I finally got off work-

You look at the crowded subway, sigh and stick it up. When you get home, you can unload your fatigue, open a hit drama and enjoy the rare free time.

This is the spiritual comfort of contemporary migrant workers-binge-watching.

But these spiritual foods are often uneven, especially seasonal dramas, which can be called unfinished professional households:

One season reached its peak, the level declined in two seasons, and the three seasons were beyond recognition …

Is there a season drama that breaks the curse of the rotten end?

There is!

Ten years, it’s as usual-

When the ninth season started, it still got a high score of 9.3. What’s the secret?

NO, "The Lonely Gourmet" not only doesn’t have a secret book to keep it hot, but even the story is very simple. It has been telling the same thing for nine seasons-

One is calledKogoro, head of the wellA grocer (decorated by YUTAKA MATSUSHIGE) looks for delicious food during work breaks.

The story of Goro and food has also become the youth of many people, and every season, some people are willing to come again for hundreds of millions of times.

At the beginning of the ninth season, Wu Shu, who has not seen for a long time, stood at the door of the food store, and his memories popped up instantly.

"Knocked-"

Uncle Wu, who just finished the negotiation, is hungry.

This familiar picture, my DNA also moved …

Uncle Wu found a small shop that fried pork chops, and watched the diners in the shop feasting. Uncle Wu’s greedy worm was completely hooked up.

Not much to say, let’s have one firstFried pork chop with loin meat——

The crispy shell is wrapped in thick pork chops, topped with sauce, and the meat flavor and sauce blend perfectly, which is the top enjoyment of taste buds.

Second mealGolden fishWonderful, the soft fish fully absorbs the sauce, picks up a piece and chews it carefully, and the fresh fragrance of the fish rolls in the mouth, absolutely!

Not only can you learn about Japanese food with Uncle Wu, but you can also see Uncle Wu occasionally.Tasting European food.

This time, Uncle Wu brought us here.Greece.

Greek cuisine is not on the same channel as East Asia in terms of material selection, and it is full of strong European flavor.

Can you imagine that grape leaves can also be made into food? !

Uncle Wu still played his gift of eating ~

Pour lemon juice, and the acidity will be enhanced, which is another flavor.

In addition to foreign food, The Lonely Gourmet also has an essential link-Chinese cooking.

This time, Uncle Wu ateGuizhou cuisineGuizhou cuisine is spicy and delicious, which is quite different from that in Sichuan and Chongqing.

This dish of Sichuan style pork is rich in color and fragrance, and the fat but not greasy meat slices are mixed with the fragrance brought by pepper, which is spicy and cool!

How can there be no lobster sauce hot pot in Guizhou restaurant?

Amorphophallus konjac, baby cabbage, Flammulina velutipes, potato chips, thousand pages of tofu …

There is also a hot pot standard-mutton.

The steaming picture is matched with Wu Shu’s inner monologue, and the smell of hot pot seems to have overflowed the screen ~

Uncle Wu’s monologue when eating hot pot is a deep understanding of hot pot.

The spicy and refreshing feeling stimulates the taste buds, and even if you sweat, you won’t give up the delicious taste. This feeling can be accurately described only by "enter the dragon", which is not bad.

The subtle metaphor makes the food come alive instantly.Every psychological activity is a prelude to the strategy of food, and it is the pure attitude towards food that makes The Lonely Gourmet become a drama for many people.

And this thing, once done, is ten years.

"Lonely Gourmet" was launched in 2012, and it has been ten years since then. Uncle Wu has also moved from middle age to old age.

This foodie uncle who is rich in inner drama and likes to gossip is the youth of many people. Seeing him eating with relish will ease his gloomy mood.

We are used to "I’m so hungry!" after Uncle Wu’s discussion. ;

I also know that after he enters the store, he will make a choice phobia in the face of dazzling food;

When enjoying food, he can always find an accurate description of the angle and let the audience be there.

It seems that everything is used to it, but in fact it can’t be separated from the actors’ efforts.

YUTAKA MATSUSHIGE won’t eat for a whole day before each shooting, and only in this way will he feel ecstatic when shooting.

This season’s filming is particularly difficult. During the epidemic, YUTAKA MATSUSHIGE wore a mask and shuttled through the food store, and also spoke frankly about the impact of the epidemic on the catering industry.

In addition, there is no ups and downs in the whole drama, and no characters have cooperated with YUTAKA MATSUSHIGE for a long time. The drama is supported by the strength of the actors.

In the play, Uncle Wu is looking for food alone. Off-stage, it was YUTAKA MATSUSHIGE who made a one-man play for ten years.

Uncle Wu and YUTAKA MATSUSHIGE have a certain degree of overlap, and at some point, they are all lonely.

Although the characters and plot of Lonely Gourmet are slightly thin and the shooting environment of the ninth season is not ideal, itStill holding the purity of food, coming to us with a cure..

The Lonely Gourmet lasted for many years and gained a large number of loyal audiences.

There is nothing but-healing in resonance.

Uncle Wu is actually a microcosm of modern people.

The people behind him are more in the cubicle, in the assembly line and on the way to work.

Modern life divides everyone into independent individuals, and the more people travel alone in the stream of people.

Sometimes it seems like calling friends, but the deep loneliness is lingering, which is a common fault of modern people.

Lonely is not a gourmet, but you and I who hurried home after the lights went out.

The reality is a little sad, but the appearance of Uncle Wu saved the sorrow.

"Lonely Gourmet" perfectly hides the tired side of Uncle Wu under the delicious food, seemingly enjoying the delicious food, but actually curing loneliness.

In the only free time, I throw away all my troubles and eat without distractions, which not only makes my stomach full but also decompresses.

just asThe beginning of each episode——

The pictures in this article are from the Internet. If there is any infringement, please contact and delete.

Being separated from the world during food time, gaining temporary spiritual freedom and eating well are the lowest cost sources of happiness.

So, did you have a good meal today?

On August 23, Hunan police announced a major case of cross-border telecom fraud using cryptocurrency. The case involved renting communication tools to overseas fraud gangs, involving more than 4 million yuan. The Ouyi wallet address of Xia Mou, the leader of the criminal gang, shows that the encrypted currency used to settle the fraudulent commission is as high as 9 million yuan, nearly 10 million yuan. The gang members mainly trade through the virtual currency USDT to avoid traditional financial supervision.

Wen Jie, deputy head of the new crime investigation brigade of telecommunication network of Linwu County Public Security Bureau, revealed that criminal gangs provide services to overseas fraudsters through "mobile phone port" and "PC terminal". "Mobile phone port" refers to renting a mobile phone number to make fraudulent calls, while "PC side" refers to renting a micro signal for fraud. It is worth noting that the gang members are generally younger, many of them are minors under the age of 18, and they are tempted by high salaries to participate in criminal activities.

The police found detailed records in the suspect’s computer, including the contact information of the merchant, the QQ of the crime, the time and the transaction method. The case involved 86 cities in 18 provinces, and 62 suspects were arrested. The police reminded that criminals use cryptocurrency to evade supervision, and the public should be vigilant and beware of new financial fraud.

Qin Yongcheng’s "First Oil Well" in Daqing Oilfield. Pictures are data pictures.

Qin Yongcheng (right) is with oil workers in Panjin Oilfield. Pictures are data pictures.

　　[Great motherland, unforgettable songs].

　　"Splendid rivers and mountains are picturesque, and the motherland is building a cross-horse. It’s a great honor for me to be an oil worker and travel around the world wearing an aluminum helmet … …” This heroic ode to oil workers is not only a clarion call to encourage oil workers from generation to generation to join in the construction of the motherland, but also an overall portrayal of the outstanding heroes of the working class in China. Although it was written more than half a century ago, it is still so exciting and exciting to sing today.

　　The composer Qin Yongcheng (1933— 2015) is the first generation composer trained in New China. During more than half a century’s creative career, he has created a large number of musical works with high artistic achievements and wide social influence, such as the song "I offer oil for the motherland", "Chairman Mao travels all over the motherland", My People，My Country, vocal concerto "Haiyan", symphonic poem "Two Little Cowboys" and movie music "Entrepreneurship" and "Marshal and Soldiers". He made great contributions to the music, art and education in our country all his life.

　　Three days with the "Iron Man"

　　In 1964, a notice brought Qin Yongcheng into close contact with Li Jiefu, a famous composer and president of Shenyang Conservatory of Music. It was this notice that made him have an indissoluble bond with oil workers all his life. In March this year, China Musicians Association organized some composers to experience life in Daqing Oilfield and created a batch of works reflecting oil workers. Dean Hijacking also received a notice, asking him to report to Sarthou, Heilongjiang Province on March 20th. After receiving the notice, the dean of the robbery immediately made preparations for leaving. Due to physical reasons, the college is going to find a young man to accompany the dean of the robbery to "go north". At the suggestion of the dean of the robbery, Qin Yongcheng will accompany him. Unfortunately, Qin Yongcheng was suffering from a high fever and had been in bed for three days. Upon hearing this, Dean Hijacking personally visited Qin Yongcheng’s home and told him to rest at ease for illness. In the face of this rare opportunity, Qin Yongcheng looked forward to his early recovery. Although his fever had gone down the next day, he was still very weak, and insisted on accompanying Dean Jiefu.

　　On the evening of 19th, Qin Yongcheng got his wish and boarded the train to the north. In the car, Qin Yongcheng finally put forward the question that was hidden in his heart: "Where are we going to Sarthou?" Dean Hijacking told him quietly: "Sarthou is a big oil field, called Daqing Oilfield, and it is still confidential." After moving to Daqing, Qin Yongcheng lived with many famous musicians such as Lv Ji, Qu Wei, Wang Xin, Zhang Lu and Jiefu in the guest house of Daqing Petroleum Command.

　　Since the next day, the oil field has arranged courses for musicians to introduce oil-related knowledge, from exploration and drilling to oil production and refining for ten days, with one content per day. Ten days later, the oilfield arranged for them to experience life in the first line. Qin Yongcheng, Jiefu and Wang Xin (songwriters of "Singing the Motherland") were assigned to the "1205 Hero Drilling Team" with Wang Jinxi, the "Iron Man", and lived together with the "Iron Man" for three days. During this period, Wang Jinxi told Qin Yongcheng that when he held a People’s Congress in Beijing in 1959, he saw that the buses in Beijing were in a heavy mood because of lack of oil and carrying gas bags. He also listened to him tell the story of the Daqing Petroleum Congress. In the spring of 1960, Wang Jinxi’s drilling team was in Yumen Oilfield. When it was heard that a large oil field had been discovered in the north, the whole country was going to hold a general meeting there, and immediately asked the superior to fight. They said goodbye to their relatives and boarded the train going north in their light clothes. Faced with the harsh climate, hard living and working environment, and poor equipment, oil workers shouted the loud slogan of "if you have the conditions, you should go if you don’t have the conditions" in order to get rid of the label of "poor oil" as soon as possible and break the economic blockade of western hostile forces. "When the oil workers roar, the earth will shake three times."Qin Yongcheng’s soul was strongly shocked and greatly impacted by his earth-shattering fearless revolutionary heroism. Especially in the days spent with Wang Jinxi and his heroic drilling crew, Qin Yongcheng’s understanding of oil workers has been greatly sublimated, and he has a strong emotional resonance. He is determined to create works that can reflect the spirit of oil workers to express his high respect for them.

　　A masterpiece completed in the canteen of the hostel.

　　After three days of experience, Qin Yongcheng returned to the guest house, and the Propaganda Department of the Party Committee of the Oilfield prepared a batch of lyrics reflecting the work and life of Daqing Oilfield and oil workers for them, hoping that composers would compose music for them. After the old composers had chosen the lyrics, Qin Yongcheng also chose them. At this time, a lyric jumped into his eyes, which was written by oil worker Xue Zhuguo, "I offer oil for my motherland." This first-person lyric is vivid and vivid, which vividly depicts the heroic and optimistic mood of oil workers and the fearless revolutionary spirit of fighting against the world. The more Qin Yongcheng watched it, the more he liked it. The more he watched it, the more excited he became. At this moment, he was inspired and full of thoughts. In the canteen of the hostel, he finished writing this work in just 20 minutes.

　　Inspired by the artistic conception of the lyrics, the prelude of the song adopts a fast speed, a lively and elastic rhythm, and a fluctuating melody line, like a train full of oil workers galloping in the splendid rivers and mountains of the motherland, from the northwest of the motherland to the northeast thousands of miles away. Then, the heroic song of the oil workers was introduced: "The beautiful rivers and mountains are picturesque, and the motherland is building a beautiful horse. I am honored to be an oil worker and wear an aluminum helmet to travel all over the world." The melody of the song is broad, fresh and smooth, which vividly depicts the bold spirit of oil workers and the revolutionary optimism full of pride and self-confidence. On the word "kua" of "kua steed", the melody absorbs the elements of rap music and adopts a sliding tone, which is not only in line with the rhyme of Chinese four tones but also forceful, and can better highlight the bold and hearty character of oil workers. These four sentences are lyrical paragraphs, which vividly depict the heroic fighting spirit and optimistic spirit of oil workers moving to the north and south and being at home all over the world.

　　In order to show the dauntless heroism spirit and heroic spirit of oil workers, who are "fearless of heaven, fearless of earth, and fearless of storm, thunder and lightning", Qin Yongcheng treated these two lyrics into short and powerful eight-point dotted notes and syncopated rhythm, which made the music more powerful and dynamic. At the same time, it not only forms a sharp contrast with the previous lyric paragraphs, but also lays a good foundation for the climax of the whole song that appears later.

　　The climax of the song is in the last two phrases, "I contribute oil to my motherland, where there is oil, my home is there". In order to make the climax of the song more prominent and infectious, Qin Yongcheng ingeniously treated the first beat at the beginning of this sentence as a rest, and started the word "I am" from the weak beat to highlight the word "ancestor" in the next section. Then, on the word "oil" for "offering oil", the melody adopts a circuitous upward movement, forming a large-span 10-degree interval in the range. In the last four bars of the song, Qin Yongcheng skillfully used the drawl of China’s traditional opera music for reference. It is worth mentioning that in the first draft of the work, the last four sections are not like this, but after Qin Yongcheng returned to school, he sang the work to friends and students, listened to and adopted everyone’s suggestions, and changed the original last simple melody into the current one-stop drawl. In this way, the music is more infectious and dynamic, which not only depicts the free and easy character of oil workers, but also makes the whole song end in an atmosphere full of optimism and pride. The revised work was published in the journal "Music Life" of Liaoning Branch of China Music Association, which soon became a hero’s ode to oil workers in the north and south of the motherland and inside and outside the Great Wall.

　　The only "composer of oil workers"

　　The first singer of this song, Liu Bingyi, a famous baritone singer of the former Central Orchestra, also played an important role in the promotion of this song. He and Qin Yongcheng also became attached to this song, and it was sung for 50 years. And Qin Yongcheng also started from this song, and successively created a number of excellent works reflecting oil workers. In 1973, as a key project of the Ministry of Culture, Changying filmed a feature film "Entrepreneurship" reflecting the Daqing Petroleum Congress, and specially invited Qin Yongcheng to create music for this film. Qin Yongcheng lived up to expectations, and created a number of well-known songs in his film music, such as Looking at Beijing with deep feelings, Entrepreneurial songs, and The Fragrance of Oil in Tianya Wan Li. Because of Qin Yongcheng’s outstanding contribution to the creation of oil-related music, the vast number of oil workers are familiar with the name Qin Yongcheng and affectionately call him "the composer of oil workers". In 1994, China Petroleum and Natural Gas Corporation (formerly the Ministry of Petroleum Industry) awarded Qin Yongcheng the honorary title of "composer of oil workers", and he was the only composer in China to win this honor. In 1996, China Records Corporation awarded Qin Yongcheng the "Golden Record Award" for this work, which was later included in the 20th century Chinese classics.

　　Praising the motherland and people and eulogizing the times and life are the themes of Qin Yongcheng’s life creation. It is precisely because of Qin Yongcheng’s deep patriotism, deep thoughts and feelings for the broad masses of the people, including oil workers, rich musical language based on Chinese excellent musical culture, and continuous absorption of rich nutrition and creative sources in the long-term in-depth social life that he created such immortal masterpieces represented by "I Contribute Oil to the Motherland", which are full of positive energy and the main theme of the times, and have high artistic value and appeal to both refined and popular tastes. (Author: Wei Huang, former vice president and second-level professor of Shenyang Conservatory of Music)

1905 movie network news The movie key, which is directed by the screenwriter and starring,, and will be extended to February 28. As of 22:00 on January 18th, the cumulative box office of the film was 844 million yuan, winning the single-day box office champion for 18 consecutive days.

The annual meeting can’t stop! It tells the story that fitter Hu Jianlin was transferred to the group headquarters by mistake and became a gold collar. At the annual meeting of the group, he exposed the corrupt executives of the factory and finally saved the factory. The film’s joyful irony of the strange phenomenon in the workplace has deeply resonated with countless migrant workers, helping them to climb their reputation. Douban scored as high as 8.2, making it the highest domestic comedy in Douban in the past five years.

Through ten groups of questions and answers, this paper gives you the function and application of popular science stem cells, and shows you the important position of stem cell therapy in modern medical care.

Mother, the pilot of the boat of life, not only gave birth to us, but also promoted the reproduction of mankind. She is a great inheritor of life and a transmitter of love.

Cells, the weavers of the web of life, constitute the cornerstone of the human body, which is a miracle exhibitor with various forms and complicated functions.

The human body is a magnificent movement interwoven with countless cells, the harmonious resonance of 240 kinds and 60 trillion cells, and the subtle fusion of 4 major organizations, 36 organs and 8 major systems.

She is a special cell, but also the guardian of the source of life. She can regenerate new cells, replace aging cells and repair damaged tissues and organs. She is the mother of the cell world.

This kind of cell is the root of our life-stem cells.

With the progress of science, stem cell research has become one of the most advanced and active research directions in the global medical field.

However, for the general public, what exactly are stem cells? What does it do? What kind of people are suitable for repair intervention through stem cells? What are the risks even in treatment? This article will help you understand these questions easily through ten groups of questions and answers.

Ten questions and answers about stem cells

01

What are stem cells?

Stem cells are cells with self-renewal function and multi-directional differentiation ability.

Under certain conditions, these cells can differentiate into more than 220 different functional cells in human body. Because of its remarkable homing effect, stem cells can repair and replace damaged cells and promote organ regeneration. They are the basic cells that constitute various tissues and organs of the human body, so they are known as "the source of life" and are often called "universal cells" in the medical field.

02

What are the classifications of stem cells?

Scientific research shows that stem cells exist not only in embryos, but also in adults, which can be extracted from cord blood, umbilical cord, placenta, bone marrow, fat and other tissues.

Stem cells are divided into totipotent stem cells, pluripotent stem cells and unipotent stem cells according to their extensive differentiation ability.

Stem cells can be divided into embryonic stem cells and adult stem cells according to their stages of embryonic development.

According to the tissue type of stem cell differentiation, it can be divided into hematopoietic stem cells and mesenchymal stem cells.

03

What is stem cell therapy?

"Stem cell therapy" refers to a medical intervention that extracts stem cells from patients or uses other stem cells, cultivates them under laboratory conditions, and then transfuses them into patients through specific transplantation techniques, so as to repair the cells and tissues that have lost their functions, thus promoting their regeneration and improving their symptoms. At present, hematopoietic stem cells and mesenchymal stem cells are widely used in clinic.

04

What is the difference between autologous and allogeneic stem cells?

Autologous stem cells are derived from patients themselves, which have perfect tissue compatibility, no need for matching, high utilization rate of transplanted cells and no rejection.

Allogeneic stem cells are derived from individuals other than patients and have low immunogenicity. Autologous stem cells are not recommended for people with infectious diseases, major genetic diseases or other health problems.

05

How can stem cells be used to treat diseases?

Cells are the basic unit of life. Human life is accompanied by the process of self-replication and differentiation of stem cells from birth to growth. The ability of stem cells to treat diseases mainly stems from their biological characteristics, which include:

The ability of long-term survival and continuous self-replication;

It can differentiate across different lines and germ layers, showing high plasticity;

And its chemical tendency, that is, homing effect, provides an important biological basis for cell therapy.

06

Is stem cell therapy risky?

Compared with conventional drug therapy, stem cell therapy is considered safer and has fewer side effects. But this does not mean that the risk is zero. Looking at stem cell therapy objectively, the following are some main risks of stem cell therapy:

Tumor development: If stem cells divide or differentiate into abnormal cells uncontrollably, it may lead to cancer. This mainly applies to embryonic or fetal stem cells, or reprogrammed stem cells, because the risk is based on their pluripotency.

Immune rejection: The body may regard foreign stem cells as a threat and attack them, leading to inflammation and injury. This is more likely to happen in hematopoietic stem cells (HSC).

Infection or complications related to invasive medical procedures: Stem cell therapy may lead to infection or complications related to invasive medical procedures.

Drug interaction: Stem cell therapy may have unpredictable interactions with other drugs taken by patients, which may lead to adverse drug interactions.

Unconfirmed or untested stem cell therapy: There is also the risk that unscrupulous practitioners provide unconfirmed or untested stem cell therapy, which may be unsafe or effective.

The effect of treatment is uncertain: patients should also realize that stem cell therapy does not guarantee a cure, and in some cases, it may not be effective at all. Stem cell therapy may not provide lasting results, and patients may need additional treatment.

It should be noted that these risks may be different due to individual differences, treatment methods, stem cell types and other factors. Before receiving stem cell therapy, patients should fully discuss these risks with doctors and weigh the potential benefits and risks of treatment.

07

What diseases can stem cell therapy treat?

Stem cell therapy is mainly used in the fields of treatment, health care and beauty, and it is also used to improve some refractory diseases.

Heart disease: Stem cells can regenerate damaged heart cells and maintain the health and vitality of the heart through a specific process of induced differentiation in the treatment of heart disease.

Prevention and treatment of Alzheimer’s disease: Injecting induced differentiated stem cells can replace aging brain cells and improve cognitive function.

Treatment of liver cirrhosis: generate liver cells through differentiation, and promote the regeneration and repair of liver cells.

Cancer treatment: Directionally differentiated stem cells can enhance the body’s immune function and help fight tumors.

Treatment of premature ovarian failure: Stem cell therapy can restore ovarian function, promote the repair of damaged tissues, improve ovarian microenvironment, enhance reproductive capacity, prevent follicular atresia and promote follicular renewal.

Male hypofunction: Stem cell therapy can repair the aging of reproductive system, improve sexual function, maintain the balance of sex hormones, reduce nocturia, relieve the symptoms of prostatic hyperplasia, and help prevent prostate hypertrophy and other problems.

Enhance muscle function: with the increase of age, muscle function weakens, strength and relaxation function decline, and the body is bloated. Stem cell therapy can improve muscle function, enhance strength, improve body shape and show youthfulness.

08

What is the effect of stem cell therapy?

Stem cell therapy can be carried out by systemic infusion or fixed-point intervention. Clinicians adopt appropriate cell types and treatment strategies according to patients’ health status and disease needs.

Because this treatment can directly intervene in the cause of disease, avoid other physical injuries that may be caused by drugs and surgery, and help regulate the sub-health state, the effect is usually not limited to treating diseases, but also improving the overall function.

09

Is there an age limit for stem cell transfusion?

Traditionally, some types of stem cell transplantation, such as allogeneic bone marrow transplantation, often have age restrictions, and it is usually recommended to be 50 years old or under 45 years old. However, with the progress of medical technology, this limitation is being broken.

For example, it has been reported that a 71-year-old patient successfully received autologous hematopoietic stem cell transplantation, and a 69-year-old woman also successfully received her son’s hematopoietic stem cell transplantation.

These cases show that under proper medical conditions and monitoring, elderly patients may also successfully receive stem cell transfusion therapy, which proves that the age limit is gradually relaxing.

10

What are the taboo populations of stem cells?

Patients with advanced malignant brain tumors, especially brain tumors;

Patients with shock or general failure with abnormal vital signs (requiring disease correction) and those who do not cooperate with the examination;

Patients with heart, lung, liver, kidney and other important organ dysfunction (multiple organ dysfunction syndrome);

Patients with dysfunction of coagulation mechanism;

Patients with severe local infection;

Patients with positive serological results (such as HIV, hepatitis B, syphilis, etc.);

People with high allergic constitution or severe allergic history;

People with nervous system diseases or diseases that have not been diagnosed;

This group is in a special situation and has uncontrollable risks, so it needs careful diagnosis and treatment.

Write it at the end

Stem cells have excellent regeneration and repair functions, and these abilities will gradually weaken with age. Therefore, it is an increasingly popular choice to store healthy stem cells as early as possible, which will provide the possibility for future health management and disease treatment.

The 21st century will be the era of cell therapy, and the application of stem cells and immune cells is expected to play an important role in clinical treatment.

However, at present, except for the mature clinical application of hematopoietic stem cell transplantation, other types of stem cell therapy are mostly in the research stage, and strictly designed clinical trials are needed to prove their clinical advantages, safety and effectiveness, which need further study.

Moreover, non-compliant and eager stem cell therapy and research not only threaten the safety of patients, but also hinder the improvement of stem cell therapy and its research level, which needs the attention of legal supervision, and patients with hope in stem cell therapy should also be alert to fraud and pay attention to its development and related policies and regulations.

Original title: "Why do you call her" the mother of cells ":Ten questions and ten answers about stem cells, and learn about her magic with you"

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　　Multiple social apps can still be used normally without "real-name authentication". Insiders suggest that the youth mode should be turned on by default.

　　Recently, many netizens found and reported that some dating software is not strict with the use of minors. The Beijing Youth Daily reporter found that when using multiple strangers’ dating software, there is no need for real-name authentication, and minors can use these strangers’ social software "unimpeded". It is particularly noteworthy that in terms of function, there is no difference between unauthenticated accounts and other accounts, and accounts without real-name authentication can also purchase adult products at will. In this regard, many people in the industry have suggested that the youth mode can be turned on by default when the user does not log in with an ID card.

　　find

　　Multiple social App users can also be rewarded without real-name authentication.

　　The reporter of Beiqing Daily recently found that many social apps, such as soul, Detective, Momo, etc., can be used normally by simply choosing to log in with WeChat or mobile phone number without "real-name authentication".

　　These platforms all suggest that users must be over 18 years old when registering. For example, after soul registers, users need to choose the date of birth, but users can enter the interface without hindrance by filling in a date over 18 years old at will. Among them, soul needs to use a virtual avatar, and exploration and Momo need to add a real and clear avatar.

　　In the process of use, the above App will send a pop-up window in teenager mode to the user. The reporter of Beiqing Daily noticed that the youth mode entering Soul needs real-name authentication, and people’s faces will be dynamically recognized during the authentication process. After the tester enters his real name information, he can’t enter the teenager mode again. The teenage mode of exploring and momo is to set the password directly.

　　In view of the fact that it can be used normally without real-name authentication, Momo customer service responded: "Some functions need real-name use." When asked which functions will be affected by not having a real name, the customer service did not give a positive answer. In addition, regarding whether the real name will restrict consumption, the customer service said: "No real name will not restrict consumption."

　　When using the live reward function of Detective and Momo, even the account without real-name authentication will automatically jump to WeChat or Alipay.

　　In terms of recharge, none of the above three softwares has relevant restrictions or secondary verification for minors. And there is no real name account and unlimited consumption, which can recharge the highest amount of soul coins, exploration coins, momo coins and VIP recharge.

　　experience

　　Push content is undifferentiated, making friends and shopping are not affected.

　　The reporter of Beiqing Daily used an account without real-name authentication on a dating software, and marked "the second day" in the introduction. After searching for keywords such as "making friends in junior high school", "sexy underwear" and "adult products" on the home page, a lot of related push content appeared. The purchase of goods can automatically jump to WeChat or Alipay. In other words, if minors are not authenticated in this platform, it will not affect their use.

　　After several keyword searches, Beiqing Daily reporter used the test account to open the above-mentioned dating software again, and the homepage push also became the corresponding content related to keywords, in which minor dating also appeared directly and many times. In the shopping column, most of the products pushed also meet the previous keywords.

　　In the actual measurement, the reporter of Beiqing Daily also found that there are multiple video platforms in the youth protection mode, and the platforms will impose restrictions on young users in terms of content, usage duration and consumption.

　　For example, the daily use time should not exceed 40 minutes, and it is forbidden to use the software from the evening to the next morning, and it is impossible to open or watch the live broadcast, reward, recharge, cash withdrawal and so on. For example, a survey shows that in the youth mode, except for the functions of mobile phone recharge and city service, other functions of life service, transportation and shopping consumption are all disabled, while the functions of financial management are directly hidden. Aauto Quicker and Tik Tok, short video applications, banned teenagers from watching live broadcasts, which fundamentally prevented the risk of teenagers’ recharge and reward. Tik Tok also closed Tik Tok Mall. Video platforms Iqiyi, Tencent, Youku and Mango TV have closed the membership center and all other consumption channels such as financial welfare and games. Bilibili has also closed consumer operations such as membership purchase and top-up rewards.

　　suggestion

　　Directly open the youth mode for the unauthenticated netizen platform.

　　In response to the measured results of the reporter of Beiqing Daily, Professor Shang Jianhui, deputy dean of the School of Journalism and Communication of Hebei University, believes that the platform practice that has not yet imposed restrictions on young users does not conform to the norms. "According to the explicit requirements of the Regulations on the Protection of Minors’ Network (Draft for Comment) and the Regulations on the Protection of Children’s Personal Information Network, the network platform should formulate special rules and user agreements for the protection of children’s personal information. Therefore, this practice of the platform should be improved, otherwise it may cause harm such as premature maturity of children and deception of the network. "

　　Professor Shang suggested how to improve the platform’s protection measures for minors. "At present, there are some voices in academic circles. The index system of minors’ network protection includes 19 indicators in six dimensions, including information prompt, technical protection, anti-addiction (comprehensive) management, emergency complaint and reporting mechanism, privacy and personal information protection system, scientific popularization and publicity and education."

　　"Technical protection, information tips, scientific popularization and publicity and education are the weak links in the protection of minors on the Internet platform. The platform should first strengthen technical security protection and realize standardized management of the platform; Secondly, construct an omni-directional information prompt matrix to optimize the use environment of minors; Furthermore, practice the concept of multi-knowledge inclusiveness and do a good job in popular science and publicity and education; Finally, improve the youth model and enrich the content pool for minors. " Professor Shang said.

　　Some operators who did not want to be named told the reporter of Beiqing Daily that "registering with a mobile phone number does not mean real-name authentication. Operators will not synchronize all users’ personal information to all platforms at will. It is not excluded that operators cooperate with some larger platforms to authorize the platforms to identify information through mobile phone numbers, but only if both parties sign an agreement to ensure the other party’s safe storage and standardized use of personal information. Therefore, it cannot be said that registering with a real-name mobile phone number is equivalent to real-name authentication. "

　　Earlier, Jiang Yaodong, member of Chinese People’s Political Consultative Conference and former vice president of China University of Mining and Technology (Beijing), also suggested that "for users who have not been authenticated, the platform can default the user to enter the youth mode, which can protect minors from browsing age-appropriate content to the greatest extent."

　　interlinkage

　　According to public data, in 2021, the number of underage netizens in China reached 191 million, and the Internet penetration rate of minors reached 96.8%. According to a survey released by Beijing Internet Court, from June 2022 to May 2023, Beijing Internet Court accepted a total of 143 civil disputes involving minors, and the number of cases increased year by year, with game recharge and live rewards accounting for the largest proportion. Among them, the phenomenon that minors involved in litigation evade family supervision and anti-addiction measures is more prominent, and most minors evade family supervision and platform authentication measures. At the same time, minors are easily influenced by bad information. Some minors use the Internet to browse pornographic, bloody and violent bad content, and some minors are influenced by the online war and the "network water army" and learn to imitate bad online behavior.

　　Text/reporter Wen Wei Intern Li Yujie

　　Recently, researchers from China Academy of Sciences, Shenzhen Huada Institute of Life Sciences and other institutions have cultivated human pluripotent stem cells in a state similar to that of fertilized eggs developing for three days through somatic cell induction. This is the "youngest" human cell cultured in vitro in the world at present, and it is another subversive breakthrough in the field of regenerative medicine after scientists successfully induced human pluripotent stem cells. Related research results were published in the international academic journal Nature in the early morning of March 22nd, Beijing time.

　　It is understood that researchers have developed a non-transgenic, fast and controllable "cocktail" cell reprogramming method, which can transform human pluripotent stem cells into totipotent 8-cell embryonic-like cells, that is, totipotent stem cells equivalent to the three-day development of fertilized eggs. This achievement will help to realize the in vitro regeneration of human organs in the future, and it is of great significance to solve the problems of organ shortage, allograft and xenotransplantation rejection.

　　In 2012, the Nobel Prize in Physiology or Medicine was awarded to shinya yamanaka, a Japanese scientist who successfully induced mature somatic cells into pluripotent stem cells in blastocyst stage. The cells in human blastocyst stage are fertilized eggs developing 5-mdash; In the state of 6 days, its ability to further develop is limited.

　　However, this study has made a big step forward in this field, and for the first time, embryonic cells with fertilized eggs divided for only 3 days were obtained. In the early stage of fertilized egg development, great changes have taken place every day, and it is these 2-mdash; In 3 days, scientists obtained human 8-cell embryonic-like totipotent stem cells through in vitro induction for the first time. This is the "youngest" human cell induced in vitro so far, and it has very strong development potential. This study will also help to unlock the key to the early development of human embryos.

　　According to reports, these totipotent 8-cell embryonic-like cells reconstructed the embryonic state of fertilized eggs after only three times of division. Compared with pluripotent stem cells in the past, these cells can differentiate into placental tissues and may develop into more mature body tissues.

　　"This progress is also a model of the combination of regenerative medicine and single cell sequencing technology." Dr. Liu Longqi from Shenzhen Huada Institute of Life Sciences, one of the authors of the paper, said, "The efficient identification and mechanism analysis of cells or tissues obtained by stem cell technology in vitro or in vivo will greatly accelerate the development of regenerative medicine."

　　This is the first time that researchers have "transformed" human pluripotent stem cells into pluripotent embryonic cells in a real sense, so that people can reverse the "adult" version of cells into "infant" versions with more possibilities. At the same time, because the totipotent cells obtained this time are closer to the original state of early embryos, if they are used in regenerative medicine, the cultivated organs will be closer to the state of real organs, which is more conducive to transplantation.

　　This breakthrough is due to the progress of single cell sequencing technology. In the past, researchers may have to process and culture thousands of cells, and the probability of success is less than 10%. Nowadays, based on the single-cell library sequencing platform (DNBelab C4) independently developed by Huada University, combined with the DNBSEQ sequencing technology created by Huada Zhizhi, scientists can conduct multidimensional single-cell analysis with high sensitivity and accuracy, quickly obtain cells with important development potential, and study the development direction of these cells.

　　In this study, the research team also classified the induced pluripotent stem cells and injected them into mice for further development, and then used the single cell sequencing technology of Huada to conduct large-scale cell map analysis. Finally, the researchers confirmed that the experimental totipotent stem cells were highly similar to human 8-cell embryonic cells, which proved the totipotency of the cells. This provides a scientific basis for organ culture using patients’ own cells in the future and for organ transplantation and replacement.

　　The research was led by China Academy of Sciences and Shenzhen Huada Institute of Life Sciences, with the participation of several research teams including Cambridge University, Jilin University and rajshahi University. This study has passed the ethical review and strictly followed the corresponding laws and regulations and ethical standards.

　　On March 10th, the Education Bureau of Hengyang City, Hunan Province issued a notice saying that after comprehensive research, it was decided to adjust the items and time of the physical education examination of Hengyang junior high school academic level examination in 2023: the middle and long-distance race (1000m for men and 800m for women) in the basic test items was adjusted from compulsory examination to exemption examination, and all candidates in this project were given full marks.

　　This year, many places in the country have successively adjusted the plans for the senior high school entrance examination for physical education, and some places have adjusted endurance events such as long-distance running and swimming as optional items.

　　Among them, on March 8, Hangzhou Education Bureau released the latest adjustment plan for the 2023 senior high school entrance examination physical examination. So far, 11 districts and cities in Zhejiang Province have officially announced the sports programs for this year’s senior high school entrance examination, and the 1000-meter running (boys) /800-meter running (girls) projects have been adjusted to "can run or not".

　　The Paper noted that Lishui Education Bureau mentioned in answering questions from the public that candidates infected with novel coronavirus should carefully apply for physical endurance events such as 1000m (male) or 800m (female), and candidates who apply for such events should do a good job in personal health risk assessment.

　　Lishui City Education Bureau also reminded that candidates who have been infected with novel coronavirus and other special physique should pay attention to the recovery training of physical skills and gradually increase the difficulty intensity when preparing for the exam. Warm-up exercises should be done before training, physical condition should be paid attention to during training, and rest should be paid attention to in time after training. If necessary, give feedback to the teacher or parents about your physical condition. If you have difficulty breathing, abnormal heart rate or excessive fatigue, you should consult a professional doctor in time.

　　In Ji ‘an, Jiangxi Province, the notice issued by the Ji ‘an Municipal Education and Sports Bureau on March 6 stated that in 2023, there will be no compulsory items in the entrance examination for junior and middle school graduates, and the compulsory items (1000m for men/800m for women) will be adjusted to optional items. Candidates choose two items from five selected items for testing.

　　The Education and Sports Bureau of Ji ‘an said that all localities should fully understand the background and significance of the adjustment of this year’s physical examination items in the province, that is, from three items of the original examination to two items of the examination, and from the original compulsory examination items to optional examination items, so as to take effective measures to prevent major risks.

　　In addition, the "Notice on Doing a Good Job in the Physical Education Examination for Junior and Middle School Graduates in 2023" issued earlier by the Guangdong Provincial Department of Education also adjusted the compulsory items (men’s 1000 meters/women’s 800 meters and swimming) in the unified test project to optional items. The "Notice" pointed out that in view of the current epidemic situation in Guangdong Province and the physical health status of students, in order to effectively ensure the scientific, safe and smooth progress of the physical education examination for junior and middle school graduates in 2023, after in-depth analysis, comprehensive judgment and careful consideration, it was decided to make corresponding adjustments to the physical education entrance examination in Guangdong Province in 2023.