What are cytokines?

Cytokines are a kind of multifunctional, low molecular weight and secretory protein, which can reach other parts of the body more easily through blood and lymph circulation, such as kidney, liver, bone marrow, spleen and lymph nodes. When the body is infected by pathogenic microorganisms, immune cells, epithelial cells at the infected site and vascular/lymphatic endothelial cells will produce a variety of cytokines, which will call immune cells to the infected site and jointly form a defense response to clear the infection.

Cytokines can be divided into two categories: one is pro-inflammatory cytokines, which can help activate many kinds of immune cells and promote the occurrence and development of inflammatory reactions. The second type is anti-inflammatory cytokines, which, as the name implies, can subside or inhibit inflammatory reaction and make the body return to steady state.

When infected by pathogenic microorganisms, various cytokines released by immune cells, epithelial cells, endothelial cells, etc. act on receptors on the surfaces of other cells to establish a network of cytokines and even various immune cells, and accurately and timely regulate the process and degree of anti-infection immune response. When the body uses cytokines and other immune effector molecules to remove pathogenic microorganisms, the inflammatory reaction subsides and the body returns to steady state.

For example, IL-6 can not only promote the expression of IL-1β and TNFα-α, but also help other lymphocytes to activate, or recruit more neutrophils and macrophages to accumulate in infected tissues. Cells (such as regulatory T cells, Treg) and cytokines (IL-10 and TGF-β) that can antagonize or inhibit inflammation play an important role in the regression period of inflammatory reaction.

The main types of cytokines include interleukin ,IL), interferon ,IFN), chemokine ,CK), tumor necroptosis factor ,TNF), transforming growth factor β (TGF-β) family and colony-stimulating factor ,CSF).

Why detect cytokines?

Cytokines are involved in immune and inflammatory reactions of the body, which are very sensitive inflammatory indicators. Dynamic monitoring of cytokine levels in the process of disease development can timely find the tendency of disease to get worse, treat it in time, avoid or reduce the risk of deterioration of the disease, achieve "no serious treatment" and improve the effective rate of clinical treatment.

At present, the joint detection of cytokines includes six, seven, twelve and fourteen items, including IL-1β, IL-2, IL-4, IL-6, IL-8, IL-10, IL-12, IL-17 and TNF-α.

Combined detection is helpful for clinical realization:

1.Auxiliary diagnosis of early infection, timely guidance of treatment, to avoid the deterioration of the disease; Evaluate the efficacy earlier and avoid overtreatment.

2. Identify the source of infection

Studies have shown that cytokines will increase and change in different degrees when infected by bacteria and viruses. When the relevant cytokines exceed the critical value, they can be used as the basis for identifying the source of infection.

3. Early warning of cytokine storm and timely treatment can improve the survival rate of critically ill patients.

Sepsis, severe infection, hemophagocytic syndrome, tumor immunotherapy, fever to be investigated, rare mutant virus infection or patients undergoing major surgery can all cause cytokine storms. Monitoring cytokines and timely treatment can improve the survival rate of critically ill patients.

4. Evaluate the inflammatory and immune status of the body (SIRS/CARS/MARS) and provide accurate treatment.

Severe patients may have three inflammatory/immune states: SIRS (Systemic Inflammatory Response Syndrome), CARS (Antagonistic Inflammatory Response Syndrome) and MARS (Mixed Antagonistic Response Syndrome). Monitoring the level of cytokines in critically ill patients is helpful to distinguish the immune/inflammatory state and provide accurate treatment.

5. Monitor the immune function of critically ill patients.

Severe patients generally have severe infection or inflammation. Under normal immune function, pro-inflammatory cytokines will increase significantly. If cytokines in severe patients do not increase or slightly increase, but CRP or white blood cells increase significantly, it indicates that patients’ immune function is inhibited.

6. Early warning of abortion and pre-eclampsia risk

Normal pregnancy requires the maternal immune system to recognize the fetal antigen from the father and produce immune tolerance. If the immune tolerance microenvironment is out of balance, it will lead to abortion. Therefore, the detection of cytokines can evaluate the risk of abortion of pregnant women and the clinical therapeutic effect of some infertile patients.

7. Guide the clinical application of hormones/anti-inflammatory drugs to avoid excessive dosage and lead to excessive immunosuppression.

Patients with strong inflammatory reaction need hormone therapy, but too high dose of hormone/anti-inflammatory drugs can easily lead to low immune function. Detection of cytokines can evaluate the immune function of the body, guide clinical dose adjustment, and reduce the risk of secondary infection caused by hormone/anti-inflammatory drugs.

8. Autoimmune disease condition/efficacy monitoring

The pathological injury mechanism of autoimmune diseases is inflammatory reaction, and cytokines play an important role in the pathological injury process of autoimmune diseases, such as IL-6, IL-8 and TNF-α in rheumatoid arthritis. By monitoring the changes of cytokines, the therapeutic effect and condition of autoimmune diseases can be evaluated.

9. Monitor the progress/prognosis and curative effect of inflammation caused by radiotherapy and chemotherapy/immunotherapy/postoperative.

After chemotherapy or immunotherapy, tumor patients will lead to an increase in the level of pro-inflammatory cytokines, leading to a strong inflammatory response. Detection of cytokine levels can evaluate the severity of inflammatory response caused by radiotherapy and chemotherapy or immunotherapy.

At present, the immunotherapy effect of PD-1 or CAR-T on tumors has been recognized by clinical experts and patients, but at the same time, there are serious clinical adverse reactions, among which the highest and most serious one is cytokine release syndrome (CRS). CRS is characterized by a large increase of multiple cytokines, with a single cytokine increasing by more than 250 times and two or more cytokines increasing by more than 75 times, which indicates the occurrence of CRS.

Excluding infection, if the level of Th1 cytokines (IL-2, IFN-γ, TNF-α) increases, it indicates that the tumor condition is getting better or the treatment scheme is effective. If the level of Th2 cytokines (IL-4, IL-6, IL-10) is increased, it indicates that the tumor is progressing or the treatment scheme is ineffective.

summarize

As a sensitive inflammatory index, the imbalance of cytokine expression and regulation is related to the occurrence and development of many diseases, which has a wide range of application values in clinical departments and is an ideal monitoring index for precision medical treatment and personalized treatment.

END

WenzhanglaiSource: Zhengzhou Huawo Medical Inspection Institute, reservation.Please contact us if there is any infringement or reprinting restriction, and we will contact you as soon as possible to delete it.　

Editor: Green is about to drip

Review: Chenchen

　　　　　　 CCTV News:The Sichuan Provincial Public Security Department recently announced a serious drug trafficking case supervised by the Ministry of Public Security. The case involved six gangs, and the police arrested 32 drug-related suspects for more than four months.

　　　　　　 In August this year, the police in Suining, Sichuan cracked a drug trafficking case with zero packages. The person involved confessed that the drugs were purchased from Gan and Cheng, and there were drugs waiting to be traded. The police followed the trail and found that Gan and Cheng, who had lived in Chuxiong, Yunnan for a long time, bought Magu and heroin from Yunnan and organized Sun and others to drive them to Suining, Sichuan, and then sold them to Liu and many others. After Liu bought Ma Gu, he exchanged ice poison with Qi Mou of Suining. The ice poison of Qi Mou came from Deng Mou and others, and the ice poison of Deng Mou and others came from Huang Mou and others in Chengdu. The whole case involved six gangs in Suining, Yibin and Chengdu, and the case was serious. The Suining Public Security Bureau set up a task force to collect the net under the unified command of the Anti-drug and Anti-drug Corps of the Sichuan Provincial Public Security Department.

　　　　　　 Police of the Anti-drug Detachment of Suining Public Security Bureau: "At that time, we felt that the time was ripe for closing the net. We started at the same time in Suining and Yibin, and all the drug traffickers in Yunnan were arrested with the cooperation of Yunnan police."

　　　　　　 Policeman: "What’s in the bottle?"

　　　　　　 Suspect: "Drugs."

　　　　　　 Policeman: "What drugs?"

　　　　　　 Suspect: "Ma Gu."

　　　　　　 The police have arrested 32 suspects for transporting and selling drugs, seized 1,521 grams of crystal meth, 3,324 grams of magu, 1,686 grams of heroin, seized 220,000 yuan of drug money, 3 pistols and 11 bullets.

　　　　　　 Police of the Anti-drug Detachment of Suining Public Security Bureau: "We were all shocked by a cold sweat at that time, because two bullets were found at the bedside of the suspect Long, and a gun was loaded in his bed, and there were four bullets in the gun."

　　　　　　 Liu Hongen, deputy head of the anti-drug detachment of Suining Public Security Bureau: "This case spans Yunnan, Sichuan and Chongqing. There are many people involved and there are many kinds of drugs involved. The case has seized heroin, ice and Ma Gu, both involved in drugs and guns. Some suspects protect drugs with guns and carry guns."

　　　　　　 According to the police, this serious drug trafficking case is a typical case of long-distance inter-provincial transportation and drug trafficking, involving two provinces and one city; Criminal suspects still have family-style drug trafficking, and they also have a strong anti-investigation consciousness in the way of transporting drugs and avoiding arrest.

　　　　　　 Police of Anti-drug and Anti-drug Brigade of Anju District Branch of Suining Public Security Bureau: "Generally, they rent two cars. The first car will clear the way, just explore the road ahead, and see if there are any police checkpoints on the expressway and the bayonet along the way. The car behind will transport drugs. Time is usually on weekends or major holidays, so he thinks that our police are resting or when the police are off work, in order to avoid inspection. "

　　　　　　 The police also found that among the criminal gangs, many people belong to relatives, and some criminal suspects never live in a fixed place in order to avoid arrest.

　　　　　　 Police of Anti-drug and Anti-drug Brigade of Anju Branch of Suining Public Security Bureau: "The suspect Zhang Moumou never lives in a fixed place. He usually lives in a car or in a bathing center where he can stay."

　　　　　　 At present, 23 of the 32 suspects have been arrested by the procuratorate, and the case is under further investigation.

　　"Human beings are created by labor, and society is created by labor";

　　"People create history and labor creates the future";

　　"All happiness in the world needs to be created by hard work";

　　"The model worker is the elite of the nation, the model of the people and the hero of the Republic";

　　"Labor is the most glorious, the noblest, the greatest and the most beautiful";

　　"Model worker spirit, labor spirit and craftsman spirit are vivid manifestations of the national spirit with patriotism as the core and the spirit of the times with reform and innovation as the core, and are powerful spiritual driving forces that inspire the whole party and the people of all ethnic groups throughout the country to March forward bravely";

　　… … … …

　　Since the 18th National Congress of the Communist Party of China, the General Secretary of the Supreme Leader has deeply praised the labor creation, eulogized the spirit of model workers, laborers and artisans, led the whole society to carry forward the glorious labor, valuable skills and great fashion of the times, condensed the powerful force of hundreds of millions of working people to forge ahead in unity, created the great achievements of Socialism with Chinese characteristics in the new era, and pushed China onto a new journey of building a socialist modern country in an all-round way.

　　Sweat irrigates the harvest, and work hard to move forward. The people of China, who have stepped into a new journey and have a stronger sense of historical consciousness and initiative, are firmly relying on labor creation to promote Chinese modernization and strive to create a better future with their own hands.

　　"The whole society should respect model workers and carry forward their spirit."

　　"When I saw the letter, I remembered the scene of communicating with you in the workshop ten years ago."

　　On September 1st this year, General Secretary of the Supreme Leader wrote back to the workers of "Li Zhiqiang Class" of China Hangfa Liming Engine Assembly Factory, which made Li Zhiqiang, a 59-year-old national model worker and national technical expert, feel surge of emotion. "The general secretary told us to carry forward the spirit of model workers and artisans. We have always been deeply engraved in our hearts and become a source of strength for us to overcome difficulties and forge ahead."

　　Talk and entrust, inspiring people. In the past ten years, everyone in "Li Zhiqiang Class" has worked hard, achieving 126 technological innovations, developing 312 tooling tools, applying for more than 50 invention patents, and solving 52 technical problems in scientific research and assembly.

　　Model workers are outstanding representatives of the working people and the most beautiful workers. General Secretary of the Supreme Leader always holds the most sincere respect for the model workers.

　　"Today, we see the bright stars, and the representatives of different historical periods are all here … … Everything is vivid, and we are all experienced and witnesses. Seeing everyone, I am in awe of the model workers, and the feelings of respecting knowledge and respecting labor are born. "

　　On April 28th, 2013, in an ordinary conference room of the All-China Federation of Trade Unions, the General Secretary of the Supreme Leader had a heart-to-heart talk with 65 representatives of model workers from different industries and different historical periods all over the country to celebrate May Day. Sincere words spread all over China from a small conference room.

　　After listening to the speech of Liang Jun, the first female tractor driver in New China, the Supreme Leader General Secretary said, "Your deeds are known to people of our age. The first female tractor driver in China, you are amazing. "

　　"Great" and simple three words reveal the supreme leader’s general secretary’s respect for model workers.

　　Holding a model worker’s meeting and wearing big red flowers are good memories of generations of new China for "glorious labor".

　　"Model workers and advanced workers are models for adhering to the road of China, carrying forward the spirit of China and rallying China’s strength. With a high sense of ownership, outstanding labor creation and selfless hard work and dedication, they have set an example for people of all nationalities in the country to learn." On April 28, 2015, at the celebration of the May 1 International Labor Day and the commendation of the National Conference of Model Workers and Advanced Workers, the words of the Supreme Leader General Secretary became a lofty tribute to the workers in the new era.

　　In all historical periods when our Party unites and leads the people in revolution, construction and reform, the model workers have always been a shining group: from Wang Jinxi, an "iron man" and Deng Jiaxian, a "two bombs" in the socialist construction period, to Deng Jianjun, a "knowledge worker" and Wu Dengyun, a "sage in white" in the new historical period of reform and opening up, to Huang Dafa and a "deep-sea fitter" who dug a "life canal" on the cliff in the new era. … Generation after generation of model workers write a touching chapter of "changing the world" with the passion of creation, innovation and entrepreneurship. Their glory is engraved in the history of the Republic.

　　Stepping into the new era, from major projects such as the Hong Kong-Zhuhai-Macao Bridge, Baihetan Hydropower Station and Hualong No.1 nuclear power unit, to scientific and technological miracles such as "Chang ‘e" lunar exploration, "Dragon" deep diving, Beidou networking, and to crucial battles such as pollution prevention and accurate poverty alleviation, all fronts of economic and social development have left the footprints and hard work of model workers.

　　"Bridge crane operation is like air ‘ Thread the needle ’ ！” Zhoushan Port in Ningbo, Zhejiang Province, at an altitude of more than 40 meters, Zhu Shijie, a national model worker, led the team to complete container loading and unloading quickly and accurately.

　　On March 29th, 2020, General Secretary of the Supreme Leader visited here. "The general secretary told me to play a good role as a model worker and bring out more model workers." This entrustment made Zhu Shijie full of energy.

　　In the past three years, the "Zhu Shijie Bridge Crane Operation Method" was upgraded to version 4.0, and the "Zhu Shijie Innovation Studio" trained more than 3,000 bridge crane drivers, and a group of highly skilled talents led by provincial model workers came out of the team.

　　How fine is 1 micron? 1/60th of a hair!

　　Chen Liang, a national model worker and a senior technician of Wuxi Weiyan Co., Ltd., is good at controlling the mold accuracy within 1 micron. "If you are a little more careful, you will be a little closer to the accuracy of 1 micron!" In order to better cope with every challenge, Chen Liang set such a working principle for himself.

　　… … … …

　　The new era is the era of strugglers, and the model workers are the most beautiful strugglers.

　　General Secretary of the Supreme Leader profoundly explained the spirit of model workers: "In the long-term practice, we have cultivated and formed the spirit of model workers who love their jobs, strive for first-class, struggle hard, be brave in innovation, be indifferent to fame and fortune, and be willing to contribute."

　　"Love one’s job and strive for first-class" embodies the true nature and pursuit of model workers; "Hard work and innovation" embodies the style and quality of model workers; "Indifferent to fame and fortune, willing to contribute" embodies the realm and cultivation of model workers. Model worker spirit inherits and develops the concept of labor in Chinese excellent traditional culture, which is a vivid embodiment of Marxist concept of labor.

　　Great times call for great spirit, and lofty undertakings need to be guided by examples. As an important part of advanced socialist culture, model worker spirit vividly interprets socialist core values, enriches the connotation of national spirit and spirit of the times, and is our extremely valuable spiritual wealth.

　　Respecting model workers and carrying forward the spirit of model workers, General Secretary Nianzi is here — —

　　"Vigorously carry forward the spirit of model workers, give full play to the role of the working class as masters, safeguard the legitimate rights and interests of workers and staff, and actively build harmonious labor relations";

　　"The whole society should respect model workers, carry forward the spirit of model workers, and make honest and diligent work a common practice";

　　"People of all ethnic groups in China should learn from the model workers, take the model workers as an example, give full play to the spirit of fighting against the clock and join in the grand cause of realizing the great rejuvenation of the Chinese nation";

　　… … … …

　　Under the call of the Supreme Leader General Secretary, all parts of the country praised and paid tribute to the advanced model workers with lofty courtesy. In the past five years, the All-China Federation of Trade Unions has commended 926 May Day labor awards, 4,026 May Day labor medals and 4,119 workers’ pioneers nationwide, which has encouraged trade unions at all levels to choose trees to publicize model workers and sing the songs of workers in the new era.

　　These grand commendations are enthusiastic praise for model workers, but also vigorously carry forward the spirit of model workers, and convey the deep love of the Supreme Leader General Secretary and the CPC Central Committee for model workers and advanced workers.

　　Socialism is done, and the new era is fought. Nowadays, the whole society advocates model workers, studies model workers, strives to be model workers and cares for model workers, and model workers are increasingly becoming one of the most shining groups in the whole society; "Model Worker Innovation Studio" is spread all over the country, demonstrating and leading all walks of life to promote high-quality development with hard work, honest work and creative work.

　　"As long as you work hard and diligently, you can do extraordinary things in ordinary posts."

　　Digging, pit construction, cofferdam reclamation, water lifting and watering … … In April this year, General Secretary of the Supreme Leader came to the tree planting site in Dongba Central Park, Chaoyang District, Beijing in the rain. While working, he taught the children how to plant trees and told them to love labor from an early age and achieve all-round development in morality, intelligence, physique and beauty.

　　Since the 18th National Congress of the Communist Party of China, every spring, the General Secretary of the Supreme Leader has participated in voluntary tree planting activities and worked with the masses.

　　"When I got off the bus, I took a shovel on my shoulder and walked towards us laughing and laughing." "At first glance, the general secretary is the old style of doing farm work." The people who planted trees together felt warm and cordial.

　　An old photo is also warm. It was in 1989, when the supreme leader comrade, then secretary of the Ningde prefectural party committee, led the cadres of the local organs to participate in voluntary labor, with a smile on his face and a hoe on his shoulder, striding on the ridge of the field.

　　Years are long, and the true colors do not change.

　　Along the way, the General Secretary of the Supreme Leader has a consistent understanding of labor and a firm feeling for the working people.

　　"Our roots are rooted among the working people." From ploughing the grass roots to piloting China, the General Secretary of the Supreme Leader has always maintained the true nature of workers, and always insisted on "standing on the side of the overwhelming majority of working people", standing together with the working people, wanting to be together and working together.

　　Babusha Forest Farm in Gulang County, Gansu Province, picked up a ditching plough and participated in the sand control work;

　　At the mouth of the Yellow River, I bent over to pick the pods, twisted them one by one, put a soybean in my mouth and chewed it carefully: "The beans grow well";

　　On the land of the Central Plains, I held up the ears of wheat to watch the grouting and kindly said to my fellow villagers, "We are all from crops";

　　Beijing Caochang Hutong, surrounded by jiaozi with its neighbors;

　　Xiangxi grapefruit forest, skillfully helping villagers pick grapefruit;

　　… … … …

　　The people’s leaders who came out of the working people know that "people’s livelihood is diligent, but diligence is not scarce" and have repeatedly encouraged everyone that "as long as they work hard and diligently, they can also achieve extraordinary results in ordinary posts" and "no matter what kind of work they are engaged in, they must do, love and drill".

　　At the opening ceremony of the 2022 Beijing Winter Olympics, a five-star red flag was passed in the hands of more than 100 ordinary Chinese, including Liu Kuo, a representative of the "courier brother".

　　On the eve of the Spring Festival in 2019, Liu Kuo and his colleagues met the Supreme Leader General Secretary who came to visit them at the Stone Hutong Express Station in Qianmen, Beijing.

　　I heard that everyone can’t go home until 30 years old. The general secretary said that "courier brother" works very hard. He gets up early and gets greedy in the dark, rain or shine. The busier the holidays are, like hardworking bees, he is the hardest worker and brings convenience to everyone’s life.

　　"I have always kept in mind the words of the general secretary and tried to be a hardworking little bee." Recalling the kind words of the General Secretary, Liu Kuo still felt extremely warm in his heart.

　　The background color of labor is cast into the true colors of the people. The General Secretary of the Supreme Leader stressed: "We must firmly establish the concept of the most glorious, noble, greatest and most beautiful labor, so that all the people can further glow their enthusiasm for labor, release their creative potential and create a better life through labor."

　　Promoting the worship of labor has become a common practice in the whole society, and it is necessary to benefit workers, make them feel glorious and get social respect.

　　The working class and the broad masses of working people are anxious about their difficulties, safety and warmth, and the General Secretary of the Supreme Leader has always been in his heart. Hebei Fuping Zhuangjiayuan, hand in hand with the people in difficulty, calculated the poverty alleviation account and increased the account together, and said, "We must try our best to let the villagers live a good life as soon as possible"; On the Beijing subway construction site, a pink schoolbag was given to the daughter of Fan Yong, a steel worker, emphasizing "to arrange their life during the festival" … …

　　Since the 18th National Congress of the Communist Party of China, the General Secretary of the Supreme Leader has come to the grassroots front-line workers again and again, asking about the changes in temperature, listening to hardships, encouraging efforts, advocating labor and respecting workers.

　　From in-depth investigation at the grass-roots level to presiding over relevant meetings, General Secretary of the Supreme Leader has always been very concerned about the protection of workers’ rights and interests — —

　　"Migrant workers are a new type of labor force that has emerged since the reform and opening up, and they are an important force in building the country. The whole society must care about and care for migrant workers";

　　"Pay attention to front-line workers, migrant workers, workers with difficulties and other groups, improve the system, remove obstacles that hinder workers from participating in development and sharing development achievements, and strive to enable workers to achieve decent work and all-round development";

　　"It is necessary to improve the social security system of multi-channel flexible employment and safeguard the legitimate rights and interests of truck drivers, courier brothers and take-away distributors";

　　… … … …

　　Rely on the people, always for the people. From the standpoint of the people, General Secretary of the Supreme Leader profoundly explained the scientific connotation of labor spirit: "advocating labor, loving labor, hard work and honest labor".

　　Looking back at the brilliant achievements of the new era, we have completed the historical task of getting rid of poverty and building a well-off society in an all-round way, and achieved the goal of the first century. Every leap forward in history embodies the hard work and struggle of hundreds of millions of working people.

　　Last October, during his first inspection tour to Beijing after the 20th National Congress of the Communist Party of China, General Secretary of the Supreme Leader came to Hongqi Canal in Linzhou, Anyang, Henan.

　　From 1960 to 1969, 100,000 sons and daughters of Linxian County worked hard to build a 1,500-kilometer-long natural canal on Taihang Mountain, and built a spiritual monument spanning time and space.

　　"Socialism is spelled out, done and exchanged for life, not only in the past, but also in the new era." General Secretary of the Supreme Leader said earnestly.

　　The core connotation of labor is hard work and struggle. General Secretary of the Supreme Leader pointed out: "Labor is the fundamental force to promote the progress of human society … … We say ‘ Empty talk about making mistakes in the country, and doing things to revitalize the country ’ To do practical work, we must first work on the ground. "

　　"Labor has created the Chinese nation, created a glorious history of the Chinese nation, and will certainly create a bright future for the Chinese nation."

　　Looking at the land of China, in the fields where rice waves roll, in the factories where steel flowers splash, on the road of smooth logistics, in the quiet and tidy scientific research institute … … The broad masses of working people keep in mind the entrustment, write the songs of workers in the new era in their respective posts, create with great labor, and push the wheel of the times forward.

　　"Cultivate more high-quality technical and technical talents, skilled craftsmen and great country craftsmen"

　　"Great country craftsmen, the country needs people like you."

　　On June 29, 2021, the "July 1 Medal" was awarded at the Great Hall of the People in Beijing. The words of the Supreme Leader General Secretary made the "good welder" Ai Aiguo remember in his heart.

　　Working for more than 50 years, relying on a welding torch, Ai Aiguo constantly pursues Excellence and climbs the technical peak. "Being a worker means being a good worker", which is Ai’s patriotic professional creed. He said that a really good welder should study hard and think of ways to become a master of welding technology from a master of welding.

　　The quality of workers is very important to the development of a country and a nation. In today’s world, the competition of comprehensive national strength is, in the final analysis, the competition of talents and the quality of laborers.

　　"China has the institutional advantages of socialist market economy, the demand advantages of ultra-large-scale market, the supply advantages of complete industrial system, and the talent advantages of a large number of high-quality workers and entrepreneurs." In August this year, the Supreme Leader of president pointed out in his speech to the closing ceremony of the Johannesburg BRICS Business Forum.

　　Chinese modernization is a modernization with a huge population, and the high-quality development of population supports Chinese modernization.

　　Since the 18th National Congress of the Communist Party of China, the General Secretary of the Supreme Leader has always attached great importance to building a high-quality workforce, emphasizing that "contemporary workers should not only have strength, but also have wisdom and technology, be able to invent and innovate, and play the main theme of the times with practical actions", profoundly explaining the scientific connotation of the craftsman spirit: "persistent concentration, Excellence, meticulousness and pursuit of Excellence", and calling on the whole society to carry forward the craftsman spirit.

　　On April 27, 2022, the first great country craftsman innovation exchange conference was grandly opened. This is a grand event to pay tribute to model workers, exchange innovative achievements and improve the skills and quality of employees.

　　General Secretary of the Supreme Leader sent a congratulatory letter to the Congress, stressing that "the skilled workers are an important force supporting China’s manufacturing and China’s creation", and the working class and the broad masses of working people in China should "study hard, study hard, be brave in innovation and be the first, and constantly improve their technical skills".

　　"It is necessary to carry forward the craftsmanship spirit of Excellence in the whole society and inspire the vast number of young people to take the road of becoming talented and serving the country with skills";

　　"To create a grand industrial worker team with ideals and beliefs, knowledge of technology and innovation, and the courage to take responsibility and dedication";

　　"Enhance the adaptability of vocational education, speed up the construction of a modern vocational education system, and train more high-quality technical and technical talents, skilled craftsmen and great country craftsmen";

　　"Carry forward the spirit of model workers and artisans, and strive to conquer more key core technologies";

　　… … … …

　　Important speeches and instructions again and again are full of the deep concern of the Supreme Leader General Secretary for the skilled workers; When going to the local area for investigation and research, the general secretary often walks into the workshop team to visit the working people, ask about the production and living conditions, and point out the direction of development and progress.

　　In April this year, General Secretary of the Supreme Leader came to Guangzhou Automobile Research Institute during his inspection tour in Guangdong, and had cordial exchanges with representatives from all walks of life. Among them, there are senior engineers who participated in the development of Beidou chip, scientific and technical personnel who are committed to transporting solar power from Xizang to Guangdong-Hong Kong-Macao Greater Bay Area, and a great craftsman who has participated in welding projects such as new aircraft carriers & HELIP; …

　　Everyone spoke enthusiastically, and the General Secretary of the Supreme Leader listened attentively. The general secretary said earnestly: "The economy should develop continuously, and there should be no ups and downs. What is very important here is science and technology, education and talents. "

　　Big times, big stage. The road for industrial and technical workers to become talented and serve the country with skills is getting wider and wider.

　　"What is the sequence of your title?" When General Secretary of the Supreme Leader participated in the discussion of the Party’s 20th Guangxi delegation, he asked Zheng Zhiming, who was sitting opposite and dressed in workshop uniforms.

　　Master Zheng reported to the General Secretary: "Our country has issued a policy of breaking the ceiling. I have just been rated as a special technician and a senior engineer. The party’s policy has given our workers who graduated from vocational high schools a good way out. This was never thought of in the past. "

　　As a locksmith, Zheng Zhiming has worked in the front line for more than 20 years, and has developed exquisite skills in the "dialogue" with steel, and the machining accuracy of parts can be controlled at 0.002 mm.

　　These years, when Zheng Zhiming grew from a locksmith apprentice to a craftsman of a big country, it was also the time when China developed into a manufacturing power and accelerated towards a manufacturing power, and a large number of skilled workers became the trendsetter of the times.

　　Deng Jianjun, delegates to 20th National Congress of the Communist Party of China (CPC), has grown from a secondary school student to an expert engineer and a national skill master in the field of textile machinery in the world, and is known as the "leader of knowledge-based industrial workers" in China.

　　Zhou Yingfeng, a representative of the National People’s Congress, started as an ordinary CNC lathe worker and grew into a senior CNC lathe technician and a national technical expert with excellent technical strength.

　　… … … …

　　Countless industrial workers have dreams in their hearts, strength under their feet, and responsibility on their shoulders in the vast tide of the times, carry forward the spirit of artisans, be strugglers in the new era, and achieve wonderful life.

　　Up to now, there are more than 200 million skilled workers in China, accounting for 26% of the total employed population; There are more than 60 million highly skilled personnel, accounting for 30% of skilled workers, and they have become the backbone of China manufacturing and China creation.

　　"We step by step over the years, who are really building a modern and powerful building in Socialism with Chinese characteristics, they are all worthy of our respect. And we have to think and study how to cultivate them and play their role. This is important. " The words of hit the floor, General Secretary of the Supreme Leader, have warmed the hearts of industrial workers.

　　We workers have strength! History has proved that the working class in China has always had a glorious tradition of being in the forefront and shouldering heavy burdens bravely. The working class and the broad masses of working people have always been the fundamental forces to promote China’s economic and social development and safeguard social stability and unity.

　　"I hope that the broad masses of working people will vigorously carry forward the spirit of model workers, labor spirit and craftsman spirit, work honestly and diligently, be determined to innovate and dare to be the first, rely on labor creation to solidly promote Chinese modernization, and give full play to the role of the main force in the new journey of building a strong country and national rejuvenation." On the occasion of the May 1 International Labor Day this year, the Supreme Leader General Secretary extended festive congratulations and sincere condolences to the broad masses of working people throughout the country.

　　Labor creates happiness, and hard work makes great achievements. On the new journey, hundreds of millions of working people will bear in mind the entrustment of the General Secretary, vigorously carry forward the spirit of model workers, labor spirit and artisans, further glow their enthusiasm for labor and release their creative potential, which will surely unite the majestic power of building a strong country and national rejuvenation.

Special feature of 1905 film network The documentary film directed by Ren Jie was shown in the national cinema on December 3, 2021. The film truly recorded the deeds of the first secretary of poverty alleviation in villages all over the country, such as engaging in industry, promoting education, resisting typhoons and ensuring a bumper harvest, and told their vivid experiences of doing practical things for the people.

The "first secretary" refers to the first secretary in the village, who is also the closest person to the people in the fields and countryside. This "first" contains courage, responsibility, responsibility and mission. "We are the First Secretary" tells the touching stories of more than a dozen first secretaries in villages. Since the film was released, word-of-mouth performance has been good, with Cat’s Eye score of 9.4 and Taobao Film score of 9.2. This issue of "Today’s Film Review" invited Ren Jie, the director of this film, to talk about this film with you.

During the preparation of the film, there were more than 1,000 alternate secretaries with touching stories. In the end, Ren Jie selected more than 10 of them to shoot. Some of them led villagers to engage in industry, some set up kindergartens to promote education, some responded to natural disasters such as typhoons, some took care of crops to ensure a bumper harvest, some moved to other places to help the poor, and some even sacrificed their jobs for poverty alleviation … … What considerations did the creator make when choosing the secretary for shooting? Ren Jie mentioned: "We take into account the characteristics of gender and different cultural regions from different regions and time dimensions, and try our best to make the group of the first secretary fuller, so that the written reports seen by ordinary people from the news can be vividly changed back to flesh-and-blood figures, so we still choose in a wider range."

The film begins with the story of Wang Qingluo, a post-80s secretary, who chose to raise sheep to help the poor and lead everyone out of poverty. This angle is chosen as the opening, because Wangqing is the representative of industrial poverty alleviation, and industry is a key to fundamentally solve poverty. This angle is also friendly to the audience and easy to understand the concept conveyed by the film.

Ren Jie believes: "When we went to Tibet, the biggest problem of getting rid of poverty in our village was the industrial problem. In this home, industry is the key to complete the task of getting rid of poverty and fundamentally solve the poverty problem. Because at the time of filming, they were raised by retail investors and it was difficult to form an industry, so the secretary persuaded everyone to turn individual behavior into collective behavior, tide over the difficulties together, and build a new cooperative mechanism together. "

In the film, the story of Hu Xiaoming, the former first secretary of Bozuo Village in Butuo County, Sichuan Province, is impressive. After the secretary’s term of office, out of a sense of responsibility, he resolutely chose to return to his poverty-stricken Daliangshan village to help Secretary Luo Hong. He knows the local situation and has very sincere feelings for the local people. It is also because of him that the first kindergarten has been established in the local area. In addition, he also built a chicken farm and gave eggs to the children. When the children peeled eggshells and ate eggs in front of the camera and naturally smiled on their faces, the audience in front of the screen could feel the greatness of this poverty alleviation cause.

In fact, when interviewing Secretary Hu Xiaoming, the process was not smooth. Hu Xiaoming is willing to show his work, but he is somewhat resistant to showing his inner feelings in front of the camera. His mother was ill in bed and didn’t even recognize him. It is reasonable to say that he should take care of his mother before his deathbed, but he chose to stay here because of his responsibility to Daliangshan. Although he didn’t mention his feelings, the camera also captured his tender side.

Ren Jie said: "I know why these secretaries don’t want us to shoot this. First, they don’t want to cut open the soft side of their hearts. Second, they feel guilty about their families. Third, most importantly, they don’t have the heart of fame and fortune. But for me, it is possible to tell this story well. I need these things. I hope that the audience will not know the data and reports of the first secretary, nor the news communication in the traditional sense. I hope that it is their emotions and flesh-and-blood youthful strength and life. How did they spend these years in the most difficult moments in China? "

In February, 2021, we achieved a comprehensive victory in tackling poverty, and the lens of the film also shifted from tackling poverty to rural revitalization, which is also the next task mentioned by several first secretaries. After watching the film, An Mingtai, secretary of the Youth League Committee of the School of Drama and Film of Communication University of China and the first secretary of Cha ‘ersen Gacha in Horqin Right Front Banner of Xing ‘an League, said: "It really amazes me to have such a screen work to show to the audience. Poverty alleviation is only the first stage. How to make them develop better in the process of rural revitalization is what I need to consider, and this is also the biggest inspiration that the film has given me."

Su De Bi Lige, First Secretary of Wulan Halaga Sumuxin Guolegacha; Han Geng, First Secretary of Shanxi Yangpo Village; Qin Qian, First Secretary of Henan Sunzhuang Village; He Zhengzheng, First Secretary of Yangchun Xinpo Village; Guan Yanping, First Secretary of Zhuhai Basket Doctor; Ranbo, First Secretary of Liuzhou Anning Village; Wen Weihong, Feng Yongcheng, Wang Xinfa, Huang Wenxiu, Wang Qiuting, Yang Zhengqing, Zeng Hongmei and Zeng Yuxiang. … Behind these names are the feelings of not being afraid of difficulties, being the highest in the mountains and the selfless dedication to the people.

"We are the First Secretary" truly records the story that the first secretaries live a happy life for the people and practice construction of the village in an emotional way. What this film conveys is the spirit of courage, responsibility and dedication. These people’s public servants who irrigated the flowers of hope with faith and belief wrote their initial heart and dedication on the land of the countryside, which deserves to be remembered by the people forever.

Director’s Observation of Today’s Film Review

What impressed me most in the documentary film was Hu Shuji, Liangshan Yi Autonomous Prefecture, Sichuan. I know that place, where there are Xichang and Erhai Lake. But there are more mountains there. As the director said, although the countryside in Tibet is extremely cold, villages can still be seen. And the hinterland of Daliangshan, where slavery was finally eliminated in China, contains many hidden things. After the first term of office, Secretary Hu resolutely went back, hoping that what he had done would change there, help the children there and pay tribute to all the first secretaries in the front line. (Director of Luo Chuhao’s Today’s Film Review)

　　On November 30th, local time, the Federal Reserve released the National Economic Situation Survey Report (also known as the "Beige Book"), which showed that rising interest rates and high inflation continued to put pressure on economic activities, and the growth rate of the US economy slowed down. Federal Reserve Chairman Powell said on the same day that the Fed will continue to raise interest rates, but it may start to narrow the rate hike from December. The signal that the Fed will slow down the rate hike has boosted market confidence to some extent. However, under the current background of high inflation and rising interest rates, the US economic growth prospects are still not optimistic.

　　The negative impact of high interest rates and high inflation continues.

　　The report shows that rising interest rates and high inflation continue to put pressure on economic activities, and economic activities in the United States are basically flat or slightly rising, which is not as good as the moderate growth during the last "Beige Book". Among them, the economies of new york, Kansas City and other jurisdictions declined slightly, and only five jurisdictions experienced slight or moderate economic growth.

　　In the same period, the number of employed people in most jurisdictions increased moderately, but the demand for labor weakened as a whole. Although the labor market is still tense, it is easier for enterprises to recruit and retain existing employees. Science and technology, finance, real estate and other industries are decentralizing layoffs, and some enterprises are reluctant to lay off employees because of recruitment difficulties. On the average, wages have increased at a moderate rate, and the wage pressure in a few jurisdictions has eased. Looking ahead, employment growth tends to be stable or slow down.

　　In terms of prices, consumer prices in most jurisdictions rose moderately or strongly, but the overall increase slowed down, reflecting the double weakening effect brought about by the improvement of supply chain and weakening demand. Retail prices are facing downward pressure, but food prices in some areas have further increased or remained high. Inflation is expected to remain at the current level or rise moderately.

　　According to the contents of this "Beige Book", the rise in interest rates has caused different degrees of negative impact on consumer spending, manufacturing activities, real estate and construction, financial lending, commercial mergers and acquisitions and other fields. The report also shows that concerns about the economic recession are affecting corporate decision-making and consumer behavior in some jurisdictions.

　　The Federal Reserve publishes the "Beige Book" eight times a year, and conducts a thorough analysis of the economic situation in the United States through regional reserve banks. This report is an important reference for the regular meeting of the Federal Reserve’s monetary policy.

　　Or will start to slow down the pace of interest rate hikes.

　　While acknowledging that rising interest rates have brought "side effects" to the economy, the Federal Reserve has also released a signal that it will slow down interest rate hikes. Speaking at the Brookings Institution on November 30th, Federal Reserve Chairman Powell said that the Federal Reserve will continue to raise the federal funds rate, but it may reduce the rate increase from December.

　　Powell said that the Fed "still has a long way to go" from the goal of restoring price stability. Policy measures such as raising interest rates and reducing bonds usually take some time to play a role in the entire economic system. In the future, the Fed will continue to maintain its restrictive monetary policy stance until substantial progress is made in reducing inflation.

　　He said that when the interest rate is close to "the restrictive level enough to reduce inflation", it is "reasonable" for the Fed to slow down the rate hike, and "it may be the time to slow down the rate hike at the December meeting at the earliest". However, at present, the Fed has not made significant progress in reducing inflation.

　　After Powell’s speech, the US stock market soared. As of the close of the day, the Standard & Poor’s 500-stock index rose 3.09%, ending three consecutive days of decline and closing at 4080.11 points; Dow Jones Industrial Average rose 2.18% to 34,589.77 points; The Nasdaq Composite Index rose 4.41% to close at 11,468.00. Affected by the performance of the US stock market and other good news, major stock markets in Asia also generally rose on December 1.

　　In addition, the yield of US Treasury bonds has fallen sharply. According to the Associated Press, the yield of 10-year US Treasury bonds dropped to 3.65% from 3.75% at the close of the previous day. The yield of two-year treasury bonds, which tends to track the market’s expectations of the Fed’s future actions, fell from 4.48% to 4.34%.

　　Greg Basuke, CEO of AXA Investment Company, said that Powell’s statement is the "certainty" that investors are looking for in the Fed’s interest rate hike expectations. It is expected that the Fed will probably raise interest rates by 50 basis points in December.

　　Since March this year, the Federal Reserve has raised interest rates six times in a row, including 75 basis points in the last four times. According to a tracking data of the Chicago Mercantile Exchange, it is estimated that the possibility that the Fed will shrink the rate hike to 50 basis points by then is about 77%.

　　The uncertainty of economic prospects is rising.

　　Although the signal that the interest rate hike will slow down has boosted market confidence to some extent, in the context of high inflation and rising interest rates, the prospects for US economic growth are still uncertain. According to the Beige Book, looking forward to the future, all jurisdictions believe that the uncertainty of the economic outlook has increased, and the pessimism about the economic outlook has also intensified.

　　The latest economic data is mixed. According to the revised data released by the US Department of Commerce on November 30th, the gross domestic product (GDP) of the United States increased by 2.9% at an annual rate in the third quarter of this year, 0.3 percentage points higher than the initial data released at the end of October. However, personal consumption expenditure, which accounts for about 70% of the US economy, increased by 1.7%, still less than the 2% increase in the second quarter. In addition, residential investment contracted for the sixth consecutive quarter, the longest duration since 2006.

　　Data from the US Department of Commerce also showed that the US merchandise trade deficit surged by 7.7% to $99 billion in October due to the decline in exports. Reuters said that the sharp expansion of the trade deficit means that the trade performance may drag down the GDP data in the fourth quarter.

　　The inflation outlook is still facing uncertainty. According to the latest data from the US Department of Labor, the year-on-year increase of the consumer price index (CPI) in October was the smallest since January this year, and the year-on-year increase of the producer price index (PPI) in October has also continued to narrow since June. In this regard, Powell said that short-term data may be deceptive. At present, inflation is still at a high level, and more evidence is needed to prove that inflation is actually declining.

　　In addition, the tension in the labor market has not been significantly improved. The increase in economic uncertainty and the recent layoffs of large companies have made Americans even more reluctant to leave their current jobs. The turnover rate, which is regarded as an indicator of confidence in the job market, has dropped from the previous 2.7% to 2.6%. In November, the recruitment of American companies fell to the slowest pace in the past two years. The increase in the number of job vacancies also shows that the shortage of workers persists, which economists say is one of the reasons for the slowdown in employment growth.

　　Isfar Munir, an economist at Citigroup in new york, said that the data show that the labor market has hardly loosened up so far. Reuters reported that the tight labor market made the Federal Reserve continue to tighten monetary policy, which aggravated the risk of economic recession next year. However, most economists believe that the recession may be short and mild.

　　Powell believes that it is still possible for the US economy to achieve a "soft landing", but the possibility of achieving this result is declining. (Reporter Liao Bingqing comprehensive report)

On April 25th, the column "Extraordinary Way" of Phoenix.com released Zhao Lusi’s interview feature film. When asked if there would be any pressure to cooperate with an old drama like WU GANG in the movie "The Back Wave", Zhao Lusi said that she was under pressure at first, because the whole drama was matched with very powerful old artists, and the second was that there were not many modern dramas she shot. But the pressure will be great for one day, and it will be fine on the day of the opening banquet. When the director introduced WU GANG to her, he directly said, "This is your daughter." Jiang Shan sat next to her and told her not to cross her legs. Old artists put her into that environment at once.

　　Zhejiang Online August 7 th (Reporter Shen Tingyu Jiang Xiaorong)The Paris Olympic Games is in full swing. Looking back at the Olympic history, the wonderful inside and outside the stadium, the charm of culture is fascinating. From the first Athens Olympic Games to the present Paris Olympic Games, what inspiration have we got from it?

　　The venue is integrated into cultural attractions.

　　From the beginning of the modern Olympics, we can see a strong cultural color.

　　In 1892, Coubertin, the father of modern Olympics, delivered a speech "Olympic Manifesto" at Sorbonne University in Paris. In this passionate speech, he linked sports with the spirit, ambition and customs of a nation.

　　Samaranch, the former president of the International Olympic Committee, said: "The biggest difference between the Olympic Games and other large-scale events is that it is a grand gathering combining sports and culture."

　　In 2024, when the Olympic Games came to Paris for the third time, this romantic city opened a new solution for the Olympic Games to show its culture with a groundbreaking new perspective. From many details, we can read the romance with rich French culture.

　　A purple track and field track. This bright purple in stade de france is called "lavender field in track and field". The most widely circulated folk saying is that this is "the inspiration brought by provence lavender Tian." At the moment, the Provence region is full of real flower fields, while the Paris venues are a different kind of flower fields.

　　The International Olympic Committee did not strictly stipulate the color of the runway, and the purple runway appeared for the first time in the history of the Olympic Games. As Allern Brandel, the sports manager in charge of the track and field of the Paris Olympic Games, said, "This is to provide a runway that is different from those we have seen before, and to maintain the creative practices that the organizing committee has been doing since its establishment and break the routine."

　　A flowing Seine. The opening ceremony of the modern Olympic Games was moved from the stadium to the urban space for the first time, which kicked off in Paris. With the whole city as the background, the river replaces the runway and the pier serves as the audience. This is a grand event across Paris.

　　Depart from the Ostritz Bridge, pass through Notre Dame de Paris, Louvre, Place de la Concorde, Grand Palace in Paris and other buildings, and finally arrive at troca Drouet Square on the other side of the Eiffel Tower. Along the way, French classic film and television operas and game works such as Phantom of the Opera, Assassin’s Creed, Les Miserables and Train Entering the Station have emerged constantly, and sports, history, literature and art are integrated.

　　One of the great innovations of this Olympic Games is to integrate a large number of competition venues into the famous cultural attractions in Paris. Watch beach volleyball at the foot of the Eiffel Tower, watch archery in the Invalides of the Military Museum, and watch equestrian in the Garden of Versailles … This time, more than 10 world-famous scenic spots in Paris have become Olympic venues. Here, the humanities, natural landscapes and sports events reflect each other, and watching the games can also touch on history.

　　Creativity builds emotional resonance bridge

　　The host of every Olympic Games understands that this is a stage to show its unique culture to the world. But it is not easy to show it well.

　　Rich cultural accumulation is the basis for the host to tell a good story. Different countries and regions have different cultural histories, so it is a challenge for the organizers of previous Olympic Games to let local culture go to the world with the help of the Olympic window.

　　In the road cycling men’s road race that just ended not long ago, 90 road racers from all over the world set off from troca Dro Square and completed a 273-kilometer ride. Along the way, we can see the Eiffel Tower, Versailles and other landmark buildings. This is an extreme challenge to endurance and speed, and it is also an unlock to the natural and humanistic beauty of Paris.

　　Intelligent high technology makes the cultural charm of the Olympic Games shine even more. From the previous LED system, the ground lifting stage, to the current artificial intelligence technology and virtual human guests, every Olympic Games always uses the cutting-edge new technology at that time to make sports and culture collide with different sparks. AI technology has been widely used in this Olympic Games, realizing the experience of immersive 360-degree live broadcast.

　　Enough creativity, invisibly built a bridge of emotional resonance. In 1924, women were officially allowed to participate in the Paris Olympic Games. In 2024, 10 golden female statues slowly rose from the water at the opening ceremony to pay tribute to outstanding female representatives in French history. This is a dialogue after a hundred years.

　　Behind creativity, it reflects the light of humanity.

　　Create a global cultural exchange business card

　　With sports as the carrier, nowadays, the Olympic Games has become a worldwide cultural wealth. The enlightenment of the Olympic Games goes far beyond the Olympic Games. It has further inspired us to culture and sports, as well as the interdependence and common prosperity between different cultures.

　　The boundary between culture and sports can be bridged. The Paris Olympic Organizing Committee put forward the concept of "Cultural Olympics". This year, the Paris Olympic Cultural Committee held thousands of activities in various parts of France, which will last until September 8, and is committed to promoting communication and exchanges in different fields by integrating art and sports. Walking on the streets of Paris, from the Louvre to the community park, you can inadvertently see an art exhibition about the Olympic Games.

　　Inside and outside the stadium, everyone is a tiny incision for the cultures of various countries to go global. Previously, China table tennis player Malone was snapped up by athletes from all over the world in Paris, and was called "the 5A-level punch point of the Olympic Games" by netizens, which also made him a bridge to communicate Chinese and Western cultures and spread friendship. When athletes’ personal achievements and charm are combined with competitive sports spirit, a ready-made cultural exchange business card is created.

　　For more than 100 years, the vigorous vitality of the Olympic spirit in different groups, different countries and different regions is precisely because of its value consensus, common words and emotional resonance, as well as respect for different civilizations and cultures.

　　More than 100 years ago, Coubertin’s bold idea completed the revival of the Olympic Movement. On the Olympic stage, we expect future Olympic organizers to put on the wings of culture and hold more wonderful and creative events.

1905 movie network news The film released a preview of "Laughing and Flying", the old brother, the little brother and the new brother assembled in place, and the mentoring team of Caotai team returned to Bayinbuluke circuit, with endless laughter, which made you laugh and fly. The film was written and directed by the screenwriter, starring,,,, and, with a special performance and friendship. It was the strongest comedy lineup in the Spring Festival and was released nationwide on the first day of the New Year’s Day.

Zhang Chi, who broke down the driving school and revolutionized the grassroots team, took a conspicuous package of apprentices to "really practice skills"

The movie Pegasus 2 tells the story of Zhang Chi (Shen Teng), a driving school coach, and Li Xiaohai (Adam), a potential newcomer, who went to the last Bayinbuluke Rally with a lot of jokes. The "Laughing Soars" version is full of joy, and Shen Teng and other comedians are shaking their burdens wildly. Zhang Chi, a former champion driver, became a driving school coach with a whole set of injuries, leaving only Sun Yuqiang (Andrew) and "Old Brother" Ji Xing (Zhang Ben Yu) with him. Black powder’s bad comments continue to export "Bayinbuluke’s shame" and "black-hearted driving school coach", while the director of Laotoule Car Factory (Jia Bing), who is an iron powder, brings a godsend opportunity to reorganize the team. His bargaining skills are full, and his sponsorship fee is cut from 6 million to 4 million in one fell swoop, which is a punch in the punch. Zhang Chi talked about "I’m not a champion, but a driving school coach", and he was also nervous about buckling the wrong seat belt, rolling parking and other funny operations, but when he really got on the track, he regained his glory, which made people sigh that "this driving school really practiced technology". In addition, Zhang Chi’s two conspicuous Bao apprentices are also quite eye-catching. Li Xiaohai, the "little brother", is eye-catching with his unexpected driving talent, and Liu Xiande (Sean) keeps calling "Master" and cos the Monkey King, which shows his true colors.As the driving school explodes to change the motorcade, this grass-roots team, which is full of fun and chicken flying and dogs jumping, will go to the stadium with a lot of jokes, which is worth looking forward to.

Shen Teng Adam’s big screen first took the veteran newcomer mentoring file and went to the stadium to dream.

In the movie "Pegasus 2", Shen Teng and Adam partnered on the big screen for the first time, which attracted the attention of countless audiences. Zhang Chi, played by Shen Teng, returned to become a driving school coach in a state of blood deficit, but in the eyes of his supporters, he is still the "eternal king of Bayinbuluk". The addition of the new character Li Xiaohai also makes the new story more interesting. Adam said: "Li Xiaohai is a very resilient and ideal person. He worked as a test driver for many years before his early years and never had the opportunity to participate in the race as a racing driver. His biggest dream is to stand on this stage in Bayinbrook." In this trailer, Adam’s model of racing driver was officially exposed. He revealed that Han Han’s director has high requirements for the service road. When shooting in a real racing car, the four-point seat belt will be fastened tightly, and the helmet mask will easily squeeze his face out of shape, but it will be easier to enter the role of racing driver. When talking about Zhang Chi and Li Xiaohai, Shen Teng said that Li Xiaohai is a driver with equal talent and hard work, and Zhang Chi created an opportunity for him. Adam described "Master" Zhang Chi in three words: relaxation, body of work and inspirational. In the preview of "Laughing Soars", Li Xiaohai said, "Bayinbuluke, don’t you want to try again?" Just like a signal to ignite fighting spirit, Zhang Chi’s helplessness and unwillingness, Li Xiaohai’s resilience and dreams all point to Bayinbuluke Rally. What kind of running-in will the two go through,How will they achieve each other? See you at the cinema on New Year’s Day.

The film "Pegasus 2" is written and directed by Han Han, starring Shen Teng, Adam, Andrew, Zhang Ben Yu and Sean, featuring Wei Xiang and Jia Bing, and featuring Zheng Kai in friendship. It will be released nationwide on New Year’s Day.

　　The Legislative Council of the Hong Kong Special Administrative Region unanimously passed the "Regulations on Safeguarding National Security" and successfully completed the legislation of Article 23 of the Hong Kong Basic Law, which inspired all sectors of the community in the SAR. On the 20th, headlines such as "Fulfilling the Glorious Mission" and "Opening a New Chapter in Hong Kong" occupied the headlines of major newspapers in Hong Kong, and major political groups, associations, chambers of commerce and professional organizations expressed their full support for the passage of the Ordinance in different ways. Everyone has said that with a solid foundation for safeguarding national security, Hong Kong can stride forward at full speed on the road from rule to prosperity and move towards a brighter future.

　　This is a historic moment for Hong Kong. After the Hong Kong National Security Ordinance was unanimously passed, Chief Executive Lee Ka Chiu John said that the constitutional responsibility and historical mission of the SAR had finally been fulfilled and national security had been effectively guaranteed. People clearly remember that after the establishment of the Hong Kong Special Administrative Region, due to the constant "stigmatization" and "demonization" of anti-China and external hostile forces, the legislation of Article 23 of the Basic Law was delayed, which became a major loophole in the SAR’s maintenance of national security and a major defect in the implementation of the Basic Law. During the legislative deliberation, Mrs. Ye Liushu-yi expressed her feelings that she was very happy to come to this step and shoulder greater responsibilities this time. Member Liao Changjiang said that it has become a broad consensus in society to complete legislation as soon as possible to fill the shortcomings of Hong Kong in safeguarding national security; Member Shang Hailong said, "Today’s stable and peaceful social environment is hard to come by, so we should cherish and maintain it!" … … Members of the Legislative Council’s speeches have aroused strong resonance in Hong Kong society. The general public who have experienced a major turning point from chaos to governance feel more truly that the successful completion of Article 23 legislation is another landmark event since Hong Kong’s return to the motherland, and they are deeply honored and encouraged.

　　The smooth passage of the Hong Kong National Security Ordinance has provided a more solid institutional guarantee for maintaining the long-term prosperity and stability of the SAR. While effectively safeguarding national security, the regulations have created a more stable and predictable development environment for Hong Kong. Representatives of Hong Kong’s industrial and commercial circles pointed out that eliminating the uncertainty in the field of national security will consolidate and enhance the overall business environment in Hong Kong, better attract industrial and commercial enterprises and investors to set up businesses in Hong Kong, and make Hong Kong continue to be a "paradise for entrepreneurs and a place to realize their dreams". During the interview, many Hong Kong residents said that they cherish the stable and stable life now, and the 23 laws have made them more confident about the future of Hong Kong. Public opinion in Hong Kong generally believes that without worries, Hong Kong can go into battle lightly, focus on developing the economy and improving people’s livelihood, and jointly create a more prosperous and better home.

　　Hong Kong’s national security regulations conform to the will of the people, ensure security and protect development, lay a solid foundation for the SAR to safeguard national security, and consolidate the "retaining wall" of Hong Kong from chaos to governance, which will surely promote Hong Kong’s accelerated realization of governance and prosperity. With a high level of security, Hong Kong’s unique position and advantages will be more prominent, and the tremendous creativity and development vitality contained in society will be fully released. In the new era and new journey, the pace of high-quality development in Hong Kong will surely be vigorous, and the prospects of the SAR will be bright.