Notice of the Xicheng Park Management Committee of Zhongguancun Science Park on Amending the Detailed Rules for the Implementation of Several Provisions of Xicheng District of Beijing on Supporting th

Xike Guanfa [2023] No.2

All relevant enterprises and institutions:

  In order to better implement the Provisions of Beijing Xicheng District on Supporting the Independent Innovation of Zhongguancun Science Park Xicheng Park (No.1 of Westbound Regulation [2021]) and refine the relevant contents of the specific provisions, the Detailed Rules for the Implementation of the Provisions of Beijing Xicheng District on Supporting the Independent Innovation of Zhongguancun Science Park Xicheng Park (for Trial Implementation) (No.1 of Xike Guanfa [2023]) are hereby revised, please follow them.

Zhongguancun Science Park Xicheng Park Administrative Committee    

April 10, 2023  

Detailed Rules for the Implementation of Several Provisions of Xicheng District of Beijing on Supporting Independent Innovation of Zhongguancun Science Park Xicheng Park (for Trial Implementation) (2023 Revision)

  In order to implement the Provisions of Beijing Xicheng District on Supporting the Independent Innovation of Zhongguancun Science Park Xicheng Park (No.1 [2021] of Westbound Regulation) (hereinafter referred to as the "Several Provisions"), these Detailed Rules are formulated.

Article 1 Scope of application

  An enterprise that meets the following conditions may declare the corresponding provisions of Several Provisions:

  1. Zhongguancun high-tech enterprises registered and tax registered in the administrative area of Xicheng District, which have been recognized by Beijing Science and Technology Commission and Zhongguancun Science Park Management Committee in the year of policy fulfillment, and have applied for inclusion in the statistics of Xicheng Park of Zhongguancun Science Park (hereinafter referred to as "Xicheng Park") in the year of policy declaration;

  2. The science and technology enterprise incubator recognized by the Xicheng Park Management Committee of Zhongguancun Science Park (hereinafter referred to as "Xicheng Park Management Committee");

  3. Enterprises registered in the administrative area of Xicheng District, settled in Beijing, China Publishing Creative Industry Park (hereinafter referred to as "Publishing Park") and jointly recognized by Beijing Press, Publication, Radio, Film and Television Bureau and Xicheng Park Management Committee.

Article 2 Support independent innovation of enterprises

  I. Matching of major special funds for science and technology (Article 2 (1) of Several Provisions)

  (1) Category of supporting projects

  1. National projects

  (1) National Natural Science Foundation projects of the Ministry of Science and Technology (hereinafter referred to as "the Ministry of Science and Technology"), major national science and technology projects, key national R&D plans, technical innovation guidance projects, technical innovation funds for small and medium-sized enterprises, key new products, "Torch" plans, and major new drug creation (including projects approved by the Ministry of Health);

  (2) Industrial Internet innovation and development projects, electronic information industry development fund projects, Internet of Things, cloud computing and other emerging industries development projects of the Ministry of Industry and Information Technology (hereinafter referred to as "MIIT");

  (3) The special project of the central government guiding local scientific and technological development jointly implemented by the Ministry of Science and Technology and the Ministry of Finance (the matching proportion shall be determined according to the actual contract and the level of the funding unit);

  (4) Other projects that have been reviewed and identified by the leading group of Xicheng Park Management Committee.

  2. Beijing municipal projects

  (1) Small and medium-sized enterprises’ technological innovation funds, special projects for promoting small and medium-sized scientific and technological enterprises, scientific and technological plans, major scientific and technological projects, independent innovation projects of scientific and technological research and development institutions, high-tech achievements transformation projects, special projects for promoting scientific and technological services, and special projects for cultural and technological integration by Beijing Municipal Science and Technology Commission and Zhongguancun Science Park Management Committee (hereinafter referred to as "Municipal Science and Technology Commission"); Major high-tech achievement industrialization support fund projects, cutting-edge technology achievement transformation and industrialization projects, subversive technology research and development and achievement transformation projects, cutting-edge technology enterprise fund projects, industrial development fund projects, and young eagle talent enterprise support fund projects;

  (2) Other projects that have been reviewed and identified by the leading group of Xicheng Park Management Committee.

  (2) Supporting standards

  State-level projects shall be matched according to the ratio of 1:1, and Beijing municipal projects shall be matched according to the ratio of 1:0.5. The total amount of supporting funds for a single project shall not exceed 1 million yuan; If the same enterprise applies for multiple projects, the total annual supporting funds shall not exceed 1.5 million yuan.

  (3) Conditions for application

  1. The enterprise is the subject of project declaration and implementation;

  2. The declared project does not belong to fixed assets investment category, transformation category and commercial facilities supporting category;

  3. If the same project is supported by multi-level project funds at the same time, it shall be supported according to the high amount of funds;

  4. If the year of project establishment is inconsistent with the year of receipt of supporting funds, it shall be audited according to the year of receipt of funds;

  5. If the enterprise undertakes the research and development of sub-projects, it shall provide the main task book of the project and the cooperation agreement signed with the lead unit;

  6. The declared amount shall not exceed the self-raised funds of the enterprise; If the research and development expenses of the project are all supported by the national or municipal funds, they will no longer be matched.

  (4) application materials

  1 annual policy cash application and project matching funds summary table;

  2. Obtain the relevant certification materials of national and Beijing municipal special projects and the proof that the funds are in place;

  3 annual financial audit report of the enterprise;

  4. Other materials related to the declaration.

  II. Awards for R&D institutions established by enterprises (Article 2 (2) of Several Provisions)

  (1) Award criteria

  1. The State Key Laboratory and National Technology Innovation Center recognized by the Ministry of Science and Technology, the National Engineering Laboratory, the National Engineering Research Center and the National Industrial Innovation Center recognized by the National Development and Reform Commission (hereinafter referred to as the "National Development and Reform Commission"), and the National Manufacturing Innovation Center recognized by the Ministry of Industry and Information Technology will be awarded a one-time award of 1 million yuan;

  2. The National Enterprise Technology Center recognized by the National Development and Reform Commission, the National Industrial Design Center recognized by the Ministry of Industry and Information Technology, the Beijing Key Laboratory recognized by the Municipal Science and Technology Commission and Zhongguancun Management Committee, the Beijing Engineering Laboratory recognized by beijing municipal commission of development and reform (hereinafter referred to as the Municipal Development and Reform Commission), the Beijing Engineering Research Center, and the Beijing Industrial Innovation Center recognized by the Beijing Economic and Information Bureau (hereinafter referred to as the Municipal Economic and Information Bureau) will be given a one-time award of 500,000 yuan;

  3. Enterprise Technology Innovation Center, Beijing Design Innovation Center and Zhongguancun Frontier Technology Innovation Center recognized by the Municipal Science and Technology Commission and Zhongguancun Management Committee, and Beijing High-tech Industrial Design Center recognized by the Municipal Economic and Information Bureau will be given a one-time reward of 200,000 yuan;

  4. Other qualifications that have been recognized by the leading group through the policy of Xicheng Park Management Committee.

  (2) Application conditions

  1. The enterprise is the subject of declaration and construction;

  2. The declared qualification shall be newly acquired within the year when the policy is fulfilled;

  3. If the same institution obtains multiple certifications or multi-level certifications, it will be given a one-time reward in accordance with the highest standards, without cumulative rewards.

  (3) application materials

  1. Application for annual policy fulfillment;

  2. Summary of awards for self-built R&D institutions and introduction of R&D institutions;

  3. The organization has obtained the relevant notices and announcements recognized by the State and Beijing Municipality, a copy of the project approval and a plaque photo.

  Three, the enterprise award ("several provisions" second paragraph (two))

  (1) Award criteria

  1 won the first prize of the National Science and Technology Progress Award and above, the first prize of the National Technological Invention Award and above, and the China Patent Prize to give a one-time award of 1 million yuan;

  2. Won the second prize of the National Science and Technology Progress Award, the second prize of the National Technological Invention Award and the silver prize of the China Patent Award, giving a one-time reward of 500,000 yuan;

  3. Get a one-time reward of 300,000 yuan from the "Little Giant" enterprise and "Unicorn" enterprise specialized by the Ministry of Industry and Information Technology;

  4. Won the China Patent Award for Excellence, the second prize of Beijing Science and Technology Award and above, the special prize of Beijing Invention Patent Award and the first prize to give a one-time reward of 200,000 yuan;

  5. Received a one-time reward of 100,000 yuan from the new "Little Giant" enterprise specializing in Beijing by Beijing Economic and Information Bureau;

  6. Other awards recognized by the leading group for consideration by the policy of Xicheng Park Management Committee.

  (2) Application conditions

  1 to declare the award should be newly obtained within the year when the policy is fulfilled. If the award year is inconsistent with the year when the certificate is issued, the time of the certificate shall prevail;

  2 enterprises in the same year won multiple awards, in accordance with the highest standards to give a one-time award, not cumulative award.

  (3) application materials

  1 annual policy cash application and enterprise award summary table;

  2. Award-winning certificates, notices and other relevant certification materials.

  4. Subsidies for R&D expenses (Article 2 (3) of Several Provisions)

  (1) Application conditions

  1. The annual expenditure intensity of scientific and technological activities is higher than the average level of Xicheng Park;

  2 enterprises in the first two years of the reporting year to continue to increase R&D expenses;

  3. The amount of subsidy is calculated based on the amount of R&D expenses increased in the policy fulfillment year compared with the previous year, and is accounted for according to the proportion of 5%. If the amount is less than 100,000 yuan, no subsidy will be granted, and the maximum subsidy will be 500,000 yuan.

  (2) application materials

  1. Annual policy cash application form and summary table of R&D expense subsidy;

  2. A special audit report on enterprise R&D investment in the first three years of the policy declaration year issued by a third-party professional organization;

  3 other materials related to the declaration.

Article 3 Cultivate innovative leading enterprises

  I incentives for key enterprises to settle in (Article 3 (1) of Several Provisions)

  (1) Award criteria

  "Unicorn", invisible champion, listed enterprise or other enterprises with significant influence or outstanding contribution after evaluation, as well as other key high-tech enterprises that meet the industrial positioning of Xicheng Park, can enjoy a one-time comprehensive contribution award in any natural year within three consecutive years since the industrial and commercial tax registration, and will be awarded a maximum of 10 million yuan after comprehensive evaluation according to the development of the enterprise in that year.

  (2) application materials

  1 annual policy cash application and key enterprise reward summary table;

  2. "Unicorn" enterprises, invisible champion enterprises and listed enterprises must provide relevant qualification certificates;

  3. Brief introduction of the enterprise;

  4. Other materials related to the declaration.

  Two, the national high-tech enterprise award ("several provisions" article third (two))

  (1) Application conditions

  1. If a national high-tech enterprise newly moved to Xicheng District in the policy fulfillment year and is within the validity period, and it is recognized as an enterprise in Xicheng District for the first time in the policy fulfillment year, and it is filed by Zhongguancun high-tech enterprise before the first quarter of the policy declaration year, it will be awarded 300,000 yuan, and the reward funds will be allocated in three years, with an annual allocation of 100,000 yuan;

  2. Enterprises that have obtained the national high-tech enterprise qualification for the first time and then apply for the national high-tech enterprise certificate continuously after the expiration of the validity period can enjoy a one-time reward of 50,000 yuan if they fill in the Annual Report on the Development of High-tech Enterprises on time for three consecutive years within the validity period of the last round of qualification.

  (2) application materials

  1 annual policy cash application and national high-tech enterprise award summary table;

  2. National High-tech Enterprise Certificate (provided by Xicheng Park Management Committee according to the high-tech enterprise identification management network of the Ministry of Science and Technology).

  Three, invention patent subsidies ("several provisions" article third (three))

  (1) Application conditions

  1. The declared international and domestic invention patents shall be newly acquired within the year when the policy is fulfilled;

  2. The reporting enterprise shall be the first applicant for the invention patent, and the invention patent obtained by the transferee shall not be subsidized;

  3. Invention patents in Hong Kong and Macao are supported according to domestic invention patent standards.

  (2) application materials

  1 annual policy cash application and invention patent subsidy summary table;

  2. The authorization certificate obtained.

  Four, technical standards subsidies ("several provisions" article third (four))

  (1) Application conditions

  1. The declared technical standards shall be newly released within the year of policy fulfillment, and the official release time shall be subject to the standard release time announced by the standard announcement;

  2 enterprises must rank in the top five in the drafting unit (except national ministries and universities);

  3. Testing standards and revised standards are not supported; In principle, a series of standards are supported by one standard;

  4. If the same technical standard is jointly formulated by many units (enterprises or institutions) in the park, the parties shall make a declaration after negotiating the allocation plan of the amount of support by themselves;

  5. Industry standards shall be supported after being filed by the National Standards Committee;

  6. The fulfillment of this clause shall be audited by Xicheng District Market Supervision Administration. (Accepting institution: Standardization Department of Xicheng District Market Supervision Administration 66503790)

  (2) application materials

  1 annual policy cash application and technical standard subsidy summary table;

  2 "Zhongguancun Science Park Xicheng Park technical standard subsidy application form";

  3. A copy of the business license of the enterprise and a copy of Zhongguancun high-tech enterprise;

  4 standard official text (original), standard announcement, filing announcement (industry standard) and other relevant certification materials;

  5. Other materials related to the declaration;

  6. This clause shall be declared in a separate bound volume.

Article 4 Support the application of new scenarios of cutting-edge science and technology.

  (1) Application conditions

  1. The enterprise is the main body of project investment or research and development;

  2. The original technology applied in the project should reach the international leading level or fill the gap in the domestic industry, which belongs to the global or national launch and is applied in the administrative area of Xicheng District;

  3. The project construction is completed and put into use, and certain economic or social benefits are formed.

  (2) application materials

  1. Annual policy fulfillment application form and new scenario application project report form;

  2. Brief introduction of the project (including technical originality description, intellectual property rights, talent team, technical equipment, software and hardware infrastructure, application scenarios, etc.);

  3. Project investment final accounts report issued by a third-party professional organization;

  4. Details of various expenditures of the project and copies of invoices;

  5. Photographs of project application scenarios;

  6. Description of the economic benefits or social benefits obtained by the project and relevant certification materials;

  7. Other materials related to the declaration.

Fifth, promote the innovation of incubation carriers to improve quality and efficiency.

  Science and technology enterprise incubation institutions (hereinafter referred to as "incubation institutions") recognized and assessed by the Xicheng Park Management Committee shall be given financial support according to the following standards.

  (A) Support standards

  1. According to the "Zhongguancun Science Park Xichengyuan Science and Technology Enterprise Incubator Identification and Assessment Method" and the annual assessment, the identified Xichengyuan Science and Technology Enterprise Incubator will be given financial support from the aspects of promoting regional economic development and cultivating enterprise effectiveness, and the total annual support for each incubator will not exceed 8 million yuan.

  2. Support incubation institutions to guide enterprises to declare high-tech enterprises. The enterprises that were coached or introduced in that year were rewarded and supported according to the standard of 50,000 yuan for each newly added national high-tech enterprise and 20,000 yuan for each Zhongguancun high-tech enterprise.

  3. Encourage incubators to settle in enterprises and increase R&D investment. More than 90% (inclusive) of high-tech enterprises have R&D investment, and the annual average R&D investment accounts for more than the average R&D investment intensity of the park, and 100,000 yuan will be awarded, and 50,000 yuan will be awarded for every 3% increase, and the total annual award will not exceed 500,000 yuan.

  4. Encourage incubators to strengthen the promotion and protection of intellectual property rights of settled enterprises. For those who have obtained the authorization of domestic invention patents within the year when the enterprise policy is fulfilled, each item will be awarded to the incubator 1000 yuan; If an enterprise applies for an international invention patent through the Patent Cooperation Treaty (PCT for short) or the Paris Convention within the year when the enterprise policy is fulfilled, the incubator will be given a reward of 2,000 yuan for each item, and the application for a single patent in six countries will be rewarded at most. The total annual reward shall not exceed 500,000 yuan.

  5. Encourage incubators to cultivate and introduce high-tech enterprises such as listed enterprises, unicorn enterprises and invisible champions, and reward each new one according to the standard of 500,000 yuan.

  6. Support incubation institutions to strengthen their own construction. The state-level and Beijing-level science and technology business incubators newly recognized in the year of policy fulfillment will be given a one-time reward of 500,000 yuan and 200,000 yuan respectively.

  (2) application materials

  1. An application for the annual support fund of the incubator;

  2. Annual work summary of incubation institutions;

  3 incubator annual support fund application summary table and related certification materials;

  4. A summary of the annual presence of incubation institutions in enterprises and relevant certification materials.

Article 6 Enhance the brand influence of characteristic industries

  I. Matching of special funds for publishing design (Article 6 (1) of Several Provisions)

  (1) Category of supporting projects

  1. Publishing special projects

  (1) National cultural industry development project, national cultural innovation project, national cultural science and technology promotion plan, national publishing fund, "Motive Force" China original animation publishing support plan, and China national original online game publishing project;

  (2) Various special funds of Beijing Press, Publication, Radio, Film and Television Bureau;

  (3) Other projects that have been considered by the leading group of Xicheng Park Management Committee.

  2. Design projects

  (1) Beijing Industrial Design Promotion Project and Capital Design Promotion Plan of the Municipal Science and Technology Commission and Zhongguancun Management Committee;

  (2) Other projects that have been considered by the leading group of Xicheng Park Management Committee.

  (2) Supporting standards

  Give matching funds support according to the ratio of 1:0.5 of the funds obtained; If the same enterprise applies for multiple projects, the total annual supporting funds shall not exceed 1 million yuan.

  (3) Conditions for application

  1. The enterprise is the subject of project declaration and implementation;

  2. Enterprises settled in the publishing park can declare special funds for publishing;

  3. If the same project is supported by multi-level project funds at the same time, it shall be supported according to the high amount of funds;

  4. If the year of project establishment is inconsistent with the year of receipt of supporting funds, it shall be audited according to the year of receipt of funds;

  5. If the enterprise undertakes the research and development of sub-projects, it shall provide the main task book of the project and the cooperation agreement signed with the lead unit;

  6. The declared amount shall not exceed the self-raised funds of the enterprise; If the expenses are all supported by national or municipal funds, they will not be matched.

  (4) application materials

  1. Annual policy cash application form and summary table of supporting funds for publishing and design projects;

  2. Obtain the relevant certification materials of national and Beijing municipal special projects and the proof that the funds are in place;

  3 annual financial audit report of the enterprise;

  4. Other materials related to the declaration.

  Two, publishing design awards ("several provisions" article sixth (two))

  (1) Award criteria

  1. Publishing awards

  (1) Won the "Five One Projects" Award and the "World’s Most Beautiful Book Award" for spiritual civilization construction in Publicity Department of the Communist Party of China, giving a one-time award of 1 million yuan;

  (2) Won the "China Publishing Government Award", "Three Hundred Original Publishing Projects" and "China Excellent Publications Award", giving a one-time reward of 500,000 yuan;

  (3) Won the Tao Fen Publishing Award, Mao Dun Literature Award, Lu Xun Literature Award and Bing Xin Literature Award with a one-time reward of 200,000 yuan;

  (4) Won the "50 Popular Books", "Wenjin Book Award", "National Excellent Children’s Literature Award" and "Animation Award of China Culture and Art Government Award", as well as being selected into the "Double Hundred Books Publishing Project of Socialist Core Value System Construction" and "National Animation Quality Project" and given a one-time award of 100,000 yuan;

  (5) Other awards shall be implemented after being reviewed by the policy cash leading group of Xicheng Park Management Committee.

  2. Design awards

  (1) A one-time award of 200,000 yuan was given to the winner of the German Red Dot Award, the German IF Award and the American IDEA Award;

  (2) A one-time award of 100,000 yuan was given to the Red Dot Award and Red Dot Star Award in Germany, IF Design Award in Germany, Silver Award in American IDEA Award, Outstanding Industrial Design Award in China, and Red Star Award (silver award and above) in China for innovative design;

  (3) Other awards shall be implemented after being reviewed by the policy cash leading group of Xicheng Park Management Committee.

  (2) Application conditions

  1. The enterprise is the main body of planning, publishing and distributing works;

  2. The above awards do not include individual awards and nomination awards;

  3. Enterprises settled in the publishing park can declare publishing awards;

  4. The declared awards should be newly obtained in the year when the policy is fulfilled;

  5. If an enterprise has won multiple awards in the same year, it will be given a one-time award in accordance with the highest standards, and there will be no cumulative award.

  (3) application materials

  1. Annual policy cash application form and summary table of awards for publication and design;

  2. Award-winning certificates, notices and other relevant certification materials.

  III. Subsidies for copyright development (Article 6 (3) of Several Provisions)

  (1) Application conditions

  1. The enterprise is the main body of planning, publishing, distributing or investing in works, and the main body of submitting and examining film and television and game works;

  2. Enterprises settled in the publishing park can declare this clause;

  3. The declared works should be newly published within the year of policy fulfillment;

  4. For the works for which the copyright fee is paid in the form of sales volume sharing, the payment time for the copyright signing fee of the works by the enterprise may be extended to June 30th of the policy declaration year, and the total time span of subsidy shall not exceed one full year;

  5. Different works developed with the same copyright shall be rewarded according to the highest standards, and there shall be no cumulative rewards;

  6. If an enterprise develops and produces high-quality audio books with its own copyright, it will be supported according to the total investment of product publishing and distribution (copyright signing fee+production fee): if the cost is 100,000 yuan (inclusive)-300,000 yuan, each work will be subsidized by 10,000 yuan; 300,000 yuan (inclusive)-500,000 yuan, each work will be subsidized by 20,000 yuan; More than 500,000 yuan (inclusive), each work will be subsidized by 30,000 yuan;

  7. Enterprises applying for copyright signing fee subsidies need to be confirmed by the publishing platform of the publishing park.

  (2) application materials

  1 annual policy cash application and copyright development subsidy summary table;

  2. Relevant certification materials such as publication, distribution and submission for trial;

  3. Proof materials such as copyright signing contracts, agreements and payment invoices;

  4. Other materials related to the declaration.

  Four, special talent award ("several provisions" article sixth (four))

  (1) Award criteria

  1. A one-time reward of 500,000 yuan will be given to those who are selected as the leading talents in the national press and publication industry, national cultural masters and "four batches" of talents;

  2. Those who are selected into the "Four Groups" talents of Beijing’s propaganda and cultural system and the "Hundred Talents Project" of Beijing’s publishing talents will be given a one-time reward of 200,000 yuan.

  (2) Application conditions

  1. The declared award should be newly obtained in the year when the policy is fulfilled;

  2 enterprises settled in the publishing park can declare the title award of publishing talents;

  3. Talents who have won the title shall, in principle, have worked in park enterprises (reporting enterprises) for three years; If it is less than three years, it will not cash the reward funds temporarily, and then apply for cash after three years;

  4. If the same person has won multiple titles, he will be rewarded or make up the difference according to the highest single standard;

  5. The reporting subject of this clause is the enterprise where the qualified personnel are located.

  (3) application materials

  1 annual policy cash application and special talent award summary table;

  2. An application signed by the talent himself and stamped with the official seal of the enterprise;

  3. A copy of the ID card signed by the talent himself;

  4. Certification materials for obtaining the title of talent;

  5. Personal tax records of Beijing in the first two years of talents;

  6. The social security payment certificate of the enterprise where the talent is located in the first two years;

  7. A copy of the labor contract signed by the talent and the enterprise for not less than three years;

  8. Other materials related to the declaration.

  V. Special Policy Support for Digital Economy (Paragraph (5) of Article 6 of Several Provisions)

  In accordance with the "Several Provisions on Accelerating the Development of Digital Economy in Xicheng District of Beijing (Trial)" (Westbound Regulation [2020] No.1).

  (Accepting institution: Beijing Xicheng District Bureau of Science, Technology and Information Technology 83976217)

Article 7 Optimize services in technology and finance.

  I. Loan discount (Article 7 (1) of Several Provisions)

  (1) Application conditions

  1. Enterprises are the main body of loans, and personal loans are not supported;

  2. The actual term of the loan is not less than three months and not more than twenty-four months;

  3. The principal and interest of the loan should be completed before December 31st of the policy fulfillment year. Loans that have not completed the repayment of principal and interest will be included in the next year to give support;

  4. If the loan is overdue due to the enterprise’s own reasons, no discount will be given; If the enterprise loan is compensated, it will no longer enjoy the support of loan discount within three years.

  (2) application materials

  1 annual policy cash application and loan discount subsidy summary table;

  2. A copy of the loan contract signed between the enterprise and the bank and the loan certificate; It is the first time for an enterprise to obtain a loan, and it is also necessary to provide relevant certificates for the first loan;

  3. Copies of relevant bills for repayment of principal and interest of enterprise loans;

  4. Other materials related to the declaration.

  II. Special Policy Support for Listing (Article 7 (3) of Several Provisions)

  It is implemented in accordance with the Measures of Beijing Xicheng District for Encouraging and Supporting Enterprises to Go Public (Westbound Regulation [2018] No.4).

  (Accepting institution: Beijing Financial Street Service Bureau 66025302)

Article 8 Encourage innovative and entrepreneurial talents.

  I. Title Award for Innovative and Entrepreneurial Talents (Article 8 (1) of Several Provisions)

  (1) Award criteria

  1 selected "national special support plan for high-level talents" (hereinafter referred to as "national special support plan") outstanding talents with the same category of national talents, giving a one-time reward of 1 million yuan;

  2 selected "national special support plan" leading talents, "Zhongguancun high-end leading talents" equivalent category of municipal talents, giving a one-time reward of 500 thousand yuan;

  3. A one-time reward of 300,000 yuan will be given to those who are selected as top-notch young talents in the National "Hundred Million Talents Project" and "National Special Support Program", outstanding talents or leading talents in the Beijing High-level Talents Innovation and Entrepreneurship Support Program (hereinafter referred to as the "Hi-Tech Plan"), "Science and Technology Beijing Top 100 Talents Training Project" and "Capital Outstanding Talents Award";

  4. Those who are selected as Beijing scholars, young Beijing scholars, "outstanding scientific, technical and management talents in Beijing", outstanding young talents in Beijing, and top-notch young talents in Beijing’s "Hundred Million Talents Project" and "Innovation Plan" will be given a one-time reward of 100,000 yuan.

  (2) Application conditions

  1. The title of talent should be newly acquired in the year of policy fulfillment;

  2. Talents who have won the title shall, in principle, have worked in park enterprises (reporting enterprises) for three years; If it is less than three years, it will not cash the reward funds temporarily, and then apply for cash after three years;

  3. If the same person has won multiple titles, he will be rewarded or make up the difference according to the highest single standard;

  4. The reporting subject of this clause is the enterprise where the qualified personnel are located.

  (3) application materials

  1 annual policy cash application and innovation and entrepreneurship talent reward summary table;

  2. An application signed by the talent himself and stamped with the official seal of the enterprise;

  3. A copy of the ID card signed by the talent himself;

  4. Certification materials for obtaining the title of talent;

  5. Personal tax records of Beijing in the first two years of talents;

  6. The social security payment certificate of the enterprise where the talent is located in the first two years;

  7. A copy of the labor contract signed by the talent and the enterprise for not less than three years;

  8. Other materials related to the declaration.

  Two, talent housing subsidies ("several provisions" article eighth (two))

  (1) Application conditions

  1. If the annual comprehensive contribution of the enterprise policy reaches 2 million yuan (inclusive), this clause can be declared;

  2. Enterprises must rent housing for talents and pay the rent within the year when the policy is fulfilled; Subsidies will be given according to 50% of the actual payment amount, with a maximum subsidy of 300,000 yuan for each enterprise;

  3. The rental housing object should be the senior management personnel and core technical backbone personnel of the enterprise;

  4. Talent apartments provided by Xicheng District Government do not enjoy the support of this clause.

  (2) application materials

  1 annual policy cash application and talent housing subsidy summary table;

  2. The rental contract, a copy of the rental invoice and the proof of the actual payment of the rent transfer (the complete internal examination and approval procedures must be provided for the rental in the form of enterprise reimbursement after individual leasing);

  3. Brief introduction of the actual residents of the enterprise talent housing, a copy of the ID card signed by me, the labor contract, the annual social security payment certificate and the personal tax payment record of Beijing;

  4. Other materials related to the declaration.

Article 9 Promote international exchanges and cooperation.

  I. Supporting international exchange and cooperation projects (Article 9 (1) of Several Provisions)

  (1) Category of supporting projects

  Various international exchange and cooperation projects, international development projects and "going out" projects initiated by the Ministry of Science and Technology, the Ministry of Industry and Information Technology, the Municipal Science and Technology Commission, the Zhongguancun Management Committee, the Municipal Bureau of Economic and Information, and the Municipal Bureau of Press, Publication, Radio, Film and Television and supported by special funds; Zhongguancun International Innovation Resources Support Fund Project.

  (2) Application conditions

  1. The enterprise is the subject of project declaration and implementation;

  2. The declared project does not belong to fixed assets investment category, transformation category and commercial facilities supporting category;

  3. If the same project is supported by multi-level project funds at the same time, it shall be supported according to the high amount of funds;

  4. If the year of project establishment is inconsistent with the year of receipt of supporting funds, it shall be audited according to the year of receipt of funds;

  5. If the enterprise undertakes the research and development of sub-projects, it shall provide the main task book of the project and the cooperation agreement signed with the lead unit;

  6. The declared amount shall not exceed the self-raised funds of the enterprise; If the expenses are all supported by the national or municipal funds, they will no longer be supported.

  (3) application materials

  1. Annual policy fulfillment application form and summary table of matching funds for international exchange and cooperation projects;

  2. Obtain the relevant certification materials of national and Beijing municipal special projects and the proof that the funds are in place;

  3 annual financial audit report of the enterprise;

  4. Other materials related to the declaration.

  Two, multinational institutions to support special policies ("several provisions" article ninth (two))

  In accordance with the relevant special policies issued by Xicheng District Government.

Article 10 Supplementary Provisions

  I. Work flow

  (1) The Xicheng Park Management Committee issues an annual policy declaration notice on the website of Xicheng District Government and WeChat WeChat official account, and enterprises declare various support clauses on Zhongguancun Xicheng Park’s independent innovation declaration system and upload various policy application materials;

  (two) after the first trial, the enterprise shall submit the annual policy paper application materials to the Xicheng Park Management Committee within the prescribed time limit for acceptance, and it will not be accepted within the time limit;

  (3) The declared projects with complete materials shall be considered step by step by organizing the joint deliberation of relevant departments, the deliberation of directors and working committees of Xicheng Park Management Committee, the special meeting of Xicheng District People’s Government, and the deliberation of the Standing Committee of the District Committee;

  (four) the results of the examination and approval shall be publicized on the website of Xicheng District Government for 5 working days, and those that fail to pass the examination will not be notified separately;

  (5) Allocating funds according to the results of deliberation and publicity;

  Second, the relevant requirements

  (1) Enterprises that have obtained the support of policy funds shall conduct accounting treatment according to the relevant national accounting system, separately account for the special funds, use them for special purposes, accept the supervision, inspection and audit of relevant district departments, and actively cooperate with the Xicheng Park Management Committee to carry out relevant work.

  (2) If an enterprise applies for other policies of Xicheng District Government for the same project and the same matter at the same time, it shall be supported according to the principle of preferential treatment; If you have obtained other policy funds of the same type in Xicheng District when applying for this provision, you will not repeat the support.

  (three) to cancel the policy qualification of enterprises that provide untrue materials, and the undistributed support funds will no longer be allocated, and the allocated support funds will be recovered, and they may not apply again within two years; If the circumstances are particularly serious, they shall be handed over to judicial organs for handling.

  (four) before the actual disbursement of support funds, if it is found that the enterprise has illegal operations and is included in the list of untrustworthy people, it will no longer be supported.

  (five) the total amount of funds obtained from all the terms of the enterprise’s annual application (except Article 3 (1) (2) and Article 5) shall not exceed 50% of the comprehensive contribution of the enterprise’s annual policy.

  Iii. Requirements for application materials

  1. The application for annual policy fulfillment and the summary table of various terms in paper materials (automatically generated by the online declaration system) shall be stamped with the official seal;

  2. Paper materials are in duplicate, formally bound into a book, and the cover and riding seam are stamped with official seals. The summary table and certification materials required for each clause are separated in the order listed in the application. Among them, the application materials for technical standard subsidies in Article 3 (4) are bound separately.

  These Rules shall be implemented as of the date of promulgation. The Detailed Rules for the Implementation of Several Provisions of Xicheng District of Beijing on Supporting the Independent Innovation of Zhongguancun Science Park Xicheng Park (for Trial Implementation) (Xike Guanfa [2023] No.1) shall be abolished at the same time. Support standards from 2022 onwards shall be implemented in accordance with these detailed rules.

  Note: 1. Year of policy fulfillment: the year when enterprises get support to carry out scientific and technological innovation.

    2. Policy declaration year: the year when the organization conducts policy declaration.

Cross-provincial medical treatment in different places, easy online filing! (with detailed operation method)

The National Medical Insurance Bureau and the Ministry of Finance jointly issued the Notice on Further Improving the Direct Settlement of Medical Treatment in Different Provinces of Basic Medical Insurance. The "Notice" clarifies that insured persons who live in different provinces for a long time or temporarily go out for medical treatment in different provinces can enjoy direct settlement services for medical treatment in different provinces after filing for medical treatment in different places. The "Notice" pointed out that before the end of 2025, the inter-provincial direct settlement rate of hospitalization expenses will be increased to over 70%, and medical insurance reimbursement can be basically handled across provinces online and offline.

From January 1, 2023, the direct settlement of medical treatment across provinces was officially implemented! Which groups are applicable? How to file? How to settle accounts? Let’s have a look!

01
What are the specific applications?What about the crowd?

Long-term residents in different provinces include retirees resettled in different places, long-term residents in different places, permanent staff in different places and other people who have worked, lived and lived outside the insured provinces, autonomous regions and municipalities directly under the central government for a long time;

Inter-provincial temporary medical personnel include those who have been referred for medical treatment in different places, emergency rescue personnel in different places due to work, tourism and other reasons, and other inter-provincial temporary medical personnel.

02
How to handle cross-provincial and different placesWhat about medical record?

Scan the sunflower code below,
The State Council client applet
[Inter-provincial medical record in different places]
To help you!

Step 1: Scan the code to enter the applet, and click [Start Filing].

Click [Start Filing] to enter the "Off-site Filing" page, where the insured can inquire about the opening of the overall planning area and the opening of designated medical institutions (inpatient, outpatient, outpatient with chronic diseases).

Step 2: Click [Application for Record of Medical Treatment in Different Places] and select the record type.

According to the actual situation, the insured chooses the insured place, medical place, insurance type and filing type.

Step 3: Read the filing notice and submit the filing materials.

Check the filing information, select the start time of filing application, fill in the contact information, and upload the corresponding filing certification materials according to the different categories of filing personnel, such as resident ID card, referral and transfer certification materials, residence permit, work contract, etc.

Tip:

According to the Notice on Further Improving the Direct Settlement of Medical Treatment in Different Provinces of Basic Medical Insurance,

Emergency personnel in different places are deemed to have been filed, and no additional filing materials are required.

Medical records in different places are allowed to be reissued. If the insured person goes through the medical record in different places before the inter-provincial discharge settlement, the designated medical institution connected to the medical place shall handle the inter-provincial direct settlement of medical expenses for the insured person. If the insured person who goes to different provinces for medical treatment goes through the filing formalities according to the regulations after being discharged from hospital at his own expense, he can apply for manual reimbursement of medical insurance according to the regulations of the insured place.

Long-term residents in different provinces shall register for the record, and the record shall be valid for a long time; In principle, the validity period of the inter-provincial temporary medical personnel is not less than 6 months. During the validity period, they can see a doctor many times in the medical place and enjoy the direct settlement service of inter-provincial medical treatment in different places.

Step 4: Check the filing progress.

Go back to the home page and click Progress Query to query the filing status with one click.

03
After the record is successful, you canSelected points, certified medical treatment.

Selected point:

According to the demand, select the designated medical institutions/retail pharmacies networked in different places.

Here’s the guide → Designated hospitals and pharmacies for medical insurance, one-click query →

Holding a code card for medical treatment:

Insured persons are required to show valid certificates such as medical insurance electronic certificate or social security card when they register in hospital, settle accounts at discharge and settle accounts at outpatient clinics.

Electronic social security card/medical insurance electronic certificate is also effective, and scanning code is available!

Inter-provincial networked designated medical institutions provide reasonable and standardized diagnosis and treatment and direct settlement services for medical expenses for outpatients (emergency) and inpatients who meet the requirements of medical places.

Pay attention to the the State Council client service number.
Send keywords in the dialog box
"medical treatment in different places" and "social security",
You can also get related services quickly!

Beijing CDC recommends # 7 to 14 days before purchasing overseas mail-order items.

Today (April 7) afternoon, Beijing held a press conference on epidemic prevention and control to introduce the epidemic situation and the latest progress in epidemic prevention. A reporter at the scene asked, this round of epidemic has caused infection by overseas mail-order items. How do citizens dispose of the purchased overseas mail-order items? In this regard, Pang Xinghuo, deputy director of the Beijing Center for Disease Control and Prevention and a member of the national novel coronavirus expert group, said that there have been reports of Covid-19 nucleic acid positive in overseas mail, clothes and other articles in many places in China recently. Pang Xinghuo specially reminded the general public and friends that it is not necessary to buy less Haitao during the high-incidence period of foreign epidemics, and be careful to mail-order goods from countries and regions with high-incidence epidemics. If you have purchased goods that are not urgently needed, it is recommended to put them at room temperature for 7-14 days before processing.

Pang Xinghuo said that when receiving overseas mail or articles, you should wear masks and disposable gloves correctly, reduce direct contact, pick up the pieces at a fixed place as much as possible, and realize contactless handover. If you need to sign in person, please keep a safe distance; Dismantle the parts outdoors as far as possible, and go home without outer packaging, and treat them according to the classification of domestic garbage. If you need to take them home, you can spray or wipe the surface of mail and express delivery with chlorine-containing disinfectant or 75% alcohol to ensure that each side is completely wet, ensure all-round disinfection, and at the same time do a good job in disinfection of unpacking and transshipment tools; Mail-order items can be disinfected by disinfectants and thermal disinfection, or stored for a period of time before use; After handling mail and express delivery, you should take off gloves in time, change masks, carefully clean your hands or disinfect them, and avoid touching your mouth, eyes and nose with unclean hands.

About screening for diseases during pregnancy


 

For all diseases, whether pregnant or non-pregnant, the first strategies recommended by doctors are: early prediction, early detection, early prevention and early intervention. This is a common practice in health management, health promotion, disease prevention and disease control.

This unisex practice in Xian Yi, old and young, is best implemented in obstetrics, which is universal.Pregnancy check-up mode.

The mode of prenatal check-up during pregnancy originated in Britain. As early as 1929, the British Ministry of Health issued a memorandum recommending pregnant women to have regular prenatal check-ups. This systematic management mode of prenatal check-up was quickly accepted and popularized all over the world.

In the last century, this measure made a great contribution to the remarkable reduction of maternal mortality and perinatal mortality rate all over the world.

The main purpose of prenatal examination is screening for diseases during pregnancy.For those relatively common diseases that may have adverse effects on mothers and fetuses, screening is conducted in order to find risks, make early prediction, early prevention and intervention.

Screening for diseases during pregnancy is aimed at normal people.It is all pregnant women, not a few, who want to screen out people with problems in the normal population.

So don’t always question why everything is normal when you are pregnant. The doctor still has to prescribe all kinds of laboratory tests for you. You should be happy to find out that there is no problem. Don’t think it’s a waste of money. Do you want every penny to be spent, and every laboratory test can find out the problem?


 

(Source: Giphy)

If it is a high-risk population, screening is generally not needed, and diagnostic examination can be carried out directly.

Compared with screening, diagnostic examination methods are usually more complicated, more expensive and more likely to be invasive.

As for which diseases need screening, which diseases don’t need screening and which screening method to use, it needs comprehensive consideration.

Screening needs to balance screening efficiency, sensitivity, specificity, cost-benefit analysis, how much money to spend and how many people to screen before a patient can be diagnosed.

Therefore, you will see that different countries and regions will have different recommendations for the check-up items during the whole pregnancy. Some check-up items are more, while others are less, which is mainly a cost-effective choice.

The prenatal check-up during pregnancy is a model and pioneer of systematic and comprehensive disease screening for the whole population in the history of modern medicine. Many non-pregnant people learn the strategies of disease screening from the prenatal check-up.

At present, during the check-up, the commonly used screening for diseases during pregnancy includes:down syndrome screening,B-ultrasound screening for macromalformation,Preeclampsia screening,Premature birth screening,screening for gestational diabetes mellitus,Thyroid disease screening,Screening for sexually transmitted diseases,GBS screeningWait, I will take the most common Down’s screening as an example to make an introduction for everyone.

In the whole population, the incidence of Down syndrome is about 1/800-1,000. In order to improve the efficiency and reduce the risk, we usually adopt the combination of screening and invasive diagnosis.

That is to say,For a high-risk minorityWe do invasive amniocentesis and karyotype analysis directly.

For normal peopleFirst, we screen the mother’s peripheral blood. For pregnant women with high risk of screening, we do invasive amniocentesis and karyotype analysis.

There are two main screening methods now, one is the traditional and classic screening of maternal peripheral blood biochemical indicators, which is also called ".down syndrome screening",and the other is advanced screening, that is, non-invasive examination of fetal free DNA in maternal peripheral blood, also referred to as".noninvasive”。

Compared with the traditional "Down’s screening", the price of "non-invasive" will be higher, but the detection rate of Down’s syndrome will be higher, and the false positive rate and false negative rate will be lower, which can reduce more unnecessary amniocentesis.

The results of traditional "Down’s screening" will be divided into three categories: high, medium and low risk, or high and low risk. The cut-off value of high risk is usually set at 1/250, and the high risk will be recommended for amniocentesis.

Therefore, if you want to do screening, you need to know a lot of terms related to screening and the meaning behind these terms.

The following terms and meanings are related to Down’s Screening:

Background risk:The probability and risk of Down’s syndrome in the normal population is about 1/800-1,000.

Screening risks:When you do "Down’s Screening", the risk value may be low risk or high risk.

Residual risk:Even if the result of Down’s screening is low risk, it doesn’t mean that everything is fine, and there is still a relatively low risk, which is the so-called residual risk.

Invasive diagnostic risk:If it is a high risk, you will be advised to do amniocentesis. The risk of abortion caused by amniocentesis is about 1-2/1000, which is the additional risk brought by invasive diagnosis itself.

Game theory game theory:Doing "Down’s Screening" is actually betting on probability, that is, making a choice between the above probabilities and making a choice.

In the normal population, the incidence of Down syndrome is about 1/800-1,000. You can choose to do "Down screening" or not.

Some people think that this probability is very low, so they decide not to do it, but what if they win the prize?


 

(Source: Giphy)

If the result of "Down’s Screening" is that the risk is 1 in 200, the doctor suggests that you do amniocentesis, and the probability of miscarriage is 1-2 in 1,000, do you do it or not?

Which risk are you more afraid of?

Screening or not screening? Do you need an invasive diagnosis? This is betting on probability.

The correct and reasonable choice principle is to look at the high probability, and to consider the balance between income and risk. It is not only the probability that you gamble, but also whether you are willing and able to accept the consequences of gambling loss.

Gamble if you can afford to lose, even if the risk of 1/100 is not high. If you can’t afford to lose, don’t gamble, even if the risk of 1/1000 is too high, you have to be willing to gamble and lose.

With the continuous progress of technology, more and more diseases can be screened. Even for the same disease, more and more screening methods can be selected, and the screening methods are becoming more and more accurate.

Of course, you are facing more and more choices. Are you ready, students who love to struggle?

9.3 points! The welfare returns in the middle of the night, and I look silly …

I finally got off work-

You look at the crowded subway, sigh and stick it up. When you get home, you can unload your fatigue, open a hit drama and enjoy the rare free time.

This is the spiritual comfort of contemporary migrant workers-binge-watching.

But these spiritual foods are often uneven, especially seasonal dramas, which can be called unfinished professional households:

One season reached its peak, the level declined in two seasons, and the three seasons were beyond recognition …

Is there a season drama that breaks the curse of the rotten end?

There is!

Ten years, it’s as usual-

When the ninth season started, it still got a high score of 9.3. What’s the secret?

NO, "The Lonely Gourmet" not only doesn’t have a secret book to keep it hot, but even the story is very simple. It has been telling the same thing for nine seasons-

One is calledKogoro, head of the wellA grocer (decorated by YUTAKA MATSUSHIGE) looks for delicious food during work breaks.

The story of Goro and food has also become the youth of many people, and every season, some people are willing to come again for hundreds of millions of times.

At the beginning of the ninth season, Wu Shu, who has not seen for a long time, stood at the door of the food store, and his memories popped up instantly.

"Knocked-"

Uncle Wu, who just finished the negotiation, is hungry.

This familiar picture, my DNA also moved …

Uncle Wu found a small shop that fried pork chops, and watched the diners in the shop feasting. Uncle Wu’s greedy worm was completely hooked up.

Not much to say, let’s have one firstFried pork chop with loin meat——

The crispy shell is wrapped in thick pork chops, topped with sauce, and the meat flavor and sauce blend perfectly, which is the top enjoyment of taste buds.

Second mealGolden fishWonderful, the soft fish fully absorbs the sauce, picks up a piece and chews it carefully, and the fresh fragrance of the fish rolls in the mouth, absolutely!

Not only can you learn about Japanese food with Uncle Wu, but you can also see Uncle Wu occasionally.Tasting European food.

This time, Uncle Wu brought us here.Greece.

Greek cuisine is not on the same channel as East Asia in terms of material selection, and it is full of strong European flavor.

Can you imagine that grape leaves can also be made into food? !

Uncle Wu still played his gift of eating ~

Pour lemon juice, and the acidity will be enhanced, which is another flavor.

In addition to foreign food, The Lonely Gourmet also has an essential link-Chinese cooking.

This time, Uncle Wu ateGuizhou cuisineGuizhou cuisine is spicy and delicious, which is quite different from that in Sichuan and Chongqing.

This dish of Sichuan style pork is rich in color and fragrance, and the fat but not greasy meat slices are mixed with the fragrance brought by pepper, which is spicy and cool!

How can there be no lobster sauce hot pot in Guizhou restaurant?

Amorphophallus konjac, baby cabbage, Flammulina velutipes, potato chips, thousand pages of tofu …

There is also a hot pot standard-mutton.

The steaming picture is matched with Wu Shu’s inner monologue, and the smell of hot pot seems to have overflowed the screen ~

Uncle Wu’s monologue when eating hot pot is a deep understanding of hot pot.

The spicy and refreshing feeling stimulates the taste buds, and even if you sweat, you won’t give up the delicious taste. This feeling can be accurately described only by "enter the dragon", which is not bad.

The subtle metaphor makes the food come alive instantly.Every psychological activity is a prelude to the strategy of food, and it is the pure attitude towards food that makes The Lonely Gourmet become a drama for many people.

And this thing, once done, is ten years.

"Lonely Gourmet" was launched in 2012, and it has been ten years since then. Uncle Wu has also moved from middle age to old age.

This foodie uncle who is rich in inner drama and likes to gossip is the youth of many people. Seeing him eating with relish will ease his gloomy mood.

We are used to "I’m so hungry!" after Uncle Wu’s discussion. ;

I also know that after he enters the store, he will make a choice phobia in the face of dazzling food;

When enjoying food, he can always find an accurate description of the angle and let the audience be there.

It seems that everything is used to it, but in fact it can’t be separated from the actors’ efforts.

YUTAKA MATSUSHIGE won’t eat for a whole day before each shooting, and only in this way will he feel ecstatic when shooting.

This season’s filming is particularly difficult. During the epidemic, YUTAKA MATSUSHIGE wore a mask and shuttled through the food store, and also spoke frankly about the impact of the epidemic on the catering industry.

In addition, there is no ups and downs in the whole drama, and no characters have cooperated with YUTAKA MATSUSHIGE for a long time. The drama is supported by the strength of the actors.

In the play, Uncle Wu is looking for food alone. Off-stage, it was YUTAKA MATSUSHIGE who made a one-man play for ten years.

Uncle Wu and YUTAKA MATSUSHIGE have a certain degree of overlap, and at some point, they are all lonely.

Although the characters and plot of Lonely Gourmet are slightly thin and the shooting environment of the ninth season is not ideal, itStill holding the purity of food, coming to us with a cure..

The Lonely Gourmet lasted for many years and gained a large number of loyal audiences.

There is nothing but-healing in resonance.

Uncle Wu is actually a microcosm of modern people.

The people behind him are more in the cubicle, in the assembly line and on the way to work.

Modern life divides everyone into independent individuals, and the more people travel alone in the stream of people.

Sometimes it seems like calling friends, but the deep loneliness is lingering, which is a common fault of modern people.

Lonely is not a gourmet, but you and I who hurried home after the lights went out.

The reality is a little sad, but the appearance of Uncle Wu saved the sorrow.

"Lonely Gourmet" perfectly hides the tired side of Uncle Wu under the delicious food, seemingly enjoying the delicious food, but actually curing loneliness.

In the only free time, I throw away all my troubles and eat without distractions, which not only makes my stomach full but also decompresses.

just asThe beginning of each episode——

The pictures in this article are from the Internet. If there is any infringement, please contact and delete.


Being separated from the world during food time, gaining temporary spiritual freedom and eating well are the lowest cost sources of happiness.

So, did you have a good meal today?

Regenerative Medicine Breakthrough China Scientists Induce Human totipotent Stem Cells.

  Recently, researchers from China Academy of Sciences, Shenzhen Huada Institute of Life Sciences and other institutions have cultivated human pluripotent stem cells in a state similar to that of fertilized eggs developing for three days through somatic cell induction. This is the "youngest" human cell cultured in vitro in the world at present, and it is another subversive breakthrough in the field of regenerative medicine after scientists successfully induced human pluripotent stem cells. Related research results were published in the international academic journal Nature in the early morning of March 22nd, Beijing time.

  It is understood that researchers have developed a non-transgenic, fast and controllable "cocktail" cell reprogramming method, which can transform human pluripotent stem cells into totipotent 8-cell embryonic-like cells, that is, totipotent stem cells equivalent to the three-day development of fertilized eggs. This achievement will help to realize the in vitro regeneration of human organs in the future, and it is of great significance to solve the problems of organ shortage, allograft and xenotransplantation rejection.

  In 2012, the Nobel Prize in Physiology or Medicine was awarded to shinya yamanaka, a Japanese scientist who successfully induced mature somatic cells into pluripotent stem cells in blastocyst stage. The cells in human blastocyst stage are fertilized eggs developing 5-mdash; In the state of 6 days, its ability to further develop is limited.

  However, this study has made a big step forward in this field, and for the first time, embryonic cells with fertilized eggs divided for only 3 days were obtained. In the early stage of fertilized egg development, great changes have taken place every day, and it is these 2-mdash; In 3 days, scientists obtained human 8-cell embryonic-like totipotent stem cells through in vitro induction for the first time. This is the "youngest" human cell induced in vitro so far, and it has very strong development potential. This study will also help to unlock the key to the early development of human embryos.

  According to reports, these totipotent 8-cell embryonic-like cells reconstructed the embryonic state of fertilized eggs after only three times of division. Compared with pluripotent stem cells in the past, these cells can differentiate into placental tissues and may develop into more mature body tissues.

  "This progress is also a model of the combination of regenerative medicine and single cell sequencing technology." Dr. Liu Longqi from Shenzhen Huada Institute of Life Sciences, one of the authors of the paper, said, "The efficient identification and mechanism analysis of cells or tissues obtained by stem cell technology in vitro or in vivo will greatly accelerate the development of regenerative medicine."

  This is the first time that researchers have "transformed" human pluripotent stem cells into pluripotent embryonic cells in a real sense, so that people can reverse the "adult" version of cells into "infant" versions with more possibilities. At the same time, because the totipotent cells obtained this time are closer to the original state of early embryos, if they are used in regenerative medicine, the cultivated organs will be closer to the state of real organs, which is more conducive to transplantation.

  This breakthrough is due to the progress of single cell sequencing technology. In the past, researchers may have to process and culture thousands of cells, and the probability of success is less than 10%. Nowadays, based on the single-cell library sequencing platform (DNBelab C4) independently developed by Huada University, combined with the DNBSEQ sequencing technology created by Huada Zhizhi, scientists can conduct multidimensional single-cell analysis with high sensitivity and accuracy, quickly obtain cells with important development potential, and study the development direction of these cells.

  In this study, the research team also classified the induced pluripotent stem cells and injected them into mice for further development, and then used the single cell sequencing technology of Huada to conduct large-scale cell map analysis. Finally, the researchers confirmed that the experimental totipotent stem cells were highly similar to human 8-cell embryonic cells, which proved the totipotency of the cells. This provides a scientific basis for organ culture using patients’ own cells in the future and for organ transplantation and replacement.

  The research was led by China Academy of Sciences and Shenzhen Huada Institute of Life Sciences, with the participation of several research teams including Cambridge University, Jilin University and rajshahi University. This study has passed the ethical review and strictly followed the corresponding laws and regulations and ethical standards.

Notice on printing and distributing the measures for the administration of the selection of excellent construction sites for standardized management of construction safety in Hangzhou.

District, county (city) Construction Bureau, the relevant units directly under the Committee, the construction and supervision enterprises:

In order to further promote the standardization and standardization of safety and civilized construction management of construction projects in our city, and improve the management level of construction sites, according to the Implementation Measures for Excellent Site Evaluation of Standardization Management of Construction Safety in Zhejiang Province by the Provincial Department of Housing and Construction, we have revised the original Management Measures for Standardized Model Sites of Construction Projects in Hangzhou, which are hereby promulgated, please implement them carefully.

Hangzhou Urban and Rural Construction Committee

June 16, 2020

Standardized management of construction safety in Hangzhou cityMeasures for the Administration of Excellent Site Selection

Chapter I General Provisions

Article 1 In order to further improve the management level of safe and civilized construction of construction projects in the whole city and standardize the selection and management of excellent sites for standardized management of safe and civilized construction, these management measures are formulated in accordance with the provisions of People’s Republic of China (PRC) Construction Law, Regulations on Safety Production Management of Construction Projects, Several Opinions of the Ministry of Housing and Urban-Rural Development on Promoting the Development and Reform of Construction Industry, Implementation Measures for Evaluation of Excellent Sites for Standardized Management of Construction Safety Production in Zhejiang Province and other laws, regulations and documents, combined with the actual situation of Hangzhou.

Article 2 These Measures shall apply to newly built, expanded and rebuilt houses, municipal infrastructure projects and urban rail transit projects within this Municipality.

Article 3 The Hangzhou Urban and Rural Construction Committee (hereinafter referred to as the Municipal Construction Committee) shall be responsible for organizing and implementing the selection and management of excellent construction sites for standardized production safety management of construction projects in Hangzhou. City Construction Engineering Quality and Safety Supervision Station, District and County (city) Construction Bureau (or its entrusted supervision and management institutions) (hereinafter collectively referred to as "supervision institutions") are responsible for supervising the project process evaluation and report selection.

Article 4 The selection of excellent municipal standardization sites shall be conducted by combining process evaluation, expert review and jury review. The supervision organization is responsible for the process evaluation and forms the process evaluation opinions; Expert review by the expert group to review the application materials, daily management and evaluation materials of enterprises, and put forward review and evaluation opinions; Jury review by the jury according to the process evaluation opinions, expert group review opinions to review, vote to determine the candidate list of winning projects.

Fifth city standardized excellent site evaluation number of total control, merit selection. The allocation of reporting indicators shall be based on the principle of territoriality where the project is located, and shall be allocated and adjusted according to the following factors:

(a) the scale of the project construction and the completion of the project in that year;

(two) according to the overall level of production safety management, especially the annual production safety situation in each district;

(3) Give due consideration to regional and professional balance.

Chapter II Application Conditions

Article 6 The excellent site of city standardization shall be selected once a year on the basis of voluntary declaration by enterprises and recommendation by supervision institutions. The projects participating in the selection of city standard chemical sites shall have the following scales:

1. Residential groups with a single residential project of more than 4,000 square meters and a construction area of more than 15,000 square meters, and supporting villas of more than 5,000 square meters;

2. For public buildings with a construction area of more than 5,000 square meters, the public construction area of counties (cities) shall not be less than 4,000 square meters. Renovation works of antique buildings of more than 600 square meters or major ancient buildings and garden buildings of national key cultural relics protection units;

3. Installation of industrial equipment with independent devices with a project cost of more than 15 million (including 15 million);

4. The construction cost of general municipal infrastructure projects is more than 15 million (including 15 million), and the construction cost of counties (cities) is more than 10 million (including 10 million);

5. Station, depot, comprehensive base, control center, section, tunnel and elevated unit projects with a cost of 50 million yuan or more in urban rail transit projects; Main track project with a cost of more than 50 million yuan;

6. The construction cost of tunnels, sewage treatment plants, water purification plants, plazas and other construction projects is more than 30 million (including 30 million), and the construction cost of county (city) construction projects is more than 20 million (including 20 million). In the square project, the square civil construction area should be no less than 50% of the total area, and the engineering quantity should be no less than 60% of the total;

7. The project scale does not meet the above requirements, but it has remarkable economic, social and environmental benefits, and has made outstanding achievements in creation.

Article 7 An enterprise that declares an excellent site for city standardization must meet the following conditions:

1 registered construction enterprises in this Municipality or foreign construction enterprises that have entered the construction credit network in Hangzhou, and have corresponding qualifications;

2 enterprises in the administrative area of this Municipality within 1 year without major and above quality and safety accidents;

Eighth to participate in the city standardization excellent site selection site must meet the following conditions:

1 projects completed in the new round of selection cycle;

2 in line with the national capital construction procedures, the main market behavior norms of all parties to the project construction;

3. Has been included in the district, county (city) Construction Bureau and the municipal quality safety supervision station to create a standardized excellent site plan, in line with the relevant national, provincial and municipal construction safety technical standards, specifications and requirements, and the relevant provisions of safe production and civilized construction, and the management of safe production and civilized construction has reached an advanced level;

4. Actively promote the use of new materials, new technologies, safety protection facilities, construction machinery and equipment and green construction measures;

5. Establish grass-roots party organizations at the construction site, and carry out activities such as party building and joint construction with construction administrative departments, regulatory agencies or territorial communities;

6 for the construction safety production liability insurance (or liability insurance with the same nature as the safety liability insurance);

7. Actively implement other work assigned by construction administrative departments at all levels.

Chapter III Establishment of Declaration

Ninth to participate in the city standardization excellent site selection site by the general contractor of the project to declare, the construction permit information exists more than two (including two) contractors, should take a joint declaration.

Professional contracting enterprises that have completed Jian ‘an project account for more than 20% of the project quantity, and construction enterprises in residential quarters (including contiguous houses and public buildings) that account for more than 10% of the project Jian ‘an project quantity can declare as contractors, but the total number shall not exceed three.

Article 10 When applying for a project with excellent standardized site in the city, the enterprise shall include the creation plan in the annual management target of safety production before the start of construction, and formulate the implementation plan for the project with excellent standardized site. Fill in the creation schedule (Table 1) within 30 working days after the project starts, and report it to the supervision institution.

Article 11 The supervision institution shall, within 10 working days after accepting the enterprise’s creation schedule, make a preliminary investigation on the scale and conditions of the declared project, and register those that meet the selection requirements. The construction unit shall fill in the "Receipt Form of Excellent Site Election Card for Standardized Management of Construction Safety in Hangzhou" (see Annex 2), and go to the Municipal Construction Industry Association to receive the plaque of "Excellent Site Election Project for Standardized Management of Construction Safety in Hangzhou" after being confirmed by the seal of the supervision institution, and hang it at the gate of the construction site to accept social supervision. The plaque is made by the Municipal Construction Committee.

Article 12 From the second month after the start of construction and the end of the project completion acceptance, the enterprise shall fill in the Self-assessment Form for Municipal Standardization Excellent Site Inspection (Form for Construction and Supervision Enterprises) (Annex 3) every month, and take photos of different parts of each sub-category reflecting the safe and civilized construction according to the ten sub-categories of the Construction Safety Inspection Standard (JGJ59-2011), and upload them to the platform of Hangzhou Standard Chemical Industry Comprehensive Supervision System (hereinafter referred to as

Thirteenth enterprise application data and dynamic management data of supervision institutions must be uploaded to the system platform. After the selection is started, the supervision institution will review the application materials of excellent standardized construction sites uploaded by enterprises on the system platform, and summarize the projects that have been approved and submitted to the Municipal Construction Committee. The specific application materials on the system platform are as follows:

1. Application Form for Excellent Site of Hangzhou Construction Safety Production Standardization Management (Annex 4);

2. Report the three-stage inspection and evaluation form of the construction site (foundation, main body and decoration) (Annex 5);

3. Inspection record form of supervision institution (Annex 6);

4. Introduction of the reporting enterprise on the creation of excellent site for city standardization;

5. If there are contractors, provide the certification materials of contractors;

6. Records of project completion acceptance;

7. Other supporting materials that need to be provided;

8. Pictures and images of the project construction site.

Chapter IV Dynamic Management

Article 14 The supervisory institution shall, according to the establishment plan of the declared enterprise and on the basis of daily supervision and management, randomly check the basic stage, main construction stage and decoration stage at least twice each, and fill in the Inspection Record Form of Supervisory Institutions in time.

Fifteenth city standardized excellent site listing, delisting dynamic supervision and management system. In the process of construction, any of the following circumstances shall be delisted and its qualification for creation shall be cancelled:

1. General and above safety production accidents occur;

2 by the construction administrative department to make general administrative punishment;

3. Accidents of production safety responsibility such as overturning of hoisting machinery, collapse of foundation pit, collapse of formwork support system, fire, etc. occur, although no casualties are caused, but the social impact is bad;

4. Other events that have caused great negative social impact occur.

Sixteenth in the construction process, one of the following situations will be given a yellow card warning; In the construction period of the project, those who have been warned twice by yellow cards will be delisted and disqualified:

1. The use of construction machinery, equipment, products and processes prohibited by the state;

2. Having been given two simple administrative punishments by the administrative department of construction within one year;

3 due to arrears of wages of migrant workers, construction noise, dust pollution, etc., it is the responsibility to complain and report, resulting in adverse social effects.

4. The site management of the construction workers is not in place and is completely shut down by the competent construction department.

Article 17 The construction engineering safety supervision institution shall specify the telephone number of complaints, accept the complaints and reports of violations of laws and regulations in the construction site with excellent standardization, and verify them in time. Anyone who meets the requirements in Articles 15 and 16 of these Measures shall be given a yellow card warning or delisted; Delisting projects shall not be declared to be excellent construction sites of city standardization, and at the same time, differentiated management shall be implemented and supervision shall be strengthened.

Chapter V Selection Methods and Procedures

Article 18 The Municipal Construction Committee established the Hangzhou Excellent Site Selection Committee (hereinafter referred to as the jury) for standardized management of construction safety in construction projects. The jury has an office (located in the Engineering Department of the Municipal Construction Committee). The office of the jury is responsible for the daily work of the selection of excellent construction sites for standardization.

Nineteenth establish a system platform, form an electronic file for the management of safe and civilized construction of declared projects, and fairly and objectively display the dynamic management process of safe and civilized construction of declared projects.

Article 20 The project score is based on the percentage system, which consists of the process evaluation score of the supervision institution (accounting for 50 points) and the expert evaluation score (accounting for 50 points), in which the process evaluation score of the supervision institution is converted by the average score on site; The expert evaluation score is a comprehensive evaluation score of the establishment and management of the enterprise standard chemical industry, the monthly self-evaluation form of the enterprise and the photos of the construction site in the application materials.

If the sum of the two scores exceeds 80 points, they are eligible to participate in the voting session of the Municipal Standardization Excellent Site Jury.

Twenty-first the following circumstances can be based on the evaluation score of the project, and the project can be added or subtracted:

1. Extra points:

(1) those who actively organize and participate in the party building activities in the industry and win the commendation honor of the party building in the industry or hold the on-the-spot meeting of party building, according to the district (county), city, province and ministerial level, can add 1, 2, 3 and 5 points respectively;

(2) Organize the on-site meetings of quality, safety and civilized construction at district (county), city, province and ministerial level, and add 2, 4, 6 and 10 points respectively;

(3) District (county), city, province, the State Council construction administrative departments informed in recognition, respectively, add 1, 2, 3, 5 points.

If you add points to the same item, it will be high or low, and you will not repeat the points.

2. Subtraction:

(1) informed criticism, the administrative department in charge of construction in the district (county), city, province and the State Council, will be deducted 2 points, 4 points, 6 points and 10 points respectively. If the same item is deducted, it will be high or low, and it will not be repeated.

(2) If a summary administrative penalty is imposed, 2 points will be deducted each time;

(3) Failing to hang the plaque of "Excellent Site Participation Project of Hangzhou Construction Safety Production Standardization Management" as required, 1 point will be deducted each time.

Twenty-second comprehensive project score is determined, the Municipal Construction Committee organized a jury meeting. The members of the jury shall be composed of relevant offices of the Municipal Construction Committee, directly affiliated units and district and county (city) construction bureaus, and the members of the jury and evaluation experts shall not repeat.

According to the project evaluation, process evaluation and expert evaluation opinions, and combined with the evaluation, the members of the jury selected the winning project by secret ballot. Vote for the number of participating projects that reach more than two-thirds (including two-thirds) of the number of judges, and obtain excellent construction sites for city standardization. Voted to reach more than half of the number of judges (including half), less than two-thirds of the participating projects, won the honorary title of city praise project.

Twenty-third winning projects shall be publicized on Hangzhou Construction Online, and the publicity period shall be 7 working days, subject to social supervision. If there is no objection at the expiration of the publicity period, a document will be issued to announce the selection results.

Chapter VI Selection Discipline and Reward

Twenty-fourth reporting enterprises should adhere to the principle of seeking truth from facts, and the application materials should not be falsified. Violators will be disqualified from reporting and participating. When accepting the inspection, it is not allowed to stop work and wait for inspection, and it is not allowed to entertain and give gifts. Once found and verified, it will be criticized according to the seriousness of the case until the qualification for declaration and participation is cancelled.

Article 25 The inspectors, examiners and assessors should handle affairs impartially, strictly observe discipline, consciously resist unhealthy practices, give criticism and education, warn or revoke the qualifications of violators according to the seriousness of the case, and report to their units for handling.

Twenty-sixth to obtain excellent site standardization and praise the site, by the Municipal Construction Committee issued a document for the city.

Chapter VII Supplementary Provisions

Twenty-seventh management measures by the Municipal Construction Committee is responsible for the interpretation of.

Article 28 District and county (city) Construction Bureaus and municipal quality safety supervision stations may, in accordance with these measures, formulate measures for the implementation of the selection and management of excellent sites for standardized management of construction safety in construction projects of their own departments (units).

Twenty-ninth the management measures shall be implemented as of July 15, 2020. The original Notice on Printing and Distributing the Measures for the Administration of Standardized Model Construction Sites for Safe Production and Civilized Construction of Construction Projects in Hangzhou (Hangzhou Construction Engineering Development [2005] No.703) and the Notice on Further Strengthening the Administration of Standardized Model Construction Sites for Safe Production and Civilized Construction of Construction Projects in Hangzhou (Hangzhou Construction Engineering Development [2007] No.547) shall be automatically abolished after the implementation of these Measures.

Attachment: 1.(XXXX) Excellent Construction Site with Standardized Management of Construction Safety in Hangzhou Construction Project in 2008

2. Hangzhou construction project construction safety production standardization management excellent site election card to receive a single.

3. Hangzhou Standardized Excellent Site Inspection Self-evaluation Form (used by construction and supervision enterprises)

4. Hangzhou Construction Project Safety Production Standardization Management Excellent Site Declaration Form

5. "Three-stage" inspection and evaluation form (foundation, subject and decoration)

6. Inspection Record Form of Supervisory Body

Notice of Beijing Municipal Bureau of Civil Affairs and Beijing Municipal Bureau of Finance on Issuing Winter Heating Subsidies for Some Special Care recipients

Jing Min You Fa [2018] No.397

District Civil Affairs Bureau and Finance Bureau:

  In order to better reflect the concern of the party and the government for the special care recipients and enhance their sense of acquisition and happiness, it is decided to issue winter heating subsidies to some special care recipients. The relevant matters are hereby notified as follows:

  First, the distribution target

  Enjoy regular pensions and subsidies for rural "coal to clean energy" household self-heating personnel and coal-fired self-heating personnel in winter.

  Special care recipients who enjoy regular pension benefits refer to: survivors of martyrs who enjoy regular pension benefits (including survivors of soldiers who died in the line of duty and survivors of deceased soldiers), veterans of the Red Army who retired in rural areas (including veterans of the Red Army who went west in rural areas and those who lost their lives), disabled soldiers (including disabled people’s police, disabled state functionaries and disabled militia migrant workers), demobilized soldiers, participants in the war, and children of some martyrs (including children of those who were rehabilitated after being killed by mistake before the founding of the People’s Republic of China).

  Second, the subsidy standard

  1 "coal to clean energy" household self-heating rural entitled groups, according to the standard subsidy of 2400 yuan/heating season.

  2 winter coal-fired self-heating entitled groups, according to the standard subsidy of 1350 yuan/heating season.

  3. For the newly approved entitled groups after the start of the heating season, and the remaining statutory heating season has reached or exceeded two months since the date of approval, you can enjoy the relevant subsidies in full; Less than two months, according to the relevant subsidy standards to enjoy 50%. The entitled groups approved in March each year do not enjoy the relevant subsidies in the current season.

  4. At the same time, people (households) who meet the requirements of special care, subsistence allowances, decentralized support for poor, low-income and over-transferred personnel can enjoy the relevant winter heating subsidies (subsidies and assistance), and they can only choose to enjoy one item without repeating it. Non-repeated enjoyment with multiple special care recipients.

  5. Families with special care groups can enjoy the subsidy of "coal to clean energy" for household self-heating, the subsidy of coal-fired self-heating in winter, the subsidy of central heating, and the subsidy of winter heating in work units, so they can only choose one of them, and cannot enjoy it repeatedly.

  6. After the start of the heating season, the heating subsidy will be stopped from the next heating season if the regular pension subsidy is cancelled.

  Third, the issuance procedures

  (a) eligible entitled groups, after being audited by the civil affairs department in the area where the household registration is located, will be given a one-time grant for the statutory heating season (from November 15th of that year to March 15th of the following year) before November 15th of each year.

  (II) Each district shall conduct audit through various channels, such as relevant materials, household surveys, collaborative verification by relevant departments, etc. Anyone who can verify clearly through inter-departmental and other means shall not require the entitled groups to provide relevant materials again, so as to ensure strict and accurate, simplify procedures as much as possible, and maximize the convenience for the entitled groups.

  IV. Funding channels

  "Coal to clean energy" household self-heating subsidies and winter coal-fired self-heating subsidies are financially borne by the areas where their household registration is located. The district finance department shall, jointly with the civil affairs department at the same level, make the annual budget of subsidy funds, and strengthen the audit, supervision and management of funds.

  V. Relevant requirements

  1. Giving winter heating subsidies to some entitled groups is the concern of the party and the government for the entitled groups, which is related to the vital interests of the entitled groups. All districts should attach great importance to it, make careful arrangements, improve the working mechanism according to the actual situation in the region, standardize the operating procedures, and improve various procedures to ensure that good things are done well.

  2. Civil affairs departments should strictly and rigorously do a good job in identity confirmation, condition review, grant payment, etc., to ensure that no leakage is good, timely and accurate. The financial department should do a good job in ensuring funds, strengthen fund supervision, and ensure timely and smooth disbursement of funds and strict use of funds.

  3. The entitled groups should enjoy the treatment according to the policies and regulations, and the civil affairs departments of all districts should criticize and educate them, cancel the treatment in time, and recover the fraudulent funds. If the circumstances are bad and violate laws and regulations, they shall be handed over to the judicial department for handling according to law.

  By the civil affairs department of this Municipality to issue regular pensions to the courageous people and their survivors, winter "coal to clean energy" household self-heating and winter coal-fired self-heating, with reference to the standards, procedures and relevant provisions of this notice to issue winter heating subsidies; For central heating and heating in winter, the winter central heating subsidy shall be issued according to the standards, procedures and relevant regulations of the relevant entitled groups in the Detailed Rules for the Implementation of Central Heating and Heating Subsidies for Special Care, Minimum Living Allowance and Decentralized Support for Poor Persons in Beijing (J.M.S.F.F. [2016] No.50).

  This notice will be implemented from the heating season of 2018-2019. The heating subsidy for the heating season in 2018-2019 will be paid before the end of December 2018.

  Attachment: Registration Form of Winter Heating Subsidy for Beijing Special Care recipients (omitted)

Beijing Municipal Civil Affairs Bureau

beijing finance bureau

October 25, 2018

Many places in the country have successively adjusted the endurance category of the senior high school entrance examination to be exempted or selected.

  On March 10th, the Education Bureau of Hengyang City, Hunan Province issued a notice saying that after comprehensive research, it was decided to adjust the items and time of the physical education examination of Hengyang junior high school academic level examination in 2023: the middle and long-distance race (1000m for men and 800m for women) in the basic test items was adjusted from compulsory examination to exemption examination, and all candidates in this project were given full marks.

  This year, many places in the country have successively adjusted the plans for the senior high school entrance examination for physical education, and some places have adjusted endurance events such as long-distance running and swimming as optional items.

  Among them, on March 8, Hangzhou Education Bureau released the latest adjustment plan for the 2023 senior high school entrance examination physical examination. So far, 11 districts and cities in Zhejiang Province have officially announced the sports programs for this year’s senior high school entrance examination, and the 1000-meter running (boys) /800-meter running (girls) projects have been adjusted to "can run or not".

  The Paper noted that Lishui Education Bureau mentioned in answering questions from the public that candidates infected with novel coronavirus should carefully apply for physical endurance events such as 1000m (male) or 800m (female), and candidates who apply for such events should do a good job in personal health risk assessment.

  Lishui City Education Bureau also reminded that candidates who have been infected with novel coronavirus and other special physique should pay attention to the recovery training of physical skills and gradually increase the difficulty intensity when preparing for the exam. Warm-up exercises should be done before training, physical condition should be paid attention to during training, and rest should be paid attention to in time after training. If necessary, give feedback to the teacher or parents about your physical condition. If you have difficulty breathing, abnormal heart rate or excessive fatigue, you should consult a professional doctor in time.

  In Ji ‘an, Jiangxi Province, the notice issued by the Ji ‘an Municipal Education and Sports Bureau on March 6 stated that in 2023, there will be no compulsory items in the entrance examination for junior and middle school graduates, and the compulsory items (1000m for men/800m for women) will be adjusted to optional items. Candidates choose two items from five selected items for testing.

  The Education and Sports Bureau of Ji ‘an said that all localities should fully understand the background and significance of the adjustment of this year’s physical examination items in the province, that is, from three items of the original examination to two items of the examination, and from the original compulsory examination items to optional examination items, so as to take effective measures to prevent major risks.

  In addition, the "Notice on Doing a Good Job in the Physical Education Examination for Junior and Middle School Graduates in 2023" issued earlier by the Guangdong Provincial Department of Education also adjusted the compulsory items (men’s 1000 meters/women’s 800 meters and swimming) in the unified test project to optional items. The "Notice" pointed out that in view of the current epidemic situation in Guangdong Province and the physical health status of students, in order to effectively ensure the scientific, safe and smooth progress of the physical education examination for junior and middle school graduates in 2023, after in-depth analysis, comprehensive judgment and careful consideration, it was decided to make corresponding adjustments to the physical education entrance examination in Guangdong Province in 2023.

Institute of Neuroscience, Chinese Academy of Sciences: There is the best research soil here.

  At the age of 30, Serina Liu became the head of a research team at the Institute of Neuroscience, China Academy of Sciences.

  It is the dream of young people doing scientific research to set up their own research groups. Serina Liu himself had never thought that this day would come so quickly.

  In 2018, the news that the world’s first somatic cloned monkey was born in the Institute of Neurology, Chinese Academy of Sciences was released, which was one of the most remarkable developments in the global scientific community that year. Behind this major breakthrough is a young team of "Dr. Tu", and Liu is really one of them.

  Serina Liu stood out from the crowd thanks to the innovative mechanism and system of Institute of Neurology, Chinese Academy of Sciences. After years of follow-up interviews with the Institute of Neurology of the Chinese Academy of Sciences, the reporter found that the best scientific research soil is accumulating here. After 20 years of exploring the reform of scientific research system, this young research institute is moving towards the ideal of becoming the world’s top scientific research institution. Aiming at the forefront of the world’s science and technology, a lean and efficient research team is marching forward bravely, striving to lead and promote the upgrading of strategic industries with major breakthroughs in basic scientific research, and make contributions to building an innovative country and building a world science and technology power.

  To grow up "lining", not talent "hat"

  In 2010, Serina Liu was admitted to the Institute of Neurology of Chinese Academy of Sciences from Shandong Normal University to study for a master’s degree, and joined the macaque platform hosted by her tutor Sun Qiang. In 2016, Dr. Serina Liu graduated and published a research paper on genetically modified monkeys with autism in the top international academic magazine Nature. With his academic achievements during his doctoral period, there is no problem in applying for top foreign laboratories. Serina Liu finally decided to stay and continue his postdoctoral research in the institute.

  Go to a good foreign laboratory as a postdoctoral researcher, and after publishing one or two good articles, apply to return to China to be a "thousand young people" — — This is the ideal growth track for most doctors in the field of life sciences after graduation. Moreover, with the "hat" of talents, the support of research funds, preferential policies for settling down and so on can follow. However, if you choose to go abroad, most of you can’t continue the project of "making cloned monkeys", and you can only do "short, flat and fast" projects in other directions.

  The purpose of Serina Liu’s stay is to continue to work on making monkey models of brain diseases. He knows that this is the breakthrough direction of the key layout of the Institute of Neurology of the Chinese Academy of Sciences, and he is eager to join in it. One of the main reasons why most brain diseases can’t be effectively treated is that the current mouse model for developing drugs is far from that of humans, and most of the drugs developed are ineffective or have side effects when tested in humans. The production of disease model monkeys will bring unprecedented bright prospects for the mechanism research, intervention, diagnosis and treatment of brain diseases.

  Muming Poo, an academician of the Chinese Academy of Sciences and director of the Institute of Neurology, also convinced Serina Liu that only by breaking through the somatic cell cloning technology of nonhuman primates can we truly solve a series of shortcomings faced by macaques as experimental animals, establish a competitive advantage in brain science research in China and become an international leader.

  "The domestic scientific research conditions are different, and the state pays more attention to personnel training. It is an inevitable trend to make more and more world-leading achievements in China." Serina Liu said, "In my opinion, no place can provide me with better opportunities and support than the nerve center."

  "For a young scientific research talent who gives up studying abroad and is willing to stay at home to challenge major scientific problems, if the challenge fails, can we correctly evaluate his ability and let him still have a good development prospect?" When Sun Qiang led the team led by Serina Liu to experience numerous failures and achieved the first major breakthrough in the world’s somatic cloning of monkeys, Muming Poo raised a question worth pondering.

  In July 2018, more than eight months after the birth of the cloned monkey, Serina Liu left the station early after only one year of postdoctoral work in the Institute of Neurology, Chinese Academy of Sciences, and was officially hired as a researcher and became a research team leader of the Institute of Neurology.

  In the past year, Serina Liu has obtained the same research start-up funds and operation funds as other researchers in the institute. His laboratory is 130 square meters, equipped with five employees, and recruits one or two students every year. "This is enough for a research group that has just started." Serina Liu said that he intends to complete the optimization and efficiency improvement of somatic cloning monkey technology in three to five years, and at the same time, open some interesting topics step by step, such as the neurobiological mechanism of puberty initiation in primates.

  Serina Liu’s growth trajectory is just one of the cases in which the nervous system does not take the usual path and innovates the system and mechanism.

  Speak by skill, not by title.

  "The research team leader recruited by the Institute of Neurology only looks at whether there is a good job, not whether there is experience in studying abroad." When Serina Liu hesitated to go abroad, Muming Poo’s words reassured him.

  This is not an exception, but a performance-centered talent use and evaluation system that the Institute of Neurology has been insisting on for many years.

  In 1998, the CPC Central Committee and the State Council made a major decision to build a national innovation system, and decided that the Chinese Academy of Sciences would launch a pilot project of knowledge innovation. As one of the important strategic arrangements of the pilot project, Chinese Academy of Sciences established the Institute of Neuroscience in November 1999, with Muming Poo as its director. At that time, the situation could be called "being ordered at a critical moment", and Muming Poo became the first foreign director of the Chinese Academy of Sciences.

  "Only by establishing a brand-new institute of modern scientific research system and using a new system and mechanism can we attract talents." At the beginning of its establishment, Muming Poo made up his mind to innovate the operation and management of scientific research institutes and vigorously reform the traditional scientific research evaluation and incentive system. His goal is to establish a top scientific research institution which is recognized by international peers and whose operation mode can be replicated and popularized in China.

  Since 2003, the Institute of Neurology has taken the lead in introducing an international scientific research evaluation system among national scientific research institutes. Here, heroes don’t ask the source, talents don’t have the distinction of "foreign soil", and researchers should speak by skill, not by title. Even well-known experts should abide by the strict assessment requirements of the institute, and even without a diploma, they can be hired as deputy senior professional and technical posts. All work is to create a good ecological environment for scientific and technological innovation.

  When receiving the olive branch from the nerve, Sun Qiang was still a little-known university lecturer. He graduated from Inner Mongolia University for Nationalities with no overseas study experience. At the age of 36, he had just been awarded the deputy senior title and experienced the failure of developing transgenic monkeys. He once considered whether to give up the research on nonhuman primates. At an academic conference, I learned about Sun Qiang’s practical foundation and technical level for many years. Muming Poo introduced him as a full-time senior engineer and entrusted him with the task of building a research platform for nonhuman primates.

  To work here, Sun Qiang only made one condition to Muming Poo: to bring two veterinarians with only junior college education. Although their education is not high, they are a very important part of the scientific research team and need spirituality and concentration to achieve the ultimate.

  At the beginning of 2018, the world’s first cloned monkey "Zhong Zhong" and "Hua Hua" cultivated by Sun Qiang’s team appeared in Cell magazine. This achievement, independently completed by scientists in China, is known as "a milestone breakthrough in the field of biotechnology in the world". The birth of the cloned monkey also proves that China has reached a stage from gradual and incremental innovation to a major breakthrough.

  Are "Dr. Tu" and "Dr. Tu" not as good as those who have drunk "foreign ink"? Obviously not. Major breakthroughs, such as synthetic insulin, have been made by local scientists in China, most of whom are young scientists. In Muming Poo’s eyes, young people are the most innovative when they are 25 to 35 years old, but many excellent students go abroad as postdoctoral fellows, and devote the time that they can do experiments wholeheartedly to foreign laboratories in order to become "foreign talents" and get the talent "hat" smoothly.

  "It seems that if you don’t go abroad, you can’t find a good job, and you don’t pay enough attention to the local talents you cultivate. This kind of employment orientation must be changed." Muming Poo regrets, "truly successful people don’t necessarily have to go abroad. It is very important to keep excellent doctoral and postdoctoral students in domestic first-class scientific research units and give them opportunities for innovation. There must be various mechanisms to encourage such talents. "

  This is what the nerve has been trying to do. Under the leadership of Muming Poo, the Institute of Neurology has continuously deepened the reform of mechanism and system, and made in-depth and extensive explorations and attempts in the innovation of system and mechanism such as postgraduate training, team research to promote cross-integration, selection and promotion, and evaluation.

  Yan Wang, secretary of the Party Committee of the Institute of Neurology, summed up the basic principles of talent work in the Institute of Neurology — — Provide a relatively stable scientific research environment, so that scientists can focus on research work; Carry out strict international assessment and implement a benign flow mechanism; Guide researchers to resist pressure and temptation, so that young scientists can work in a down-to-earth manner.

  With these three rules, the breakthrough is ahead, and all it takes is time. Of course, it is very important to delve into major issues.

  Stick to "big problems" instead of "short-term" topics.

  "Big problem" is a key word deeply rooted in the culture of the Institute of Neurology.

  It is precisely because of aiming at major scientific problems that the non-human primate research platform is built and perfected. In fact, since 2002, many research institutions in the world have started the research on somatic cell cloning of nonhuman primates. In 2010, Mitalipov, a scientist from Oregon Primate Research Center, led a team to successfully transplant cloned monkey embryos, but unfortunately, the success failed, and the embryos ended in abortion after 81 days of development.

  However, due to the high investment cost and long output cycle of primate research, at first, many researchers who took mice as experimental objects inside and outside the Institute of Neurology were not optimistic about the investment in somatic cloned monkeys. In 2009, Muming Poo made a public opinion, and used the director’s fund layout to build a non-human primate research platform. That year, the Chinese Academy of Sciences tried out the only stable support policy for the whole hospital system, including the director’s fund. Since 2012, the non-human primate research platform project has been supported by Chinese Academy of Sciences. The background is that the Chinese Academy of Sciences, as a national strategic scientific and technological force, launched the strategic pilot science and technology project (Class B) "Study on Brain Function Linkage Map" in this year. This special project is one of the first five Class B pilot projects initiated by the Chinese Academy of Sciences, which is earlier than the start time of related "brain projects" in the United States, Japan and the European Union.

  In 2014, the Chinese Academy of Sciences launched the "First Action" plan, which outlined the reform of the classification of research institutes and comprehensively promoted the reform of institutional mechanisms. In the same year, based on the Institute of Neurology, the Center for Excellence and Innovation in Brain Science of Chinese Academy of Sciences was established, becoming one of the first four centers for Excellence and innovation established by Chinese Academy of Sciences.

  In 2015, during the planning of "China Brain Project", scientists in China put forward a "one body and two wings" architecture, that is, the neural principle of brain cognition as the "main body" and the new means of diagnosis and treatment of brain diseases and the new brain-like intelligent technology as the "two wings". The Chinese Academy of Sciences responded quickly and planned the coordinated development of brain science and brain-like research. The Center for Excellence and Innovation in Brain Science and Intelligent Technology, jointly planned by Institute of Neurology and Institute of Automation, was formally established in this year.

  Major changes have spawned major outputs. Perhaps coincidentally, on November 27th, 2017, the 18th anniversary of the establishment of the Institute of Neurology, the somatic cloned monkey "Zhongzhong" was born. In Muming Poo’s view: "The reason for our success is that we saw that this problem can be solved and stuck to it, while most foreign laboratories gave up. Our success is due to the cohesion of a group of cutting-edge talents. "

  "If you want to make a breakthrough scientific discovery, you must do important problems. I hope that the teachers and students of the Institute of Neurology have the confidence to do the best work, have the confidence and courage to do important problems, and eventually make breakthrough scientific discoveries. " Muming Poo is convinced. The "baton" of evaluation is also guiding everyone to explore innovative major scientific issues in line with the direction of national strategic development, rather than simply doing the topic of "fast, safe and easy to publish articles".

  At the end of November every year, it is the "big gathering" of the Institute of Neurology. After the establishment of the Center for Excellence and Innovation in Brain Science and Intelligent Technology, this tradition continued and became the "big gathering" of the whole center, and the performance evaluation of the year was carried out at the same time as academic exchanges. The evaluation results are the basis for researchers to apply for annual research funds and adjust performance allowances, and directly affect their funding and promotion opportunities.

  The results of performance evaluation are divided into three grades: A, B and C. Members who have been rated as C for two consecutive years will be required to make rectification, and the annual performance allowance will be stopped during the rectification period; Members who have been rated as C for three consecutive years will be asked to withdraw; Members who have been rated as A for two consecutive years will be given priority in promotion assessment.

  Yan Wang remembers that when it was first implemented, the impact was great. Some researchers can’t figure out: why did they get a C in the evaluation because they have sent so many papers with high impact factors? Because the evaluation criteria are different, the "paper-only" evaluation system has been broken since the end of 2015, focusing on the contribution to the team’s key projects, excluding the results unrelated to the team’s projects; There are significant innovative achievements in the key areas of the center layout; The investment in interdisciplinary communication includes multi-unit "squatting" teaching and research, and guiding dual-tutor graduate students.

  What are good results and big results? What kind of achievement is a major breakthrough? "It is a major breakthrough to open up new scientific research fields and achieve milestones in the original scientific research fields. Looking around the world, the world’s top scientific research institutions have such achievements. Every scientific research field has well-known major unsolved problems, and it is the real leader in this field to continuously make major breakthroughs in one field. " Muming Poo said.

  It is necessary to "explore freely" and "tackle key problems by team"

  "It has been 5 years since I returned to China. Let’s see when I can get the first clinical approval." On July 8, Yang Hui, a researcher at the Institute of Neurology, wrote this sentence in a circle of friends, with a smiling expression of high morale.

  In 2014, 29-year-old Yang Hui became the youngest researcher in the Institute of Neurology, and served as the leader of the primate disease model research group and doctoral supervisor. "90% of rare diseases are incurable. Can we do something with gene editing?" Yang Hui said that rare diseases are actually not rare. There are more than 7,000 rare diseases found in the world, with more than 300 million patients, more than cancer patients. The goal of him and his team is to develop more efficient and safer gene editing tools and build a research and development platform for treating rare diseases. "The first gene drug in China will not be too far away".

  In the first half of this year, Yang Hui’s research group had a bumper harvest, and published two papers in Science and Nature. It was the first time in the world to confirm the off-target effect of single-base gene editing, and then further repaired the off-target "loophole" and established a new generation of single-base gene editing tools. The young researcher said frankly: "I’m still very uneasy, and I’m most worried about disappointing the students’ efforts day and night. Teacher Pu is still helping us to change articles over and over again during the Spring Festival holiday. Thank you for your efforts and hope that the results will benefit China patients as soon as possible. "

  The birth of somatic cloned monkeys undoubtedly brought Yang Hui closer to her dream. Starting from 2018, a monthly seminar on cloned monkeys will be held. In addition to the main personnel of the primate platform, many research groups of the Institute of Neurology will participate, expecting to bear more innovative fruits in deep cross-integration. Sun Qiang said that on the basis of successfully constructing the world’s first batch of somaclonal monkeys with dysrhythmia, more efforts are being organized, and the efforts of the Institute, the Center of Excellence and even the whole country are gathered to develop a variety of disease model monkeys and tool monkeys developed by somaclonal monkey technology as soon as possible. "Many research groups in the Institute have cooperated with us."

  In Muming Poo’s view, at present, breakthroughs in most fields require cooperative research, and establishing a concise and efficient research team is the key to a major breakthrough. "The biggest challenge in the biological science community at present is to establish an effective research team." The molecular mechanism and variety design of synthetic bovine insulin with full activity, high yield and high quality rice are not the results of individual combat. To make breakthrough work on major issues requires the team spirit of sincere cooperation, hard work and perseverance of each member, and puts the task and goal of team research above personal gains and losses.

  This is also the first-class scientific research culture that Muming Poo has always advocated, and the first-class scientific research institutions should have. "Looking for the development direction of the frontier of science must be free to explore. However, with the development of science and technology, it is difficult to make a real breakthrough only by individual’s free exploration. Therefore, it is an inevitable trend for young and middle-aged scientists to abandon the limitations of fame and fortune, cooperate with each other and jointly answer important scientific questions. "

  At the beginning of its establishment, the Institute of Neurology insisted on joint team research as the core way to solve major problems, and actively explored the establishment of scientific research systems and mechanisms that take into account collective goals and personal interests, demand orientation and free exploration. Here, most of the personal interests of scientific researchers are respected, most of their personal expertise is found, and valuable and distinctive frontier research fields are basically covered.

  Muming Poo has a profound understanding of the training methods of Chinese and Western scientists, and he hopes to promote the establishment of a new scientific culture in the nerve center and cultivate intellectuals who inherit China’s traditional values. In his view, Chinese researchers should have the spirit of selflessness, and more importantly, they should have the feeling of "worrying about the world first, and enjoying the world later" of China traditional intellectuals, so as to serve the country with scientific and technological achievements.

  "Please don’t buy things you don’t need in the near future. I am very seriously opposed to the idea of spending all the unspent funds before the end of the year. If we can’t use up the money, it means that we don’t need it. We must return it to the Chinese Academy of Sciences or other sources. This is the correct attitude of a scientist with social responsibility. " Muming Poo once sent an email to the research group leader in the institute.

  In his view, it is a basic social conscience that researchers should use research funds cautiously. The level of scientists is expressed by ideas and innovation, not by the latest models of instruments they have. The wind of "grabbing" resources once appeared in academic circles is a waste to society. The practice of the Institute of Neurology also proves this point. The rapid development depends not on the input of resources, but on the ideal of building a world-class scientific research institution and persisting in promoting the reform of the system and mechanism.

  At the beginning of his tenure as director of the Institute of Neurology, Muming Poo once put down his grandiloquence: "I have never been so confident in successfully establishing a world-class research institute on the land of China. This will be a research institute that will be recorded in the history of science in China. As the first director of the Institute of Neurology, I am determined to do my best to turn the Institute of Neurology into a fertile soil where the seeds of scientific invention will sprout, take root and blossom. "

  This year, 71-year-old Muming Poo will soon witness the 20th year of this research institute, which has devoted countless efforts to it, and complete another major turn. In the near future, it will continue to complete its mission and responsibility under the name of "Center for Excellence in Innovation of Brain Science and Intelligent Technology of Chinese Academy of Sciences".

  Innovation, innovation, and innovation.

  Fusion, fusion, re-fusion.

  This is the result of the times and the general trend. At present, the research of brain science and intelligent technology is facing unprecedented development opportunities. After 20 years of intensive cultivation, a research team led by outstanding scientists and with outstanding young scientists as the main body has become increasingly mature and has become a main force in the research of brain science and intelligent technology in China. After 20 years of reform and innovation, the rivers crossed, the bridges crossed and the roads traversed have been integrated into the great process of China’s scientific and technological innovation to overcome difficulties and become a cornerstone to consolidate the innovation-driven development strategy. (Reporter Yan Weiqi)