Today (April 7) afternoon, Beijing held a press conference on epidemic prevention and control to introduce the epidemic situation and the latest progress in epidemic prevention. A reporter at the scene asked, this round of epidemic has caused infection by overseas mail-order items. How do citizens dispose of the purchased overseas mail-order items? In this regard, Pang Xinghuo, deputy director of the Beijing Center for Disease Control and Prevention and a member of the national novel coronavirus expert group, said that there have been reports of Covid-19 nucleic acid positive in overseas mail, clothes and other articles in many places in China recently. Pang Xinghuo specially reminded the general public and friends that it is not necessary to buy less Haitao during the high-incidence period of foreign epidemics, and be careful to mail-order goods from countries and regions with high-incidence epidemics. If you have purchased goods that are not urgently needed, it is recommended to put them at room temperature for 7-14 days before processing.

Pang Xinghuo said that when receiving overseas mail or articles, you should wear masks and disposable gloves correctly, reduce direct contact, pick up the pieces at a fixed place as much as possible, and realize contactless handover. If you need to sign in person, please keep a safe distance; Dismantle the parts outdoors as far as possible, and go home without outer packaging, and treat them according to the classification of domestic garbage. If you need to take them home, you can spray or wipe the surface of mail and express delivery with chlorine-containing disinfectant or 75% alcohol to ensure that each side is completely wet, ensure all-round disinfection, and at the same time do a good job in disinfection of unpacking and transshipment tools; Mail-order items can be disinfected by disinfectants and thermal disinfection, or stored for a period of time before use; After handling mail and express delivery, you should take off gloves in time, change masks, carefully clean your hands or disinfect them, and avoid touching your mouth, eyes and nose with unclean hands.

Blue warning of severe convective weather

　　The Central Meteorological Observatory continued to issue a blue warning of severe convective weather at 06: 00 on April 5:

　　It is estimated that there will be short-term heavy precipitation in some areas of southern Anhui, northwestern Jiangxi, southeastern Hubei, northeastern and southwestern Hunan, southern Guizhou and northwestern Guangxi from 08: 00 on April 5 to 08: 00 on April 6. It is estimated that the hourly rainfall intensity can reach 30-50 mm, and the local area will reach more than 50 mm. There are hail or thunderstorms and strong winds in parts of southern Anhui, southeastern Hubei, northwestern Jiangxi, southern Hunan, south-central Guizhou and northwestern Guangxi.

　　

　　

　　　　Defense guide:

　　　　1. The government and relevant departments shall, in accordance with their duties, prepare for short-term rainstorm prevention, lightning protection and gale prevention, and the meteorological department shall prepare for artificial hail suppression;

　　　　2. Outdoor pedestrians and staff should reduce outdoor activities and pay attention to stay away from structures such as scaffolding billboards;

　　　　3. Drive poultry and livestock into places with roofs, and close doors and windows to reinforce sheds;

　　　　4. The water operations in relevant waters and passing ships shall take active measures such as returning to Hong Kong to avoid or detour navigation, pay attention to covering building materials at the construction site, and properly arrange outdoor items susceptible to heavy rain, wind and hail;

　　　　5. Check the drainage system of cities, farmland and fish ponds, and prepare for drainage and defense against disasters such as mountain torrents, landslides and mudslides.　　

---

　　Typhoon blue warning

　　The Central Meteorological Observatory issued a typhoon blue warning at 06: 00 on April 5:

　　This year’s No.4 typhoon "Mesak" (English name: Maysak；; Name source: Cambodia; Meaning of the name: a tree) was formed in the Pacific Northwest on March 28th, strengthened to super typhoon level on March 31st, and then weakened continuously. Today (5th) at 5 o’clock in the morning, its center is located on the northwest Pacific Ocean about 270 kilometers north-east of Manila, Philippines, which is 16.0 degrees north latitude and 123.0 degrees east longitude. The maximum wind force near the center is 9 (tropical storm level, 23 m/s), the lowest pressure in the center is 988 hectopascals, and the radius of the 7-level wind circle is 50-200 kilometers.

　　It is estimated that "Mesak" will move to the northwest at a speed of 20-25 kilometers per hour, and its intensity will gradually weaken. It will land in the coastal area of northeastern Luzon Island in the Philippines (8-9, 20-23 m/s), then pass through the northern part of Luzon Island, and will move into the northeastern South China Sea (7-8, 16-20 m/s) around the evening of the 5th.

　　From 08: 00 on the 5th to 08: 00 on the 6th, there will be strong winds of magnitude 7-8 in bashi channel and the northeastern part of the South China Sea, with gusts of magnitude 9 in some sea areas.

　　

　　

　　Defense guide:

　　1. The government and relevant departments shall, in accordance with their duties, do a good job in typhoon prevention and emergency rescue;

　　2. Take active measures for water operations and passing ships in relevant waters, strengthen port facilities, and prevent ships from anchoring, grounding and collision.

　　(Editor: Su Jessie)

Qin Yongcheng’s "First Oil Well" in Daqing Oilfield. Pictures are data pictures.

Qin Yongcheng (right) is with oil workers in Panjin Oilfield. Pictures are data pictures.

　　[Great motherland, unforgettable songs].

　　"Splendid rivers and mountains are picturesque, and the motherland is building a cross-horse. It’s a great honor for me to be an oil worker and travel around the world wearing an aluminum helmet … …” This heroic ode to oil workers is not only a clarion call to encourage oil workers from generation to generation to join in the construction of the motherland, but also an overall portrayal of the outstanding heroes of the working class in China. Although it was written more than half a century ago, it is still so exciting and exciting to sing today.

　　The composer Qin Yongcheng (1933— 2015) is the first generation composer trained in New China. During more than half a century’s creative career, he has created a large number of musical works with high artistic achievements and wide social influence, such as the song "I offer oil for the motherland", "Chairman Mao travels all over the motherland", My People，My Country, vocal concerto "Haiyan", symphonic poem "Two Little Cowboys" and movie music "Entrepreneurship" and "Marshal and Soldiers". He made great contributions to the music, art and education in our country all his life.

　　Three days with the "Iron Man"

　　In 1964, a notice brought Qin Yongcheng into close contact with Li Jiefu, a famous composer and president of Shenyang Conservatory of Music. It was this notice that made him have an indissoluble bond with oil workers all his life. In March this year, China Musicians Association organized some composers to experience life in Daqing Oilfield and created a batch of works reflecting oil workers. Dean Hijacking also received a notice, asking him to report to Sarthou, Heilongjiang Province on March 20th. After receiving the notice, the dean of the robbery immediately made preparations for leaving. Due to physical reasons, the college is going to find a young man to accompany the dean of the robbery to "go north". At the suggestion of the dean of the robbery, Qin Yongcheng will accompany him. Unfortunately, Qin Yongcheng was suffering from a high fever and had been in bed for three days. Upon hearing this, Dean Hijacking personally visited Qin Yongcheng’s home and told him to rest at ease for illness. In the face of this rare opportunity, Qin Yongcheng looked forward to his early recovery. Although his fever had gone down the next day, he was still very weak, and insisted on accompanying Dean Jiefu.

　　On the evening of 19th, Qin Yongcheng got his wish and boarded the train to the north. In the car, Qin Yongcheng finally put forward the question that was hidden in his heart: "Where are we going to Sarthou?" Dean Hijacking told him quietly: "Sarthou is a big oil field, called Daqing Oilfield, and it is still confidential." After moving to Daqing, Qin Yongcheng lived with many famous musicians such as Lv Ji, Qu Wei, Wang Xin, Zhang Lu and Jiefu in the guest house of Daqing Petroleum Command.

　　Since the next day, the oil field has arranged courses for musicians to introduce oil-related knowledge, from exploration and drilling to oil production and refining for ten days, with one content per day. Ten days later, the oilfield arranged for them to experience life in the first line. Qin Yongcheng, Jiefu and Wang Xin (songwriters of "Singing the Motherland") were assigned to the "1205 Hero Drilling Team" with Wang Jinxi, the "Iron Man", and lived together with the "Iron Man" for three days. During this period, Wang Jinxi told Qin Yongcheng that when he held a People’s Congress in Beijing in 1959, he saw that the buses in Beijing were in a heavy mood because of lack of oil and carrying gas bags. He also listened to him tell the story of the Daqing Petroleum Congress. In the spring of 1960, Wang Jinxi’s drilling team was in Yumen Oilfield. When it was heard that a large oil field had been discovered in the north, the whole country was going to hold a general meeting there, and immediately asked the superior to fight. They said goodbye to their relatives and boarded the train going north in their light clothes. Faced with the harsh climate, hard living and working environment, and poor equipment, oil workers shouted the loud slogan of "if you have the conditions, you should go if you don’t have the conditions" in order to get rid of the label of "poor oil" as soon as possible and break the economic blockade of western hostile forces. "When the oil workers roar, the earth will shake three times."Qin Yongcheng’s soul was strongly shocked and greatly impacted by his earth-shattering fearless revolutionary heroism. Especially in the days spent with Wang Jinxi and his heroic drilling crew, Qin Yongcheng’s understanding of oil workers has been greatly sublimated, and he has a strong emotional resonance. He is determined to create works that can reflect the spirit of oil workers to express his high respect for them.

　　A masterpiece completed in the canteen of the hostel.

　　After three days of experience, Qin Yongcheng returned to the guest house, and the Propaganda Department of the Party Committee of the Oilfield prepared a batch of lyrics reflecting the work and life of Daqing Oilfield and oil workers for them, hoping that composers would compose music for them. After the old composers had chosen the lyrics, Qin Yongcheng also chose them. At this time, a lyric jumped into his eyes, which was written by oil worker Xue Zhuguo, "I offer oil for my motherland." This first-person lyric is vivid and vivid, which vividly depicts the heroic and optimistic mood of oil workers and the fearless revolutionary spirit of fighting against the world. The more Qin Yongcheng watched it, the more he liked it. The more he watched it, the more excited he became. At this moment, he was inspired and full of thoughts. In the canteen of the hostel, he finished writing this work in just 20 minutes.

　　Inspired by the artistic conception of the lyrics, the prelude of the song adopts a fast speed, a lively and elastic rhythm, and a fluctuating melody line, like a train full of oil workers galloping in the splendid rivers and mountains of the motherland, from the northwest of the motherland to the northeast thousands of miles away. Then, the heroic song of the oil workers was introduced: "The beautiful rivers and mountains are picturesque, and the motherland is building a beautiful horse. I am honored to be an oil worker and wear an aluminum helmet to travel all over the world." The melody of the song is broad, fresh and smooth, which vividly depicts the bold spirit of oil workers and the revolutionary optimism full of pride and self-confidence. On the word "kua" of "kua steed", the melody absorbs the elements of rap music and adopts a sliding tone, which is not only in line with the rhyme of Chinese four tones but also forceful, and can better highlight the bold and hearty character of oil workers. These four sentences are lyrical paragraphs, which vividly depict the heroic fighting spirit and optimistic spirit of oil workers moving to the north and south and being at home all over the world.

　　In order to show the dauntless heroism spirit and heroic spirit of oil workers, who are "fearless of heaven, fearless of earth, and fearless of storm, thunder and lightning", Qin Yongcheng treated these two lyrics into short and powerful eight-point dotted notes and syncopated rhythm, which made the music more powerful and dynamic. At the same time, it not only forms a sharp contrast with the previous lyric paragraphs, but also lays a good foundation for the climax of the whole song that appears later.

　　The climax of the song is in the last two phrases, "I contribute oil to my motherland, where there is oil, my home is there". In order to make the climax of the song more prominent and infectious, Qin Yongcheng ingeniously treated the first beat at the beginning of this sentence as a rest, and started the word "I am" from the weak beat to highlight the word "ancestor" in the next section. Then, on the word "oil" for "offering oil", the melody adopts a circuitous upward movement, forming a large-span 10-degree interval in the range. In the last four bars of the song, Qin Yongcheng skillfully used the drawl of China’s traditional opera music for reference. It is worth mentioning that in the first draft of the work, the last four sections are not like this, but after Qin Yongcheng returned to school, he sang the work to friends and students, listened to and adopted everyone’s suggestions, and changed the original last simple melody into the current one-stop drawl. In this way, the music is more infectious and dynamic, which not only depicts the free and easy character of oil workers, but also makes the whole song end in an atmosphere full of optimism and pride. The revised work was published in the journal "Music Life" of Liaoning Branch of China Music Association, which soon became a hero’s ode to oil workers in the north and south of the motherland and inside and outside the Great Wall.

　　The only "composer of oil workers"

　　The first singer of this song, Liu Bingyi, a famous baritone singer of the former Central Orchestra, also played an important role in the promotion of this song. He and Qin Yongcheng also became attached to this song, and it was sung for 50 years. And Qin Yongcheng also started from this song, and successively created a number of excellent works reflecting oil workers. In 1973, as a key project of the Ministry of Culture, Changying filmed a feature film "Entrepreneurship" reflecting the Daqing Petroleum Congress, and specially invited Qin Yongcheng to create music for this film. Qin Yongcheng lived up to expectations, and created a number of well-known songs in his film music, such as Looking at Beijing with deep feelings, Entrepreneurial songs, and The Fragrance of Oil in Tianya Wan Li. Because of Qin Yongcheng’s outstanding contribution to the creation of oil-related music, the vast number of oil workers are familiar with the name Qin Yongcheng and affectionately call him "the composer of oil workers". In 1994, China Petroleum and Natural Gas Corporation (formerly the Ministry of Petroleum Industry) awarded Qin Yongcheng the honorary title of "composer of oil workers", and he was the only composer in China to win this honor. In 1996, China Records Corporation awarded Qin Yongcheng the "Golden Record Award" for this work, which was later included in the 20th century Chinese classics.

　　Praising the motherland and people and eulogizing the times and life are the themes of Qin Yongcheng’s life creation. It is precisely because of Qin Yongcheng’s deep patriotism, deep thoughts and feelings for the broad masses of the people, including oil workers, rich musical language based on Chinese excellent musical culture, and continuous absorption of rich nutrition and creative sources in the long-term in-depth social life that he created such immortal masterpieces represented by "I Contribute Oil to the Motherland", which are full of positive energy and the main theme of the times, and have high artistic value and appeal to both refined and popular tastes. (Author: Wei Huang, former vice president and second-level professor of Shenyang Conservatory of Music)

Cctv news Once, he dedicated himself to the country, and his iron will showed the true colors of soldiers; Today, he is physically disabled and determined, and he has retired as a "poverty fighter." He is Chen Zhikun. He was drafted into the army in 1981. Unfortunately, he was injured in the battle and won the second class merit. He could have enjoyed the preferential treatment of the state for a lifetime, but he was glowing on the road to entrepreneurship. He believes that "the body can’t move, the brain can move, and it can make a little contribution to society."

After Chen Zhikun retired from the army, Zhenning County, Anshun City, Guizhou Province, provided him with a house of more than 90 square meters in accordance with the regulations of the state on special care for civil affairs, and he can also be supported by the state for life. However, he resolutely rejected the kindness of the organization to arrange work for him and decided to start his own business.

Chen Zhikun had motorcycle maintenance technology when he was in the army. After returning home, he re-learned this craft with reference to a large number of materials, and he quickly became a master in the industry while learning and practicing. In 1994, Chen Zhikun opened a motorcycle repair department. Apart from excellent repair technology and low cost, he also recruited unemployed and disabled young people in society to learn repair technology for free. It didn’t take long for many apprentices in Chen Zhikun to become one of the few million households at that time with the good skills they learned.

With years of hard work, Chen Zhikun has created a miracle of entrepreneurship for the disabled. At that time, Chen Zhikun’s hometown was still poor, and he was deeply disturbed. He decided to drive his neighbors to get rich together. So, Chen Zhikun said goodbye to his family with a start-up capital of 500,000 yuan and returned to Qishan Village, Shaoxing City, Zhejiang Province, where he was born and raised.

After discussing with the village cadres, he founded the 2,000-square-meter "Rongjun Breeding Demonstration Farm in Qishan Village, Machang Township, Zhenning Autonomous County" to attract many poor households in the village to work in the farm. In 2007, Chen Zhikun founded Guizhou Qianningxiang Green Food Development Co., Ltd., focusing on breeding sows and fattening pigs, and in 2008, he founded Rongjun Breeding Cooperative. Under the leadership of Chen Zhikun, a through-train system of breeding, storage, transportation and sales has been formed, and more than 40 technical backbones have been trained. In training, purchasing breeding pigs, breeding, epidemic prevention, technical guidance, purchase and sales, he gave 40% of his annual profits to veterans and disabled people engaged in farming.

Feng Zufang is one of the villagers that Chen Zhikun helped. Feng Zufang was engaged in raising pigs before he joined Chen Zhikun’s company, but because he didn’t know scientific breeding technology, he could only make ends meet and sometimes even lost money. After joining the breeding association, her family’s economic income has increased significantly. At most, she can slaughter about 100 pigs a year, with an annual income of not less than 20,000 yuan.

Chen Zhikun "taught people to fish" through his own technical ability, so that those poor people can completely end the poverty situation. He has trained more than 8,000 breeding technicians for free, and inspired more than 9,000 farmers to practice scientific pig raising.

He is a fearless soldier on the battlefield; In starting a business, he is an entrepreneur who cares about his fellow villagers and elders, veterans and disabled people. He showed us the inner qualities of a soldier with his actions. Let’s say thank you to him!

Through ten groups of questions and answers, this paper gives you the function and application of popular science stem cells, and shows you the important position of stem cell therapy in modern medical care.

Mother, the pilot of the boat of life, not only gave birth to us, but also promoted the reproduction of mankind. She is a great inheritor of life and a transmitter of love.

Cells, the weavers of the web of life, constitute the cornerstone of the human body, which is a miracle exhibitor with various forms and complicated functions.

The human body is a magnificent movement interwoven with countless cells, the harmonious resonance of 240 kinds and 60 trillion cells, and the subtle fusion of 4 major organizations, 36 organs and 8 major systems.

She is a special cell, but also the guardian of the source of life. She can regenerate new cells, replace aging cells and repair damaged tissues and organs. She is the mother of the cell world.

This kind of cell is the root of our life-stem cells.

With the progress of science, stem cell research has become one of the most advanced and active research directions in the global medical field.

However, for the general public, what exactly are stem cells? What does it do? What kind of people are suitable for repair intervention through stem cells? What are the risks even in treatment? This article will help you understand these questions easily through ten groups of questions and answers.

Ten questions and answers about stem cells

01

What are stem cells?

Stem cells are cells with self-renewal function and multi-directional differentiation ability.

Under certain conditions, these cells can differentiate into more than 220 different functional cells in human body. Because of its remarkable homing effect, stem cells can repair and replace damaged cells and promote organ regeneration. They are the basic cells that constitute various tissues and organs of the human body, so they are known as "the source of life" and are often called "universal cells" in the medical field.

02

What are the classifications of stem cells?

Scientific research shows that stem cells exist not only in embryos, but also in adults, which can be extracted from cord blood, umbilical cord, placenta, bone marrow, fat and other tissues.

Stem cells are divided into totipotent stem cells, pluripotent stem cells and unipotent stem cells according to their extensive differentiation ability.

Stem cells can be divided into embryonic stem cells and adult stem cells according to their stages of embryonic development.

According to the tissue type of stem cell differentiation, it can be divided into hematopoietic stem cells and mesenchymal stem cells.

03

What is stem cell therapy?

"Stem cell therapy" refers to a medical intervention that extracts stem cells from patients or uses other stem cells, cultivates them under laboratory conditions, and then transfuses them into patients through specific transplantation techniques, so as to repair the cells and tissues that have lost their functions, thus promoting their regeneration and improving their symptoms. At present, hematopoietic stem cells and mesenchymal stem cells are widely used in clinic.

04

What is the difference between autologous and allogeneic stem cells?

Autologous stem cells are derived from patients themselves, which have perfect tissue compatibility, no need for matching, high utilization rate of transplanted cells and no rejection.

Allogeneic stem cells are derived from individuals other than patients and have low immunogenicity. Autologous stem cells are not recommended for people with infectious diseases, major genetic diseases or other health problems.

05

How can stem cells be used to treat diseases?

Cells are the basic unit of life. Human life is accompanied by the process of self-replication and differentiation of stem cells from birth to growth. The ability of stem cells to treat diseases mainly stems from their biological characteristics, which include:

The ability of long-term survival and continuous self-replication;

It can differentiate across different lines and germ layers, showing high plasticity;

And its chemical tendency, that is, homing effect, provides an important biological basis for cell therapy.

06

Is stem cell therapy risky?

Compared with conventional drug therapy, stem cell therapy is considered safer and has fewer side effects. But this does not mean that the risk is zero. Looking at stem cell therapy objectively, the following are some main risks of stem cell therapy:

Tumor development: If stem cells divide or differentiate into abnormal cells uncontrollably, it may lead to cancer. This mainly applies to embryonic or fetal stem cells, or reprogrammed stem cells, because the risk is based on their pluripotency.

Immune rejection: The body may regard foreign stem cells as a threat and attack them, leading to inflammation and injury. This is more likely to happen in hematopoietic stem cells (HSC).

Infection or complications related to invasive medical procedures: Stem cell therapy may lead to infection or complications related to invasive medical procedures.

Drug interaction: Stem cell therapy may have unpredictable interactions with other drugs taken by patients, which may lead to adverse drug interactions.

Unconfirmed or untested stem cell therapy: There is also the risk that unscrupulous practitioners provide unconfirmed or untested stem cell therapy, which may be unsafe or effective.

The effect of treatment is uncertain: patients should also realize that stem cell therapy does not guarantee a cure, and in some cases, it may not be effective at all. Stem cell therapy may not provide lasting results, and patients may need additional treatment.

It should be noted that these risks may be different due to individual differences, treatment methods, stem cell types and other factors. Before receiving stem cell therapy, patients should fully discuss these risks with doctors and weigh the potential benefits and risks of treatment.

07

What diseases can stem cell therapy treat?

Stem cell therapy is mainly used in the fields of treatment, health care and beauty, and it is also used to improve some refractory diseases.

Heart disease: Stem cells can regenerate damaged heart cells and maintain the health and vitality of the heart through a specific process of induced differentiation in the treatment of heart disease.

Prevention and treatment of Alzheimer’s disease: Injecting induced differentiated stem cells can replace aging brain cells and improve cognitive function.

Treatment of liver cirrhosis: generate liver cells through differentiation, and promote the regeneration and repair of liver cells.

Cancer treatment: Directionally differentiated stem cells can enhance the body’s immune function and help fight tumors.

Treatment of premature ovarian failure: Stem cell therapy can restore ovarian function, promote the repair of damaged tissues, improve ovarian microenvironment, enhance reproductive capacity, prevent follicular atresia and promote follicular renewal.

Male hypofunction: Stem cell therapy can repair the aging of reproductive system, improve sexual function, maintain the balance of sex hormones, reduce nocturia, relieve the symptoms of prostatic hyperplasia, and help prevent prostate hypertrophy and other problems.

Enhance muscle function: with the increase of age, muscle function weakens, strength and relaxation function decline, and the body is bloated. Stem cell therapy can improve muscle function, enhance strength, improve body shape and show youthfulness.

08

What is the effect of stem cell therapy?

Stem cell therapy can be carried out by systemic infusion or fixed-point intervention. Clinicians adopt appropriate cell types and treatment strategies according to patients’ health status and disease needs.

Because this treatment can directly intervene in the cause of disease, avoid other physical injuries that may be caused by drugs and surgery, and help regulate the sub-health state, the effect is usually not limited to treating diseases, but also improving the overall function.

09

Is there an age limit for stem cell transfusion?

Traditionally, some types of stem cell transplantation, such as allogeneic bone marrow transplantation, often have age restrictions, and it is usually recommended to be 50 years old or under 45 years old. However, with the progress of medical technology, this limitation is being broken.

For example, it has been reported that a 71-year-old patient successfully received autologous hematopoietic stem cell transplantation, and a 69-year-old woman also successfully received her son’s hematopoietic stem cell transplantation.

These cases show that under proper medical conditions and monitoring, elderly patients may also successfully receive stem cell transfusion therapy, which proves that the age limit is gradually relaxing.

10

What are the taboo populations of stem cells?

Patients with advanced malignant brain tumors, especially brain tumors;

Patients with shock or general failure with abnormal vital signs (requiring disease correction) and those who do not cooperate with the examination;

Patients with heart, lung, liver, kidney and other important organ dysfunction (multiple organ dysfunction syndrome);

Patients with dysfunction of coagulation mechanism;

Patients with severe local infection;

Patients with positive serological results (such as HIV, hepatitis B, syphilis, etc.);

People with high allergic constitution or severe allergic history;

People with nervous system diseases or diseases that have not been diagnosed;

This group is in a special situation and has uncontrollable risks, so it needs careful diagnosis and treatment.

Write it at the end

Stem cells have excellent regeneration and repair functions, and these abilities will gradually weaken with age. Therefore, it is an increasingly popular choice to store healthy stem cells as early as possible, which will provide the possibility for future health management and disease treatment.

The 21st century will be the era of cell therapy, and the application of stem cells and immune cells is expected to play an important role in clinical treatment.

However, at present, except for the mature clinical application of hematopoietic stem cell transplantation, other types of stem cell therapy are mostly in the research stage, and strictly designed clinical trials are needed to prove their clinical advantages, safety and effectiveness, which need further study.

Moreover, non-compliant and eager stem cell therapy and research not only threaten the safety of patients, but also hinder the improvement of stem cell therapy and its research level, which needs the attention of legal supervision, and patients with hope in stem cell therapy should also be alert to fraud and pay attention to its development and related policies and regulations.

Original title: "Why do you call her" the mother of cells ":Ten questions and ten answers about stem cells, and learn about her magic with you"

Read the original text

　　How long has it been since you made a confession? It is said that companionship is the longest confession. When you set foot on the way home for the Spring Festival, they can’t. Light this lamp and listen to their confession … …

　　"I am confident that SARS will not happen again."

　　Zhong Nanshan is on the high-speed train dining car to Wuhan. source map

　　17 years ago, in the face of SARS,

　　He said, "Send all the seriously ill patients to me."

　　When novel coronavirus attacked,

　　Academician Zhong Nanshan, 84, rushed to the forefront of the fight against the epidemic.

　　From Guangzhou to Wuhan and then to Beijing,

　　Understand the epidemic situation on the spot and study the prevention and control plan … …

　　Along with countless doctors,

　　Into this war without smoke.

　　User comments screenshot. source map

　　"No reward, no matter life or death"

　　Wuhan doctor’s circle of friends. source map

　　When the epidemic spread,

　　They took the initiative to apply for the first line of treatment.

　　The second batch of voluntary registration in tongji hospital is full.

　　At 1 am, they are still fighting!

　　Hold on for 432 hours,

　　No complaints, no fear of risks!

　　User comments screenshot. source map

　　"You protect the country, I protect you."

　　Military wife Liu Hangyan took her daughter Hu Die to visit her husband Hu Jiajun in Xinjiang. source map

　　The journey is 4354 kilometers,

　　It lasted 49 hours and 45 minutes.

　　To the Pamirs at an altitude of 3,515 meters,

　　Liu Hangyan, the military wife, took her 2-year-old daughter Hu Die.

　　Go to Xinjiang to visit her husband Hu Jiajun.

　　Press countless tears into a smile to see you,

　　Across Qian Shan,

　　Just for a reunion of the Spring Festival.

　　User comments screenshot. source map

　　"I can’t accompany you, mom must take care of herself."

　　"Iceman" Zhao Zuoqian. source map

　　A spade, a spade,

　　A pickaxe, a pickaxe,

　　Taihang Mountain Tunnel at minus ten degrees,

　　China Railway Zhengzhou Bureau

　　Zhao Zuoqian, the "Iceman" in Yueshan Works Section,

　　Carrying a 15-pound long steel drill,

　　Race against time to remove the ice on the tunnel wall,

　　Ensure driving safety.

　　User comments screenshot. source map

　　"I can’t leave, there are sick children waiting for me."

　　Doctor Lu Shengmei. source map

　　In a small town in northern Shaanxi deep in the Loess Plateau,

　　76-year-old Lu Shengmei,

　　Still on the way to a free clinic.

　　More than 50 years ago, she left Beijing.

　　Take root here silently,

　　For the backward small county.

　　Established the first formal pediatrics,

　　Protect the health of thousands of infants.

　　User comments screenshot. source map

　　"Son, when you grow up, you will understand Dad."

　　Zhao Lin, deputy detachment leader of anti-drug detachment of Kunming Railway Public Security Bureau. Photo courtesy of Kunming Railway Public Security Bureau

　　633.2 kilograms of drugs were seized,

　　1398 drug-related criminal suspects were arrested.

　　24 years as a police officer,

　　Anti-drug policeman Zhao Lin is at the border,

　　Drugs are flowing around,

　　In the face of vicious drug dealers,

　　He was never afraid.

　　But absent from the growth of his son, he was full of debt.

　　User comments screenshot. source map

　　"The station is my other home, and the passengers are my family."

　　Yu Xiaofei, passenger attendant at Guozhen Station, Baoji Locomotive Depot, Xi ‘an Bureau Group Company. source map

　　At 20: 11,

　　At Guozhen Station in Baoji Town,

　　Yu Xiaofei, the attendant, watched the last train leave the station.

　　Stick to the Spring Festival in 8 years,

　　Send one passenger safely home,

　　And home 1521 kilometers away,

　　But it became a distant place that she could not reach.

　　User comments screenshot. source map

　　"If a family is not round, it will be safe when it is round."

　　Li Yufeng, captain of the Special Operations Brigade of a detachment of the Armed Police Heilongjiang Corps. source map

　　After 18 years in the army,

　　Countless times facing the test of life and death,

　　The choice of Li Yufeng, the special commander of the armed police.

　　Are born to die.

　　When all families are reunited,

　　Like thousands of soldiers in China,

　　Still standing guard for the country.

　　User comments screenshot. source map

　　Confession, to the relatives who will accompany you for life. Confession to 9.6 million square kilometers of land. How many families can’t be reunited, there are as many heart-wrenching confessions.

　　Ordinary makes great, and the way they struggle and stick to it is the best confession for their family and country.

　　The old year is about to go away, but our love is endless in confession! (China Youth Network reporter Li Huihui Yang Yue correspondent Wang Haibo Zhang Baozhong Wang Zhanjun Li Yan)

　　Multiple social apps can still be used normally without "real-name authentication". Insiders suggest that the youth mode should be turned on by default.

　　Recently, many netizens found and reported that some dating software is not strict with the use of minors. The Beijing Youth Daily reporter found that when using multiple strangers’ dating software, there is no need for real-name authentication, and minors can use these strangers’ social software "unimpeded". It is particularly noteworthy that in terms of function, there is no difference between unauthenticated accounts and other accounts, and accounts without real-name authentication can also purchase adult products at will. In this regard, many people in the industry have suggested that the youth mode can be turned on by default when the user does not log in with an ID card.

　　find

　　Multiple social App users can also be rewarded without real-name authentication.

　　The reporter of Beiqing Daily recently found that many social apps, such as soul, Detective, Momo, etc., can be used normally by simply choosing to log in with WeChat or mobile phone number without "real-name authentication".

　　These platforms all suggest that users must be over 18 years old when registering. For example, after soul registers, users need to choose the date of birth, but users can enter the interface without hindrance by filling in a date over 18 years old at will. Among them, soul needs to use a virtual avatar, and exploration and Momo need to add a real and clear avatar.

　　In the process of use, the above App will send a pop-up window in teenager mode to the user. The reporter of Beiqing Daily noticed that the youth mode entering Soul needs real-name authentication, and people’s faces will be dynamically recognized during the authentication process. After the tester enters his real name information, he can’t enter the teenager mode again. The teenage mode of exploring and momo is to set the password directly.

　　In view of the fact that it can be used normally without real-name authentication, Momo customer service responded: "Some functions need real-name use." When asked which functions will be affected by not having a real name, the customer service did not give a positive answer. In addition, regarding whether the real name will restrict consumption, the customer service said: "No real name will not restrict consumption."

　　When using the live reward function of Detective and Momo, even the account without real-name authentication will automatically jump to WeChat or Alipay.

　　In terms of recharge, none of the above three softwares has relevant restrictions or secondary verification for minors. And there is no real name account and unlimited consumption, which can recharge the highest amount of soul coins, exploration coins, momo coins and VIP recharge.

　　experience

　　Push content is undifferentiated, making friends and shopping are not affected.

　　The reporter of Beiqing Daily used an account without real-name authentication on a dating software, and marked "the second day" in the introduction. After searching for keywords such as "making friends in junior high school", "sexy underwear" and "adult products" on the home page, a lot of related push content appeared. The purchase of goods can automatically jump to WeChat or Alipay. In other words, if minors are not authenticated in this platform, it will not affect their use.

　　After several keyword searches, Beiqing Daily reporter used the test account to open the above-mentioned dating software again, and the homepage push also became the corresponding content related to keywords, in which minor dating also appeared directly and many times. In the shopping column, most of the products pushed also meet the previous keywords.

　　In the actual measurement, the reporter of Beiqing Daily also found that there are multiple video platforms in the youth protection mode, and the platforms will impose restrictions on young users in terms of content, usage duration and consumption.

　　For example, the daily use time should not exceed 40 minutes, and it is forbidden to use the software from the evening to the next morning, and it is impossible to open or watch the live broadcast, reward, recharge, cash withdrawal and so on. For example, a survey shows that in the youth mode, except for the functions of mobile phone recharge and city service, other functions of life service, transportation and shopping consumption are all disabled, while the functions of financial management are directly hidden. Aauto Quicker and Tik Tok, short video applications, banned teenagers from watching live broadcasts, which fundamentally prevented the risk of teenagers’ recharge and reward. Tik Tok also closed Tik Tok Mall. Video platforms Iqiyi, Tencent, Youku and Mango TV have closed the membership center and all other consumption channels such as financial welfare and games. Bilibili has also closed consumer operations such as membership purchase and top-up rewards.

　　suggestion

　　Directly open the youth mode for the unauthenticated netizen platform.

　　In response to the measured results of the reporter of Beiqing Daily, Professor Shang Jianhui, deputy dean of the School of Journalism and Communication of Hebei University, believes that the platform practice that has not yet imposed restrictions on young users does not conform to the norms. "According to the explicit requirements of the Regulations on the Protection of Minors’ Network (Draft for Comment) and the Regulations on the Protection of Children’s Personal Information Network, the network platform should formulate special rules and user agreements for the protection of children’s personal information. Therefore, this practice of the platform should be improved, otherwise it may cause harm such as premature maturity of children and deception of the network. "

　　Professor Shang suggested how to improve the platform’s protection measures for minors. "At present, there are some voices in academic circles. The index system of minors’ network protection includes 19 indicators in six dimensions, including information prompt, technical protection, anti-addiction (comprehensive) management, emergency complaint and reporting mechanism, privacy and personal information protection system, scientific popularization and publicity and education."

　　"Technical protection, information tips, scientific popularization and publicity and education are the weak links in the protection of minors on the Internet platform. The platform should first strengthen technical security protection and realize standardized management of the platform; Secondly, construct an omni-directional information prompt matrix to optimize the use environment of minors; Furthermore, practice the concept of multi-knowledge inclusiveness and do a good job in popular science and publicity and education; Finally, improve the youth model and enrich the content pool for minors. " Professor Shang said.

　　Some operators who did not want to be named told the reporter of Beiqing Daily that "registering with a mobile phone number does not mean real-name authentication. Operators will not synchronize all users’ personal information to all platforms at will. It is not excluded that operators cooperate with some larger platforms to authorize the platforms to identify information through mobile phone numbers, but only if both parties sign an agreement to ensure the other party’s safe storage and standardized use of personal information. Therefore, it cannot be said that registering with a real-name mobile phone number is equivalent to real-name authentication. "

　　Earlier, Jiang Yaodong, member of Chinese People’s Political Consultative Conference and former vice president of China University of Mining and Technology (Beijing), also suggested that "for users who have not been authenticated, the platform can default the user to enter the youth mode, which can protect minors from browsing age-appropriate content to the greatest extent."

　　interlinkage

　　According to public data, in 2021, the number of underage netizens in China reached 191 million, and the Internet penetration rate of minors reached 96.8%. According to a survey released by Beijing Internet Court, from June 2022 to May 2023, Beijing Internet Court accepted a total of 143 civil disputes involving minors, and the number of cases increased year by year, with game recharge and live rewards accounting for the largest proportion. Among them, the phenomenon that minors involved in litigation evade family supervision and anti-addiction measures is more prominent, and most minors evade family supervision and platform authentication measures. At the same time, minors are easily influenced by bad information. Some minors use the Internet to browse pornographic, bloody and violent bad content, and some minors are influenced by the online war and the "network water army" and learn to imitate bad online behavior.

　　Text/reporter Wen Wei Intern Li Yujie

    The column "Insight into New Trends and New Possibilities of Pharmacy" is a special program "Pharmacy Consultation" for the seventh anniversary of Ali Health Pharmacy jointly produced by Ali Health and Cyberblue. The purpose of this paper is to explore the new trend of medical and health industry in the new era from the perspective of pharmaceutical companies’ first site, and to discuss how pharmaceutical companies and Internet medical platforms can jointly build an ecology to provide users with more comprehensive, professional and convenient new ways of health services under the changing industry and around the changing needs of users.

    Today, we will review AstraZeneca’s innovative practice of deepening the China market for 30 years, and discuss the "entrepreneurial history" of this multinational pharmaceutical company in China from two dimensions of "digitalization" and "ecological circle".

    "Taking patients as the center and technology as the driving force, we will jointly explore the construction of a healthy and innovative ecology. While realizing digital medical care, we will help improve the integrated diagnosis and treatment and the whole course management plan, bringing new ideas for chronic disease management, primary care and multi-scene medical services. This is the fifth year of AstraZeneca’s health cooperation with Ali. In the year, AstraZeneca’s global executive vice president, international business and China President Chloe Wang sent a message to Ali Health.

    Behind this message, on the one hand, AstraZeneca’s positive layout in the digital field, and on the other hand, its interpretation in innovative ecological cooperation. These are the two main ideas that AstraZeneca cultivated in the China market for a long time.

    When talking about AstraZeneca, apart from its important role in tumor, cardiovascular and respiratory treatment, we will also mention AstraZeneca’s attitude of embracing the China market and focusing on the China market: in the past 30 years, AstraZeneca has embarked on its own path from product introduction to overweight manufacturing to the construction of innovative ecology.

    AstraZeneca embraced the China market vigorously, and the China market also gave AstraZeneca a good feedback-for a long time, AstraZeneca’s sales in China were among the best among multinational pharmaceutical companies.

    On the 30th birthday just past, AstraZeneca said that it would continue to "bring in" and "go out" simultaneously, push China’s innovation to the world and continue to embrace the China market.

    "Embrace the China market" is not just a slogan. How did AstraZeneca land? We try to deconstruct from two aspects: "digitalization" and "ecological circle".

    AstraZeneca’s Innovation Ecosphere

    As a leading pharmaceutical company in the world, AstraZeneca’s product innovation has always been at the forefront of the world. Although there are not a few multinational pharmaceutical companies with strong products entering the China market, AstraZeneca is the most outstanding in terms of volume and growth rate.

    Behind this is that AstraZeneca, on the basis of its rich treatment methods, has long been committed to promoting the mutually beneficial integration of global and local innovations in China: identifying the connection points between enterprises and policies and market trends, and the advantages of China’s supply chain, and constantly innovating the upstream and downstream cooperation models.

    In diagnosis, the industry trend of accurate detection should be followed. AstraZeneca and its partners announced the establishment of the MET HER2 Accurate Diagnosis Alliance to jointly build the capabilities in disease prevention and early screening, personalized treatment plan and so on.

    In terms of treatment, with the rise of local innovation in China, AstraZeneca actively explores ways to cooperate with local pharmaceutical companies with an open mind on its own product pipeline array. Last year, AstraZeneca and Unacon started cooperation on oxitinib. As a part of the long-term project of "lung cancer targeted joint scientific research cooperation", AstraZeneca is trying to link the clinical strength of local pharmaceutical companies to better improve the survival and benefit of lung cancer patients in China.

    In disease management, AstraZeneca starts from the scene of field diagnosis and treatment, helps medical institutions to build a bridge between doctors and patients, and provides solutions such as full course management and integrated diagnosis and treatment. AstraZeneca has signed strategic cooperation agreements with a number of medical groups to jointly integrate high-quality resources and strengthen the role of non-public medical care in China’s current medical system.

    From diagnosis to treatment to management, AstraZeneca’s strategic layout and cooperative ecology cover the complete treatment journey of patients.

    In addition to the traditional health industry chain, AstraZeneca is also actively embracing the new format of the health industry.

    In May this year, AstraZeneca and Ali Health jointly built a cardiovascular disease education and rehabilitation platform to provide customized and innovative digital health management services for patients with chronic diseases. Some consumption scenes of chronic diseases have been moved online, and through digital means, patients’ disease cognition and course management efficiency have been improved.

    "By building the" Troika "of innovative ecosystems such as China Smart Health Innovation Center (CCiC), International Life Science Innovation Park (iCampus) and AstraZeneca Zhongjin Medical Industry Fund (AZ-CICC Fund), AstraZeneca has joined hands with local pharmaceutical innovation forces in China to continuously and deeply build an international healthy innovation ecosystem." Zhu Lixuan, vice president of AstraZeneca China, head of the Digitalization and Business Innovation Department and the Business Strategy and Operational Excellence Department, explained the concept of the ecosphere.

    She said that AstraZeneca very much hopes to find an ecosystem partner who is also patient-centered and can complement each other’s business. The advantages of AstraZeneca in the field of medicine will be combined with excellent enterprises in the fields of equipment, special medical food, mental health and sports to achieve cooperation covering many aspects of the whole course management.

    Previously, foreign pharmaceutical companies relied on advanced products to meet the health needs of their stocks in the China market. Nowadays, the growth of the pharmaceutical industry needs everyone to make the cake in the market bigger together. The creation of AstraZeneca innovation ecosystem is the process of making the cake bigger with partners.

    Digitally open up the whole course management

    If the "ecological circle" is to improve the service experience of patients in the whole diagnosis and treatment process, then "digitalization" is a powerful tool to improve the medical and health service experience.

    The combination of "smart medical care" and "patient-centered" requires all parties in the medical system to cooperate through digital tools, provide continuous, convenient and high-quality services for patients, and track, record and guide each stage of the course.

    In this regard, AstraZeneca’s strategy is to focus on subdividing the treatment field, explore a set of landing models, and copy them to other fields.

    In terms of business, AstraZeneca supports associations, hospitals and experts to launch an innovative diagnosis and treatment system integrating screening, diagnosis, treatment and management; A digital management platform has been established in many fields, such as tumor, cardiovascular disease and chronic disease, so that every link of standardized treatment can be standardized, and standardized diagnosis and treatment data can be accumulated through standardized electronic medical records and quality control management in diagnosis and treatment.

    Faced with a series of problems such as uneven supply of medical resources in the low-end market and complicated process of patient diagnosis and treatment, AstraZeneca has applied for digital solutions such as remote consultation, multidisciplinary diagnosis and treatment (MDT) and distance academic training and education, and is committed to improving the quality of diagnosis and treatment in various places.

    In terms of channels, AstraZeneca also spared no effort to give full play to the advantages of digitalization.

    Grass-roots business has been difficult for many pharmaceutical companies to cover because of its wide distribution and low service efficiency. This is what AstraZeneca has been trying to overcome since it entered the China market. AstraZeneca has cooperated with many local e-commerce companies and Internet medical platforms, such as Ali Health, to create an online and offline integrated health service scene, which improves the accessibility of medical care and patient medication. In addition, AstraZeneca has specially built a grassroots business team to actively improve the medical service experience of patients in third-and fourth-tier cities.

    The innovation of digital diagnosis and treatment (service) and the improvement of infrastructure in distribution channels (tools) make AstraZeneca closer and closer to its goal in the grassroots market.

    In addition, based on the established standardized treatment database, AstraZeneca is also exploring the empowerment of product research and conducting comprehensive digital medical exploration and research.

    At the same time, AstraZeneca is also using some cutting-edge digital tools to empower the whole process.

    Shenrui Medical, a participating enterprise of AstraZeneca Zhongjin Medical Industry Fund, is one of the pioneers in the field of AI medical care in China. Its Dr.Wise AI medical auxiliary diagnosis system uses international cutting-edge technology to make artificial intelligence medical image diagnosis reach the advanced level, and it is in the forefront of the industry in the accurate diagnosis of diseases in various systems, which can provide clinical suggestions for doctors to make further diagnosis and treatment decisions. At present, the system is widely used in decision-making and follow-up of early screening of lung cancer, early screening of breast cancer and auxiliary assessment of stroke, which effectively helps to improve the efficiency of doctors’ diagnosis and treatment and reduce the rate of misdiagnosis and missed diagnosis.

    Digitalization is not a concept, but for "usefulness".

    "Realizing data insight and closed loop at each key node is the key to the success of digital transformation of pharmaceutical companies. But we can’t digitize for the sake of digitization. All digital transformations must be patient-centered, empower doctors and patients through digital innovation, improve the efficiency of disease management, and ultimately benefit patients. " Zhu Lixuan said this.

    Multinational pharmaceutical companies start businesses in China.

    Health is an eternal demand. No matter how the external environment changes, consumers are willing to invest in high-quality health needs.

    In the field of health consumption, there are both commodity consumption and service consumption, such as online consultation and telemedicine; It not only integrates cutting-edge scientific and technological innovations, but also integrates fine and intimate health guidance. Consumer demand is diversified, personalized and multi-level, and the update and upgrade speed is faster.

    Under the diversified consumer demand, AstraZeneca is exploring how to match the needs of China patients with more drugs and solutions.

    At first, AstraZeneca introduced abundant therapeutic tools to China. Since then, AstraZeneca has continued to expand the localization process in the supply chain to improve the accessibility of drugs at lower production costs.

    Nowadays, when the demand for health consumption is more and more diversified, from treatment to service, from effectiveness to accessibility, from the north to the low-end market, from simply eliminating illness to improving the whole process experience … AstraZeneca meets these diversified needs one by one. The process of finding the demand and satisfying it is a process of starting a business.

    Talking about AstraZeneca’s future layout of China market, Zhu Lizuan shared: "On the basis of the continuous improvement of agglomeration effect and mode maturity, the’ Troika’ of innovation centers, innovation parks and funds is expected to further strengthen their mutual coupling and driving operation modes and help more local innovation achievements to land. In the future, AstraZeneca will also promote more innovative models, innovative enterprises and innovative achievements in China to the world stage by building bridges to the sea, and vigorously promote the global layout and development of China enterprises. " Zhu Lixuan mentioned.

District, county (city) Construction Bureau, the relevant units directly under the Committee, the construction and supervision enterprises:

In order to further promote the standardization and standardization of safety and civilized construction management of construction projects in our city, and improve the management level of construction sites, according to the Implementation Measures for Excellent Site Evaluation of Standardization Management of Construction Safety in Zhejiang Province by the Provincial Department of Housing and Construction, we have revised the original Management Measures for Standardized Model Sites of Construction Projects in Hangzhou, which are hereby promulgated, please implement them carefully.

Hangzhou Urban and Rural Construction Committee

June 16, 2020

Standardized management of construction safety in Hangzhou cityMeasures for the Administration of Excellent Site Selection

Chapter I General Provisions

Article 1 In order to further improve the management level of safe and civilized construction of construction projects in the whole city and standardize the selection and management of excellent sites for standardized management of safe and civilized construction, these management measures are formulated in accordance with the provisions of People’s Republic of China (PRC) Construction Law, Regulations on Safety Production Management of Construction Projects, Several Opinions of the Ministry of Housing and Urban-Rural Development on Promoting the Development and Reform of Construction Industry, Implementation Measures for Evaluation of Excellent Sites for Standardized Management of Construction Safety Production in Zhejiang Province and other laws, regulations and documents, combined with the actual situation of Hangzhou.

Article 2 These Measures shall apply to newly built, expanded and rebuilt houses, municipal infrastructure projects and urban rail transit projects within this Municipality.

Article 3 The Hangzhou Urban and Rural Construction Committee (hereinafter referred to as the Municipal Construction Committee) shall be responsible for organizing and implementing the selection and management of excellent construction sites for standardized production safety management of construction projects in Hangzhou. City Construction Engineering Quality and Safety Supervision Station, District and County (city) Construction Bureau (or its entrusted supervision and management institutions) (hereinafter collectively referred to as "supervision institutions") are responsible for supervising the project process evaluation and report selection.

Article 4 The selection of excellent municipal standardization sites shall be conducted by combining process evaluation, expert review and jury review. The supervision organization is responsible for the process evaluation and forms the process evaluation opinions; Expert review by the expert group to review the application materials, daily management and evaluation materials of enterprises, and put forward review and evaluation opinions; Jury review by the jury according to the process evaluation opinions, expert group review opinions to review, vote to determine the candidate list of winning projects.

Fifth city standardized excellent site evaluation number of total control, merit selection. The allocation of reporting indicators shall be based on the principle of territoriality where the project is located, and shall be allocated and adjusted according to the following factors:

(a) the scale of the project construction and the completion of the project in that year;

(two) according to the overall level of production safety management, especially the annual production safety situation in each district;

(3) Give due consideration to regional and professional balance.

Chapter II Application Conditions

Article 6 The excellent site of city standardization shall be selected once a year on the basis of voluntary declaration by enterprises and recommendation by supervision institutions. The projects participating in the selection of city standard chemical sites shall have the following scales:

1. Residential groups with a single residential project of more than 4,000 square meters and a construction area of more than 15,000 square meters, and supporting villas of more than 5,000 square meters;

2. For public buildings with a construction area of more than 5,000 square meters, the public construction area of counties (cities) shall not be less than 4,000 square meters. Renovation works of antique buildings of more than 600 square meters or major ancient buildings and garden buildings of national key cultural relics protection units;

3. Installation of industrial equipment with independent devices with a project cost of more than 15 million (including 15 million);

4. The construction cost of general municipal infrastructure projects is more than 15 million (including 15 million), and the construction cost of counties (cities) is more than 10 million (including 10 million);

5. Station, depot, comprehensive base, control center, section, tunnel and elevated unit projects with a cost of 50 million yuan or more in urban rail transit projects; Main track project with a cost of more than 50 million yuan;

6. The construction cost of tunnels, sewage treatment plants, water purification plants, plazas and other construction projects is more than 30 million (including 30 million), and the construction cost of county (city) construction projects is more than 20 million (including 20 million). In the square project, the square civil construction area should be no less than 50% of the total area, and the engineering quantity should be no less than 60% of the total;

7. The project scale does not meet the above requirements, but it has remarkable economic, social and environmental benefits, and has made outstanding achievements in creation.

Article 7 An enterprise that declares an excellent site for city standardization must meet the following conditions:

1 registered construction enterprises in this Municipality or foreign construction enterprises that have entered the construction credit network in Hangzhou, and have corresponding qualifications;

2 enterprises in the administrative area of this Municipality within 1 year without major and above quality and safety accidents;

Eighth to participate in the city standardization excellent site selection site must meet the following conditions:

1 projects completed in the new round of selection cycle;

2 in line with the national capital construction procedures, the main market behavior norms of all parties to the project construction;

3. Has been included in the district, county (city) Construction Bureau and the municipal quality safety supervision station to create a standardized excellent site plan, in line with the relevant national, provincial and municipal construction safety technical standards, specifications and requirements, and the relevant provisions of safe production and civilized construction, and the management of safe production and civilized construction has reached an advanced level;

4. Actively promote the use of new materials, new technologies, safety protection facilities, construction machinery and equipment and green construction measures;

5. Establish grass-roots party organizations at the construction site, and carry out activities such as party building and joint construction with construction administrative departments, regulatory agencies or territorial communities;

6 for the construction safety production liability insurance (or liability insurance with the same nature as the safety liability insurance);

7. Actively implement other work assigned by construction administrative departments at all levels.

Chapter III Establishment of Declaration

Ninth to participate in the city standardization excellent site selection site by the general contractor of the project to declare, the construction permit information exists more than two (including two) contractors, should take a joint declaration.

Professional contracting enterprises that have completed Jian ‘an project account for more than 20% of the project quantity, and construction enterprises in residential quarters (including contiguous houses and public buildings) that account for more than 10% of the project Jian ‘an project quantity can declare as contractors, but the total number shall not exceed three.

Article 10 When applying for a project with excellent standardized site in the city, the enterprise shall include the creation plan in the annual management target of safety production before the start of construction, and formulate the implementation plan for the project with excellent standardized site. Fill in the creation schedule (Table 1) within 30 working days after the project starts, and report it to the supervision institution.

Article 11 The supervision institution shall, within 10 working days after accepting the enterprise’s creation schedule, make a preliminary investigation on the scale and conditions of the declared project, and register those that meet the selection requirements. The construction unit shall fill in the "Receipt Form of Excellent Site Election Card for Standardized Management of Construction Safety in Hangzhou" (see Annex 2), and go to the Municipal Construction Industry Association to receive the plaque of "Excellent Site Election Project for Standardized Management of Construction Safety in Hangzhou" after being confirmed by the seal of the supervision institution, and hang it at the gate of the construction site to accept social supervision. The plaque is made by the Municipal Construction Committee.

Article 12 From the second month after the start of construction and the end of the project completion acceptance, the enterprise shall fill in the Self-assessment Form for Municipal Standardization Excellent Site Inspection (Form for Construction and Supervision Enterprises) (Annex 3) every month, and take photos of different parts of each sub-category reflecting the safe and civilized construction according to the ten sub-categories of the Construction Safety Inspection Standard (JGJ59-2011), and upload them to the platform of Hangzhou Standard Chemical Industry Comprehensive Supervision System (hereinafter referred to as

Thirteenth enterprise application data and dynamic management data of supervision institutions must be uploaded to the system platform. After the selection is started, the supervision institution will review the application materials of excellent standardized construction sites uploaded by enterprises on the system platform, and summarize the projects that have been approved and submitted to the Municipal Construction Committee. The specific application materials on the system platform are as follows:

1. Application Form for Excellent Site of Hangzhou Construction Safety Production Standardization Management (Annex 4);

2. Report the three-stage inspection and evaluation form of the construction site (foundation, main body and decoration) (Annex 5);

3. Inspection record form of supervision institution (Annex 6);

4. Introduction of the reporting enterprise on the creation of excellent site for city standardization;

5. If there are contractors, provide the certification materials of contractors;

6. Records of project completion acceptance;

7. Other supporting materials that need to be provided;

8. Pictures and images of the project construction site.

Chapter IV Dynamic Management

Article 14 The supervisory institution shall, according to the establishment plan of the declared enterprise and on the basis of daily supervision and management, randomly check the basic stage, main construction stage and decoration stage at least twice each, and fill in the Inspection Record Form of Supervisory Institutions in time.

Fifteenth city standardized excellent site listing, delisting dynamic supervision and management system. In the process of construction, any of the following circumstances shall be delisted and its qualification for creation shall be cancelled:

1. General and above safety production accidents occur;

2 by the construction administrative department to make general administrative punishment;

3. Accidents of production safety responsibility such as overturning of hoisting machinery, collapse of foundation pit, collapse of formwork support system, fire, etc. occur, although no casualties are caused, but the social impact is bad;

4. Other events that have caused great negative social impact occur.

Sixteenth in the construction process, one of the following situations will be given a yellow card warning; In the construction period of the project, those who have been warned twice by yellow cards will be delisted and disqualified:

1. The use of construction machinery, equipment, products and processes prohibited by the state;

2. Having been given two simple administrative punishments by the administrative department of construction within one year;

3 due to arrears of wages of migrant workers, construction noise, dust pollution, etc., it is the responsibility to complain and report, resulting in adverse social effects.

4. The site management of the construction workers is not in place and is completely shut down by the competent construction department.

Article 17 The construction engineering safety supervision institution shall specify the telephone number of complaints, accept the complaints and reports of violations of laws and regulations in the construction site with excellent standardization, and verify them in time. Anyone who meets the requirements in Articles 15 and 16 of these Measures shall be given a yellow card warning or delisted; Delisting projects shall not be declared to be excellent construction sites of city standardization, and at the same time, differentiated management shall be implemented and supervision shall be strengthened.

Chapter V Selection Methods and Procedures

Article 18 The Municipal Construction Committee established the Hangzhou Excellent Site Selection Committee (hereinafter referred to as the jury) for standardized management of construction safety in construction projects. The jury has an office (located in the Engineering Department of the Municipal Construction Committee). The office of the jury is responsible for the daily work of the selection of excellent construction sites for standardization.

Nineteenth establish a system platform, form an electronic file for the management of safe and civilized construction of declared projects, and fairly and objectively display the dynamic management process of safe and civilized construction of declared projects.

Article 20 The project score is based on the percentage system, which consists of the process evaluation score of the supervision institution (accounting for 50 points) and the expert evaluation score (accounting for 50 points), in which the process evaluation score of the supervision institution is converted by the average score on site; The expert evaluation score is a comprehensive evaluation score of the establishment and management of the enterprise standard chemical industry, the monthly self-evaluation form of the enterprise and the photos of the construction site in the application materials.

If the sum of the two scores exceeds 80 points, they are eligible to participate in the voting session of the Municipal Standardization Excellent Site Jury.

Twenty-first the following circumstances can be based on the evaluation score of the project, and the project can be added or subtracted:

1. Extra points:

(1) those who actively organize and participate in the party building activities in the industry and win the commendation honor of the party building in the industry or hold the on-the-spot meeting of party building, according to the district (county), city, province and ministerial level, can add 1, 2, 3 and 5 points respectively;

(2) Organize the on-site meetings of quality, safety and civilized construction at district (county), city, province and ministerial level, and add 2, 4, 6 and 10 points respectively;

(3) District (county), city, province, the State Council construction administrative departments informed in recognition, respectively, add 1, 2, 3, 5 points.

If you add points to the same item, it will be high or low, and you will not repeat the points.

2. Subtraction:

(1) informed criticism, the administrative department in charge of construction in the district (county), city, province and the State Council, will be deducted 2 points, 4 points, 6 points and 10 points respectively. If the same item is deducted, it will be high or low, and it will not be repeated.

(2) If a summary administrative penalty is imposed, 2 points will be deducted each time;

(3) Failing to hang the plaque of "Excellent Site Participation Project of Hangzhou Construction Safety Production Standardization Management" as required, 1 point will be deducted each time.

Twenty-second comprehensive project score is determined, the Municipal Construction Committee organized a jury meeting. The members of the jury shall be composed of relevant offices of the Municipal Construction Committee, directly affiliated units and district and county (city) construction bureaus, and the members of the jury and evaluation experts shall not repeat.

According to the project evaluation, process evaluation and expert evaluation opinions, and combined with the evaluation, the members of the jury selected the winning project by secret ballot. Vote for the number of participating projects that reach more than two-thirds (including two-thirds) of the number of judges, and obtain excellent construction sites for city standardization. Voted to reach more than half of the number of judges (including half), less than two-thirds of the participating projects, won the honorary title of city praise project.

Twenty-third winning projects shall be publicized on Hangzhou Construction Online, and the publicity period shall be 7 working days, subject to social supervision. If there is no objection at the expiration of the publicity period, a document will be issued to announce the selection results.

Chapter VI Selection Discipline and Reward

Twenty-fourth reporting enterprises should adhere to the principle of seeking truth from facts, and the application materials should not be falsified. Violators will be disqualified from reporting and participating. When accepting the inspection, it is not allowed to stop work and wait for inspection, and it is not allowed to entertain and give gifts. Once found and verified, it will be criticized according to the seriousness of the case until the qualification for declaration and participation is cancelled.

Article 25 The inspectors, examiners and assessors should handle affairs impartially, strictly observe discipline, consciously resist unhealthy practices, give criticism and education, warn or revoke the qualifications of violators according to the seriousness of the case, and report to their units for handling.

Twenty-sixth to obtain excellent site standardization and praise the site, by the Municipal Construction Committee issued a document for the city.

Chapter VII Supplementary Provisions

Twenty-seventh management measures by the Municipal Construction Committee is responsible for the interpretation of.

Article 28 District and county (city) Construction Bureaus and municipal quality safety supervision stations may, in accordance with these measures, formulate measures for the implementation of the selection and management of excellent sites for standardized management of construction safety in construction projects of their own departments (units).

Twenty-ninth the management measures shall be implemented as of July 15, 2020. The original Notice on Printing and Distributing the Measures for the Administration of Standardized Model Construction Sites for Safe Production and Civilized Construction of Construction Projects in Hangzhou (Hangzhou Construction Engineering Development [2005] No.703) and the Notice on Further Strengthening the Administration of Standardized Model Construction Sites for Safe Production and Civilized Construction of Construction Projects in Hangzhou (Hangzhou Construction Engineering Development [2007] No.547) shall be automatically abolished after the implementation of these Measures.

Attachment: 1.(XXXX) Excellent Construction Site with Standardized Management of Construction Safety in Hangzhou Construction Project in 2008

2. Hangzhou construction project construction safety production standardization management excellent site election card to receive a single.

3. Hangzhou Standardized Excellent Site Inspection Self-evaluation Form (used by construction and supervision enterprises)

4. Hangzhou Construction Project Safety Production Standardization Management Excellent Site Declaration Form

5. "Three-stage" inspection and evaluation form (foundation, subject and decoration)

6. Inspection Record Form of Supervisory Body