese classics.

　　Praising the motherland and people and eulogizing the times and life are the themes of Qin Yongcheng’s life creation. It is precisely because of Qin Yongcheng’s deep patriotism, deep thoughts and feelings for the broad masses of the people, including oil workers, rich musical language based on Chinese excellent musical culture, and continuous absorption of rich nutrition and creative sources in the long-term in-depth social life that he created such immortal masterpieces represented by "I Contribute Oil to the Motherland", which are full of positive energy and the main theme of the times, and have high artistic value and appeal to both refined and popular tastes. (Author: Wei Huang, former vice president and second-level professor of Shenyang Conservatory of Music)

1905 movie network news The movie key, which is directed by the screenwriter and starring,, and will be extended to February 28. As of 22:00 on January 18th, the cumulative box office of the film was 844 million yuan, winning the single-day box office champion for 18 consecutive days.

The annual meeting can’t stop! It tells the story that fitter Hu Jianlin was transferred to the group headquarters by mistake and became a gold collar. At the annual meeting of the group, he exposed the corrupt executives of the factory and finally saved the factory. The film’s joyful irony of the strange phenomenon in the workplace has deeply resonated with countless migrant workers, helping them to climb their reputation. Douban scored as high as 8.2, making it the highest domestic comedy in Douban in the past five years.

Cctv news Once, he dedicated himself to the country, and his iron will showed the true colors of soldiers; Today, he is physically disabled and determined, and he has retired as a "poverty fighter." He is Chen Zhikun. He was drafted into the army in 1981. Unfortunately, he was injured in the battle and won the second class merit. He could have enjoyed the preferential treatment of the state for a lifetime, but he was glowing on the road to entrepreneurship. He believes that "the body can’t move, the brain can move, and it can make a little contribution to society."

After Chen Zhikun retired from the army, Zhenning County, Anshun City, Guizhou Province, provided him with a house of more than 90 square meters in accordance with the regulations of the state on special care for civil affairs, and he can also be supported by the state for life. However, he resolutely rejected the kindness of the organization to arrange work for him and decided to start his own business.

Chen Zhikun had motorcycle maintenance technology when he was in the army. After returning home, he re-learned this craft with reference to a large number of materials, and he quickly became a master in the industry while learning and practicing. In 1994, Chen Zhikun opened a motorcycle repair department. Apart from excellent repair technology and low cost, he also recruited unemployed and disabled young people in society to learn repair technology for free. It didn’t take long for many apprentices in Chen Zhikun to become one of the few million households at that time with the good skills they learned.

With years of hard work, Chen Zhikun has created a miracle of entrepreneurship for the disabled. At that time, Chen Zhikun’s hometown was still poor, and he was deeply disturbed. He decided to drive his neighbors to get rich together. So, Chen Zhikun said goodbye to his family with a start-up capital of 500,000 yuan and returned to Qishan Village, Shaoxing City, Zhejiang Province, where he was born and raised.

After discussing with the village cadres, he founded the 2,000-square-meter "Rongjun Breeding Demonstration Farm in Qishan Village, Machang Township, Zhenning Autonomous County" to attract many poor households in the village to work in the farm. In 2007, Chen Zhikun founded Guizhou Qianningxiang Green Food Development Co., Ltd., focusing on breeding sows and fattening pigs, and in 2008, he founded Rongjun Breeding Cooperative. Under the leadership of Chen Zhikun, a through-train system of breeding, storage, transportation and sales has been formed, and more than 40 technical backbones have been trained. In training, purchasing breeding pigs, breeding, epidemic prevention, technical guidance, purchase and sales, he gave 40% of his annual profits to veterans and disabled people engaged in farming.

Feng Zufang is one of the villagers that Chen Zhikun helped. Feng Zufang was engaged in raising pigs before he joined Chen Zhikun’s company, but because he didn’t know scientific breeding technology, he could only make ends meet and sometimes even lost money. After joining the breeding association, her family’s economic income has increased significantly. At most, she can slaughter about 100 pigs a year, with an annual income of not less than 20,000 yuan.

Chen Zhikun "taught people to fish" through his own technical ability, so that those poor people can completely end the poverty situation. He has trained more than 8,000 breeding technicians for free, and inspired more than 9,000 farmers to practice scientific pig raising.

He is a fearless soldier on the battlefield; In starting a business, he is an entrepreneur who cares about his fellow villagers and elders, veterans and disabled people. He showed us the inner qualities of a soldier with his actions. Let’s say thank you to him!

　　In terms of appearance, the M50 continues the overall shape and general design of i4, and it has a strong recognition due to the penetrating double kidney grille, three-stage air intake opening and smooth back lines. Compared with the BMW i4, the details of the front enclosure, the rear enclosure and the rim of the M50 model have been upgraded in a sporty way, and more carbon fiber materials have been added to reduce the weight of the car. At the same time, the front grille of the new car is also equipped with the M logo to show its identity. In terms of size, the length, width and height of the new car are 4785/1852/1448mm and the wheelbase is 2856 mm. Sales Tel: 13821856177 Manager Zhang

　　The BMW i4 M50 has heat dissipation openings at the front enclosure and the front fender, and the inside of the rim is equipped with large brake calipers and brake discs. Coming to the rear, the M50 model provides a carbon fiber spoiler and diffuser, which, although not exhausted, is domineering enough.

　　In the rear part, the BMW i4 M50 presents a typical "pear shape", and the diffuser shape surrounded by it makes the whole car look more solid. Generally speaking, the slender column, short front overhang, the door with frameless windows flow smoothly into the rear roof line, which is a perfect coupe-shaped outline.

　　The M50 supports optional M-carbon fiber exterior components, including front air intake, exterior rearview mirror cover, rear side decoration and a new rear spoiler with the same geometric design, which further greatly improves the sports texture of the whole vehicle, not only ensuring elegance, but also revealing a "fierce" momentum.

　　Entering the interior, the interior part of M50 is similar to the layout of the same fuel car, revealing a low-key gorgeous. The M50 is designed with a double screen inside. The left half is a 12.3-inch LCD instrument with an obvious M logo on the upper left and a 14.9-inch central control touch screen on the right half. The double screen is not only larger in overall area, but also slightly tilted towards the driver according to the ergonomic principle. This driver-oriented design concept is also deeply recognized by the author. The bottom of the screen extends to the central control position, and the physical gear handle and a large number of physical touch buttons are reserved, so that the interaction in actual driving is more in line with the driving habit of oil trucks, and the interaction risk of the whole vehicle after a single screen failure is also reduced.

　　In terms of seats, the M50 seat is wrapped in all-black material, and the added blue stitching design makes the interior space full of movement. At the same time, the M sports seat uses a barrel-shaped deep concave shape, which can provide good side support for drivers and passengers. The seat also provides functions such as electric adjustment, seat heating and ventilation, which allows drivers to have a more focused driving experience while driving. Generally speaking, The interior is assembled with the interior of BMW M family, such as M-sports multifunctional leather steering wheel and M-sports seat, all of which increase the exclusive and unique sense of sports luxury of M50. In the whole vehicle space, the author’s height is 187 and his weight is 170 kg, and he is used to sitting in the back. Therefore, in the rear performance of M50, the original standard axle size plus the sliding roof will make the rear space feel depressed and the comfort performance is average.

　　The M50 is equipped with BMW’s fifth-generation eDrive electric drive system. The front and rear double motors of the vehicle are designed, which can provide the maximum output power of 400 kW, the peak torque is as high as 795 Nm, and the acceleration of 100 kilometers takes only 3.9 seconds. Under the CLTC standard, the maximum cruising range of the vehicle can reach 560 kilometers. As for the chassis, the M50 adopts the structure of front double-ball-joint spring shock-absorbing strut and rear five-bar linkage, and the original 4-series foundation is added with a large-capacity battery. The whole feeling is like lying on the ground, with a strong sense of heaviness. Moreover, the suspension supports soft and hard adjustment, so there will be different damping in different modes, and the dynamic feedback of the car body will change accordingly. Advanced chassis technology, intelligent lightweight design and excellent aerodynamic characteristics have shaped extremely exaggerated sports performance.

　　Tianjin zhongxing north international trading co., ltd

　　Address: Room 206, Hall B, International Automobile City, Tianjin Port Bonded Area

　　Sales Tel: 13821856177 Manager Zhang

　　Disclaimer: The above car purchase preferential information is provided by the comprehensive dealers of this website, and the price fluctuates greatly due to market factors, which is only for car purchase reference; The distributor is responsible for its authenticity, accuracy and legality, and this website does not provide any guarantee or assume any legal responsibility.

　　[Aika car test drive original]

　　After a whole year of silence, Kaiyi, a brand of Chery Automobile, once again launched a brand-new model — — Kaiyi Xuanjie, the new car is positioned as a compact SUV, and the official pre-sale price range is 589-89900 yuan. In the future, it will compete with Geely Emgrand GS and Beiqi Zhixing. In addition to the young and fashionable appearance, what are the highlights in the configuration of Xuanjie? How does it feel to drive?

　　We came to picturesque Yunnan for this test drive, and experienced the top model of Kaiyi Xuanjie, 1.5L CVT Yao, which is the first mass-produced new car from Yibin Intelligent Factory built by Yibin Automobile Industry Development Investment Co., Ltd. (holding 50.5% of the shares) and Pushi Group (holding 0.5% of the shares) controlled by Yibin Wuliangye Group. Can Hyun Jie really impress young consumers today?

On February 28th, according to Sina Technology, the customer service of Tesla China responded to the rumor that FSD is fully autonomous driving and will soon enter China. At present, there is no exact time for the launch of FSD in China, so we can keep an eye on it.

According to the feedback submitted by the IT House friends, a blogger "Tesla China Analyst" posted on Twitter this afternoon that FSD will enter China within two weeks and released a photo of the car-machine interface.

This is not the first time this year that Tesla FSD has entered China. In January of this year, the news that Tesla FSD version 12 will be pushed in China at 3 am on January 8, 2024 Beijing time appeared on the Internet. Some insiders of Tesla China responded: "" This rumor also said that "this version will be fully launched in China for the first time", and it also brought "fine adjustment of the driver’s seat door angle" and other contents.

However, as early as last November, with, Tesla FSD was also considered to enter the "countdown" stage. According to the report of China Fund at that time, Tesla China once responded: "".

On the 10th of this month, the news source @Teslascope monitored that Tesla has started to push the update of 2023.44.30.15 to its employees and special groups, including the FSD Beta 12.2 version of the assisted driving function. Tesla’s last FSD Beta version was V12.1.2, which was only open to employees and about 100 public beta users. These 100 people are probably the "special groups" mentioned by Tesla.

Related reading:

FSD Beta 12.2 has been opened to Tesla employees and special groups.

"Tesla China insiders responded to" Pushing FSD 12 Autopilot in China on January 8 ":False News"

Through ten groups of questions and answers, this paper gives you the function and application of popular science stem cells, and shows you the important position of stem cell therapy in modern medical care.

Mother, the pilot of the boat of life, not only gave birth to us, but also promoted the reproduction of mankind. She is a great inheritor of life and a transmitter of love.

Cells, the weavers of the web of life, constitute the cornerstone of the human body, which is a miracle exhibitor with various forms and complicated functions.

The human body is a magnificent movement interwoven with countless cells, the harmonious resonance of 240 kinds and 60 trillion cells, and the subtle fusion of 4 major organizations, 36 organs and 8 major systems.

She is a special cell, but also the guardian of the source of life. She can regenerate new cells, replace aging cells and repair damaged tissues and organs. She is the mother of the cell world.

This kind of cell is the root of our life-stem cells.

With the progress of science, stem cell research has become one of the most advanced and active research directions in the global medical field.

However, for the general public, what exactly are stem cells? What does it do? What kind of people are suitable for repair intervention through stem cells? What are the risks even in treatment? This article will help you understand these questions easily through ten groups of questions and answers.

Ten questions and answers about stem cells

01

What are stem cells?

Stem cells are cells with self-renewal function and multi-directional differentiation ability.

Under certain conditions, these cells can differentiate into more than 220 different functional cells in human body. Because of its remarkable homing effect, stem cells can repair and replace damaged cells and promote organ regeneration. They are the basic cells that constitute various tissues and organs of the human body, so they are known as "the source of life" and are often called "universal cells" in the medical field.

02

What are the classifications of stem cells?

Scientific research shows that stem cells exist not only in embryos, but also in adults, which can be extracted from cord blood, umbilical cord, placenta, bone marrow, fat and other tissues.

Stem cells are divided into totipotent stem cells, pluripotent stem cells and unipotent stem cells according to their extensive differentiation ability.

Stem cells can be divided into embryonic stem cells and adult stem cells according to their stages of embryonic development.

According to the tissue type of stem cell differentiation, it can be divided into hematopoietic stem cells and mesenchymal stem cells.

03

What is stem cell therapy?

"Stem cell therapy" refers to a medical intervention that extracts stem cells from patients or uses other stem cells, cultivates them under laboratory conditions, and then transfuses them into patients through specific transplantation techniques, so as to repair the cells and tissues that have lost their functions, thus promoting their regeneration and improving their symptoms. At present, hematopoietic stem cells and mesenchymal stem cells are widely used in clinic.

04

What is the difference between autologous and allogeneic stem cells?

Autologous stem cells are derived from patients themselves, which have perfect tissue compatibility, no need for matching, high utilization rate of transplanted cells and no rejection.

Allogeneic stem cells are derived from individuals other than patients and have low immunogenicity. Autologous stem cells are not recommended for people with infectious diseases, major genetic diseases or other health problems.

05

How can stem cells be used to treat diseases?

Cells are the basic unit of life. Human life is accompanied by the process of self-replication and differentiation of stem cells from birth to growth. The ability of stem cells to treat diseases mainly stems from their biological characteristics, which include:

The ability of long-term survival and continuous self-replication;

It can differentiate across different lines and germ layers, showing high plasticity;

And its chemical tendency, that is, homing effect, provides an important biological basis for cell therapy.

06

Is stem cell therapy risky?

Compared with conventional drug therapy, stem cell therapy is considered safer and has fewer side effects. But this does not mean that the risk is zero. Looking at stem cell therapy objectively, the following are some main risks of stem cell therapy:

Tumor development: If stem cells divide or differentiate into abnormal cells uncontrollably, it may lead to cancer. This mainly applies to embryonic or fetal stem cells, or reprogrammed stem cells, because the risk is based on their pluripotency.

Immune rejection: The body may regard foreign stem cells as a threat and attack them, leading to inflammation and injury. This is more likely to happen in hematopoietic stem cells (HSC).

Infection or complications related to invasive medical procedures: Stem cell therapy may lead to infection or complications related to invasive medical procedures.

Drug interaction: Stem cell therapy may have unpredictable interactions with other drugs taken by patients, which may lead to adverse drug interactions.

Unconfirmed or untested stem cell therapy: There is also the risk that unscrupulous practitioners provide unconfirmed or untested stem cell therapy, which may be unsafe or effective.

The effect of treatment is uncertain: patients should also realize that stem cell therapy does not guarantee a cure, and in some cases, it may not be effective at all. Stem cell therapy may not provide lasting results, and patients may need additional treatment.

It should be noted that these risks may be different due to individual differences, treatment methods, stem cell types and other factors. Before receiving stem cell therapy, patients should fully discuss these risks with doctors and weigh the potential benefits and risks of treatment.

07

What diseases can stem cell therapy treat?

Stem cell therapy is mainly used in the fields of treatment, health care and beauty, and it is also used to improve some refractory diseases.

Heart disease: Stem cells can regenerate damaged heart cells and maintain the health and vitality of the heart through a specific process of induced differentiation in the treatment of heart disease.

Prevention and treatment of Alzheimer’s disease: Injecting induced differentiated stem cells can replace aging brain cells and improve cognitive function.

Treatment of liver cirrhosis: generate liver cells through differentiation, and promote the regeneration and repair of liver cells.

Cancer treatment: Directionally differentiated stem cells can enhance the body’s immune function and help fight tumors.

Treatment of premature ovarian failure: Stem cell therapy can restore ovarian function, promote the repair of damaged tissues, improve ovarian microenvironment, enhance reproductive capacity, prevent follicular atresia and promote follicular renewal.

Male hypofunction: Stem cell therapy can repair the aging of reproductive system, improve sexual function, maintain the balance of sex hormones, reduce nocturia, relieve the symptoms of prostatic hyperplasia, and help prevent prostate hypertrophy and other problems.

Enhance muscle function: with the increase of age, muscle function weakens, strength and relaxation function decline, and the body is bloated. Stem cell therapy can improve muscle function, enhance strength, improve body shape and show youthfulness.

08

What is the effect of stem cell therapy?

Stem cell therapy can be carried out by systemic infusion or fixed-point intervention. Clinicians adopt appropriate cell types and treatment strategies according to patients’ health status and disease needs.

Because this treatment can directly intervene in the cause of disease, avoid other physical injuries that may be caused by drugs and surgery, and help regulate the sub-health state, the effect is usually not limited to treating diseases, but also improving the overall function.

09

Is there an age limit for stem cell transfusion?

Traditionally, some types of stem cell transplantation, such as allogeneic bone marrow transplantation, often have age restrictions, and it is usually recommended to be 50 years old or under 45 years old. However, with the progress of medical technology, this limitation is being broken.

For example, it has been reported that a 71-year-old patient successfully received autologous hematopoietic stem cell transplantation, and a 69-year-old woman also successfully received her son’s hematopoietic stem cell transplantation.

These cases show that under proper medical conditions and monitoring, elderly patients may also successfully receive stem cell transfusion therapy, which proves that the age limit is gradually relaxing.

10

What are the taboo populations of stem cells?

Patients with advanced malignant brain tumors, especially brain tumors;

Patients with shock or general failure with abnormal vital signs (requiring disease correction) and those who do not cooperate with the examination;

Patients with heart, lung, liver, kidney and other important organ dysfunction (multiple organ dysfunction syndrome);

Patients with dysfunction of coagulation mechanism;

Patients with severe local infection;

Patients with positive serological results (such as HIV, hepatitis B, syphilis, etc.);

People with high allergic constitution or severe allergic history;

People with nervous system diseases or diseases that have not been diagnosed;

This group is in a special situation and has uncontrollable risks, so it needs careful diagnosis and treatment.

Write it at the end

Stem cells have excellent regeneration and repair functions, and these abilities will gradually weaken with age. Therefore, it is an increasingly popular choice to store healthy stem cells as early as possible, which will provide the possibility for future health management and disease treatment.

The 21st century will be the era of cell therapy, and the application of stem cells and immune cells is expected to play an important role in clinical treatment.

However, at present, except for the mature clinical application of hematopoietic stem cell transplantation, other types of stem cell therapy are mostly in the research stage, and strictly designed clinical trials are needed to prove their clinical advantages, safety and effectiveness, which need further study.

Moreover, non-compliant and eager stem cell therapy and research not only threaten the safety of patients, but also hinder the improvement of stem cell therapy and its research level, which needs the attention of legal supervision, and patients with hope in stem cell therapy should also be alert to fraud and pay attention to its development and related policies and regulations.

Original title: "Why do you call her" the mother of cells ":Ten questions and ten answers about stem cells, and learn about her magic with you"

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　　In the first three quarters, all localities and departments thoroughly implemented the decision-making arrangements of the CPC Central Committee and the State Council, effectively coordinated the two overall domestic and international situations, actively promoted the high-quality development of industry, and maintained a steady growth of the industrial economy as a whole. The national industrial production above designated size continued its rapid growth trend since the fourth quarter of last year, the export of industrial products accelerated quarter by quarter, the profits of enterprises maintained growth, the development of high-end, intelligent and green manufacturing industry steadily advanced, and industrial enterprises expected to improve their future operating conditions and their confidence increased.

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　　First, industrial production grew rapidly, exports accelerated quarter by quarter, and profits maintained growth.

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　　Industrial production grew rapidly. In the first three quarters, the added value of industrial enterprises above designated size increased year on year.5.8%, growth rate andone—eightApril was flat, continuing the rapid growth trend since the fourth quarter of last year. Among the three categories, the added value of manufacturing increased.6.0%The growth rate is higher than all industries above designated size.0.2Percentage points; Electricity, heat, gas and water production and supply industries grew.6.3%The growth rate is higher than all industries above designated size.0.5Percentage points; Mining industry growth2.9%. From that month,9In September, the added value of industrial enterprises above designated size increased year on year.5.4%, the growth rate is highereightSpeed up the month0.9Percentage points, in a rowfourAfter falling back last month, it recovered.

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　　Over 90% of industries and regions and over 60% of products maintained growth. In the first three quarters,41Among the three industrial categories,38The added value of each industry increased year-on-year, and the growth area was92.7%.31Among the regions,28The added value of these regions increased year-on-year, with the growth area of90.3%; Guangdong, Jiangsu, Shandong and Zhejiang have contributed more than 40% to the growth of industrial production above designated size in China. In statistics619Among the three major industrial products,399The output of this product increased year-on-year, and the growth area was64.5%.

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　　The export of industrial products is accelerating quarter by quarter. In the first three quarters, the export delivery value of industrial enterprises above designated size increased year-on-year.4.1%, growth rate andone—eightThe month is flat; The growth rates in the first, second and third quarters are respectively0.8%、5.2%、5.3%It is accelerating quarter by quarter, which strongly supports the smooth operation of the industrial economy. Among the major export industries, export delivery value, an automobile, metal products, railway, ship, aerospace industry, maintained a double-digit growth year-on-year, with the growth rates of17.1%、20.2%、23.3%. Among the major export regions, Guangdong, Jiangsu and export delivery value, Zhejiang grew rapidly year-on-year, with the growth rates of respectively5.9%、5.4%、6.3%.

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　　The profits of industrial enterprises kept growing.one—eightIn September, the operating income of industrial enterprises above designated size increased year on year.2.4%Maintain steady growth; Total profit increased year-on-year0.5%Continue the growth trend since the beginning of the year. From the perspective of industry,41Among the 10 industrial categories, there are29Profits of 20 industries increased year on year, accounting for70.7%The industry growth rate is over 70%. The profits of high-tech manufacturing industry have continued to grow rapidly.one—eightThe monthly growth rate is10.9%, higher than the industrial average above designated size.10.4个百分点。

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　　Second, the transformation and upgrading continued to advance, and the industrial economy steadily moved towards high-quality development.

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　　The industrial economic structure has been further optimized, and the role of "ballast stone" in equipment manufacturing industry has been continuously enhanced. In the first three quarters, the added value of equipment manufacturing industry above designated size increased year-on-year.7.5%, higher than all industries above designated size.1.7Percentage points. The added value of equipment manufacturing industry accounts for the proportion of all industries above designated size.33.8%, continuous19Stay in the next monththirty percentAbove, moreone—eightMonth promotion0.3A percentage point, the role of "ballast stone" has been continuously enhanced. Among them, the electronics industry grew.12.8%Since the beginning of this year, it has maintained double-digit growth and contributed to the growth of all industries above designated size.21.0%, ranking first in all major industries.

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　　The results of the "two new" policies have appeared, and related industries and products have grown rapidly. In the first three quarters, policies and measures such as large-scale equipment renewal and trade-in of consumer goods in various regions were accelerated, driving the production of related industries to improve. Driven by factors such as equipment renewal, the added value of shipbuilding and related equipment manufacturing, radio and television equipment manufacturing and communication equipment manufacturing increased respectively year-on-year.20.5%、19.8%、12.9%, sustained and rapid growth. From the perspective of products, the output of food manufacturing machinery, special equipment for agricultural products processing and special equipment for packaging increased year-on-year.38.1%、34.6%、11.8%. In terms of trade-in, driven by factors such as car scrapping and replacement subsidy policy, the output of new energy vehicles has increased.33.8%The output of charging piles related to it has increased.57.2%. Thanks to the trade-in policy of household appliances, the output of household refrigerators, room air conditioners, household refrigerators, smart TVs and other products has achieved rapid growth, with the growth rates of14.0%、8.0%、7.5%、6.7%. from9Looking at the month of June, the effect of the "two new" policies is more obvious. The output of products such as digging and shoveling transportation machinery, special packaging equipment and special equipment for agricultural products processing increased respectively year-on-year.43.7%、57.4%、36.7%, moreeightMonthly rebound8.5A,43.9A,61.7Percentage points; The output of new energy vehicles increased year-on-year48.5%, the growth rate is2023yearfiveA new high since June; The output of household freezers, room air conditioners, household refrigerators and other products achieved rapid growth, with year-on-year growth respectively.20.5%、10.7%、9.0%, the growth rate is highereightSpeed up the month16.3A,20.1A,4.3个百分点。

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　　The high-end, intelligent and green manufacturing industry continues to deepen, leading the high-quality development of industry. High-end aspect. In the first three quarters, the added value of high-tech manufacturing industries above designated size increased year on year.9.1%The growth rate is higher than all industries above designated size.3.3Percentage points. Among them, the growth rate of electronic and communication equipment manufacturing industry is12.2%, continuous11Maintain double-digit growth last month; Industries such as electronic circuit manufacturing, integrated circuit manufacturing, aerospace and equipment manufacturing increased respectively.20.8%、17.3%、12.5%. In terms of intelligence. In the first three quarters, the added value of life service industries such as intelligent unmanned aerial vehicle manufacturing and intelligent vehicle equipment manufacturing increased respectively year-on-year.56.4%、30.7%; The output of smart products such as virtual reality devices and smart phones increased year-on-year.11.0%、10.5%; Navigation, surveying and mapping, meteorology, marine special instrument manufacturing, electrical instrument manufacturing and other professional supporting industries increased respectively.39.8%、10.1%. In terms of greening. The new energy industry continues to grow. In the first three quarters, the output of charging piles, new energy vehicles and solar cells increased respectively.57.2%、33.8%、12.8%; With the increase of the supply of green materials, the output of ultra-white glass, polysilicon and monocrystalline silicon for solar energy industry increased respectively.61.2%、52.1%、29.4%.

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　　Third, the prosperity of industrial enterprises has rebounded and their business confidence has increased.

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　　The prosperity of industrial enterprises has rebounded. right10The questionnaire survey conducted by more than 10,000 industrial enterprises above designated size shows that in the third quarter, the comprehensive prosperity index of industrial enterprises above designated size rose month-on-month and year-on-year.0.3个和1.0A point. Among them,34.0%% of the enterprises think that their business conditions are good in this quarter, with a year-on-year increase.0.2个和0.9个百分点。9In June, manufacturing industryPMIfor49.8%, up from last month.0.7Percentage points; The production index is51.2%, up from last month.1.4Percentage points, back to the expansion range.

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　　企业经营信心有所增强。三季度，规模以上工业企业对四季度的综合经营状况预期指数环比、同比分别上升1.2个和1.1个点。其中，预计四季度经营状况乐观的企业占34.1%，环比、同比分别上升1.3个和0.9个百分点。调查的6万余家规模以下小微工业企业中，预计四季度生产增速加快或持平的企业比重达到84.4%，环比上升0.3个百分点。

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　　总体看，虽然外部环境依然严峻复杂，市场需求不足、企业盈利水平较低等困难仍然存在，但前三季度工业经济总体保持平稳增长。9月份，规模以上工业生产增速、PMI生产指数回升，工业企业预期企稳、信心有所增强，表明工业经济持续稳定运行仍然具有坚实基础。下阶段，要深入贯彻落实党中央决策部署，加快落实一揽子增量政策，加大助企帮扶力度，着力扩大国内需求，加快培育新质生产力，推动工业经济量增质优、行稳致远。

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　　（作者系国家统计局工业统计司司长）

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　　（原文链接：http://www.ce.cn/xwzx/gnsz/gdxw/202410/18/t20241018_39173111.shtml）

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